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Displaying results 1 - 10 of 25 in total
  1. Target

    MIO-dependent tyrosine 2,3-aminomutase

    go.drugbank.com/bio_entities/BE0003755
    TargetStreptomyces globisporus

    Catalyzes the MIO-dependent deamination of L-tyrosine generating the corresponding alpha,beta-unsaturated acid, (S)-beta-tyrosine.

    Polypeptides: MIO-dependent tyrosine 2,3-aminomutase
  2. Target

    Proprotein convertase subtilisin/kexin type 9

    go.drugbank.com/bio_entities/BE0008643
    TargetHumans

    Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LR...

    Polypeptides: Proprotein convertase subtilisin/kexin type 9Synonyms: Subtilisin/kexin-like protease PC9
  3. Target

    Aromatic-amino-acid aminotransferase

    go.drugbank.com/bio_entities/BE0001389
    TargetParacoccus denitrificans

    Shows activities toward both dicarboxylic and aromatic substrates.

    Synonyms: ARAT
  4. Target

    Protein Rev

    go.drugbank.com/bio_entities/BE0010935
    TargetHuman immunodeficiency virus type 1 group M subtype B (isolate HXB2)

    Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not pres...

    Synonyms: ART/TRS
  5. Target

    Diacylglycerol O-acyltransferase 2

    go.drugbank.com/bio_entities/BE0008719
    EnzymeTargetHumans

    Also functions as an acyl-CoA retinol acyltransferase (ARAT) (By similarity).

    Synonyms: ARAT
  6. Target

    Metalloproteinase inhibitor 3

    go.drugbank.com/bio_entities/BE0003371
    TargetHumans

    Mediates a variety of processes including matrix regulation and turnover, inflammation, and angiogenesis, through reversible inhibition of zinc protease superfamily enzymes, primarily matrix metalloproteinases (MMPs). Regulates extracell...

    Synonyms: Protein MIG-5
  7. Target

    2-methylisocitrate lyase

    go.drugbank.com/bio_entities/BE0001259
    TargetEscherichia coli (strain K12)

    Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and su...

    Synonyms: 2-MIC
  8. Target

    Creatine kinase S-type, mitochondrial

    go.drugbank.com/bio_entities/BE0000410
    TargetHumans

    Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such a...

    Synonyms: Mib-CK
  9. Target

    Diacylglycerol O-acyltransferase 1

    go.drugbank.com/bio_entities/BE0012021
    TargetHumans

    Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders (PubMed:16214399

    Synonyms: ARAT
  10. Target

    Piezo-type mechanosensitive ion channel component 1

    go.drugbank.com/bio_entities/BE0017696
    TargetHumans

    Pore-forming subunit of the mechanosensitive non-specific cation Piezo channel required for rapidly adapting mechanically activated (MA) currents and has a key role in sensing touch and tactile pain (PubMed:23479567, PubMed:23695678, Pub...

    Synonyms: Mib