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Lymphocyte antigen 75
go.drugbank.com/bio_entities/BE0010744TargetHumansActs as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes
Polypeptides: Lymphocyte antigen 75Synonyms: Ly-75NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
go.drugbank.com/bio_entities/BE0000493TargetHumansCore subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30879903, PubMed:3155...
Polypeptides: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrialHeat shock protein 75 kDa, mitochondrial
go.drugbank.com/bio_entities/BE0014134TargetHumansChaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the bala...
Polypeptides: Heat shock protein 75 kDa, mitochondrialSynonyms: HSP 75Type II inositol 1,4,5-trisphosphate 5-phosphatase
go.drugbank.com/bio_entities/BE0004437TargetHumansRegulates phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) cellular levels by cleaving the phosphate at the 5-position producing PtdIns(4)P. Also hydrolyzes the 5-position phosphate from inositol 1,4,5-trisphosphate (Ins(1,4,5)P3), ...
Synonyms: 75 kDa inositol polyphosphate-5-phosphataseTransitional endoplasmic reticulum ATPase
go.drugbank.com/bio_entities/BE0004572TargetHumansNecessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to...
Synonyms: 15S Mg(2+)-ATPase p97 subunitNuclear receptor coactivator 2
go.drugbank.com/bio_entities/BE0003740TargetHumansTranscriptional coactivator for steroid receptors and nuclear receptors (PubMed:23508108, PubMed:8670870, PubMed:9430642, PubMed:22504882, PubMed:26553876). Coactivator of the steroid binding domain (AF-2) but not of the modulating N-ter...
Synonyms: Class E basic helix-loop-helix protein 755,6-dihydroxyindole-2-carboxylic acid oxidase
go.drugbank.com/bio_entities/BE0010503TargetHumansPlays a role in melanin biosynthesis (PubMed:16704458, PubMed:22556244, PubMed:23504663). Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ...
Synonyms: Glycoprotein 75Interleukin-2 receptor subunit beta
go.drugbank.com/bio_entities/BE0000651TargetHumansReceptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (...
Synonyms: p70-75Interleukin-2 receptor
go.drugbank.com/bio_entities/BE0027978TargetHumansCommon subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770)
Synonyms: p70-75