Search

Displaying results 1 - 10 of 736 in total
  1. Target

    Leucine-rich repeat-containing G protein-coupled receptor 5

    go.drugbank.com/bio_entities/BE0010835
    TargetHumans

    Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle.

    Polypeptides: Leucine-rich repeat-containing G protein-coupled receptor 5Synonyms: G protein-coupled receptor 49, G protein-coupled receptor 67
  2. Target

    Insulin receptor

    go.drugbank.com/bio_entities/BE0000033
    TargetHumans

    When present in a hybrid receptor with IGF1R, binds IGF1. … Receptor tyrosine kinase which mediates the pleiotropic actions of insulin.

    Polypeptides: Insulin receptor
  3. Target

    Estrogen receptor

    go.drugbank.com/bio_entities/BE0000123
    TargetHumans

    Nuclear hormone receptor. … Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner.

    Polypeptides: Estrogen receptorSynonyms: Estradiol receptor, Nuclear receptor subfamily 3 group A member 1
  4. Target

    Secretin receptor

    go.drugbank.com/bio_entities/BE0000318
    TargetHumans

    Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and activates cAMP-dependent pathway (PubMed:32811827, PubMed:33008599). … G protein-coupled receptor activated by secretin (SCT), which is involved in different processes such as regulation of the pH of the duodenal content, food intake and water homeostasis (PubMed:25332973

    Polypeptides: Secretin receptorFunction: G protein-coupled peptide receptor activity
  5. Target

    Prolactin receptor

    go.drugbank.com/bio_entities/BE0000345
    TargetHumans

    This is a receptor for the anterior pituitary hormone prolactin (PRL).

    Polypeptides: Prolactin receptor
  6. Target

    Thyrotropin receptor

    go.drugbank.com/bio_entities/BE0000490
    TargetHumans

    Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). … Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258).

    Polypeptides: Thyrotropin receptorSynonyms: Thyroid-stimulating hormone receptor
  7. Target

    Progesterone receptor

    go.drugbank.com/bio_entities/BE0000557
    TargetHumans

    Depending on the isoform, progesterone receptor functions as a transcriptional activator or repressor

    Polypeptides: Progesterone receptorSynonyms: Nuclear receptor subfamily 3 group C member 3
  8. Target

    Glucocorticoid receptor

    go.drugbank.com/bio_entities/BE0000794
    TargetHumans

    Receptor for glucocorticoids (GC) (PubMed:27120390, PubMed:37478846).

    Polypeptides: Glucocorticoid receptorSynonyms: Nuclear receptor subfamily 3 group C member 1
  9. Target

    Ferripyoverdine receptor

    go.drugbank.com/bio_entities/BE0001305
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    Receptor for the siderophore ferripyoverdine.

    Polypeptides: Ferripyoverdine receptorSynonyms: Ferripyoverdine receptor precursor
  10. Target

    Leptin receptor

    go.drugbank.com/bio_entities/BE0003376
    TargetHumans

    Receptor for hormone LEP/leptin (Probable) (PubMed:22405007).

    Polypeptides: Leptin receptorSynonyms: OB receptor