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Displaying results 1 - 10 of 737 in total
  1. Target

    Pregnancy zone protein

    go.drugbank.com/bio_entities/BE0009089
    TargetHumans

    Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves...

    Polypeptides: Pregnancy zone protein
  2. Target

    Leucine-rich repeat-containing G protein-coupled receptor 5

    go.drugbank.com/bio_entities/BE0010835
    TargetHumans

    Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle.

    Polypeptides: Leucine-rich repeat-containing G protein-coupled receptor 5Synonyms: G protein-coupled receptor 49, G protein-coupled receptor 67
  3. Target

    Ferripyoverdine receptor

    go.drugbank.com/bio_entities/BE0001305
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    Receptor for the siderophore ferripyoverdine.

    Polypeptides: Ferripyoverdine receptorSynonyms: Ferripyoverdine receptor precursor
  4. Target

    Transferrin receptor

    go.drugbank.com/bio_entities/BE0004850
    TransporterTargetHumans

    Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (PubMed:26214738, PubMed:41772062). … The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor.

    Polypeptides: Transferrin receptor protein 1, Transferrin receptor protein 2Synonyms: Transferrin receptor 1
  5. Target

    Dopamine receptor

    go.drugbank.com/bio_entities/BE0009376
    TargetHumans

    Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:39094559) … Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:40683247)

    Polypeptides: Dopamine receptor D1, Dopamine receptor D2Synonyms: Dopamine D1 receptor, Dopamine D2 receptor
  6. Target

    Motilin receptor

    go.drugbank.com/bio_entities/BE0003521
    TargetHumans

    Receptor for motilin

    Polypeptides: Motilin receptorSynonyms: G protein-coupled receptor 38
  7. Target

    Leptin receptor

    go.drugbank.com/bio_entities/BE0003376
    TargetHumans

    Receptor for hormone LEP/leptin (Probable) (PubMed:22405007).

    Polypeptides: Leptin receptorSynonyms: OB receptor
  8. Target

    Secretin receptor

    go.drugbank.com/bio_entities/BE0000318
    TargetHumans

    G protein-coupled receptor activated by secretin (SCT), which is involved in different processes such as regulation of the pH of the duodenal content, food intake and water homeostasis (PubMed:25332973 … Mechanistically, secretin released by the gut after a meal binds to secretin receptor (SCTR) in brown adipocytes, activating brown fat thermogenesis by stimulating lipolysis, which is sensed in the brain

    Polypeptides: Secretin receptorFunction: G protein-coupled peptide receptor activity
  9. Target

    Progesterone receptor

    go.drugbank.com/bio_entities/BE0000557
    TargetHumans

    Depending on the isoform, progesterone receptor functions as a transcriptional activator or repressor

    Polypeptides: Progesterone receptorSynonyms: Nuclear receptor subfamily 3 group C member 3
  10. Target

    Prolactin receptor

    go.drugbank.com/bio_entities/BE0000345
    TargetHumans

    This is a receptor for the anterior pituitary hormone prolactin (PRL).

    Polypeptides: Prolactin receptor