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Displaying results 1 - 10 of 15 in total
  1. Target

    Apolipoprotein B-100

    go.drugbank.com/bio_entities/BE0009908
    TargetHumans

    Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). … Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor

    Polypeptides: Apolipoprotein B-100Synonyms: Apo B-100
  2. Target

    mRNA of ApoB-100

    go.drugbank.com/bio_entities/BE0004845
    TargetHumans

  3. Target

    Transitional endoplasmic reticulum ATPase

    go.drugbank.com/bio_entities/BE0004572
    TargetHumans

    Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to...

    Synonyms: 15S Mg(2+)-ATPase p97 subunit
  4. Target

    Endothelin receptor type B

    go.drugbank.com/bio_entities/BE0000043
    TargetHumans

    Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system

    Synonyms: ET-B, ET-BR
  5. Target

    Interphotoreceptor matrix proteoglycan 2

    go.drugbank.com/bio_entities/BE0004942
    TargetHumans

    Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin

    Synonyms: IPM 200, Interphotoreceptor matrix proteoglycan of 200 kDa
  6. Target

    Protein S100-A1

    go.drugbank.com/bio_entities/BE0001090
    TargetHumans

    Small calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation (PubMed:12804600). In response to an increase in intracellular Ca(2+) l...

    Synonyms: S-100 protein alpha chain, S-100 protein subunit alpha
  7. Target

    Protein S100-B

    go.drugbank.com/bio_entities/BE0001177
    TargetHumans

    Small zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain (PubMed:20950652, PubMed:6487634). Weakly binds calcium but binds zinc very tightly-di...

    Synonyms: S-100 protein beta chain, S-100 protein subunit beta
  8. Target

    Vascular cell adhesion protein 1

    go.drugbank.com/bio_entities/BE0001114
    TargetHumans

    Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation (PubMed:31310649). Acts as a major regulator of leukocyte adhesion to the endothe...

    Synonyms: INCAM-100
  9. Target

    Endothelin-1 receptor

    go.drugbank.com/bio_entities/BE0000521
    TargetHumans

    The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3

    Synonyms: ET-A
  10. Target

    Solute carrier family 22 member 4

    go.drugbank.com/bio_entities/BE0000757
    TargetTransporterHumans

    Transporter that mediates the transport of endogenous and microbial zwitterions and organic cations (PubMed:10215651, PubMed:15107849, PubMed:15795384, PubMed:16729965, PubMed:20601551, PubMed:22206629, PubMed:22569296, PubMed:29530864)....

    Synonyms: ET transporter