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Displaying results 1 - 10 of 25 in total
  1. Target

    Glycogen phosphorylase, liver form

    go.drugbank.com/bio_entities/BE0000007
    TargetHumans

    Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis

    Polypeptides: Glycogen phosphorylase, liver form
  2. Target

    Glycogen phosphorylase, muscle form

    go.drugbank.com/bio_entities/BE0000916
    TargetHumans

    Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis

    Polypeptides: Glycogen phosphorylase, muscle form
  3. Target

    Glycogen phosphorylase, brain form

    go.drugbank.com/bio_entities/BE0002150
    TargetHumans

    Glycogen phosphorylase that regulates glycogen mobilization (PubMed:27402852). Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228). Enzymes from different sources differ in their regulatory mechani...

    Polypeptides: Glycogen phosphorylase, brain form
  4. Target

    Neurotrophic factor BDNF precursor form

    go.drugbank.com/bio_entities/BE0003394
    TargetHumans

    Important signaling molecule that activates signaling cascades downstream of NTRK2 (PubMed:11152678). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous sy...

    Polypeptides: Neurotrophic factor BDNF precursor form
  5. Target

    Vascular endothelial growth factor A, long form

    go.drugbank.com/bio_entities/BE0000163
    TargetHumans

    Participates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A (PubMed:35455969). Involved in protecting cells from hypoxia-mediated cell death (By similarity)

    Polypeptides: Vascular endothelial growth factor A, long form
  6. Target

    Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial

    go.drugbank.com/bio_entities/BE0000609
    TargetHumans

    Together with PDHB forms the heterotetrameric E1 subunit of the pyruvate dehydrogenase (PDH) complex in testis (PubMed:14638692). The PDH complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links cyt...

    Polypeptides: Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
  7. Target

    Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

    go.drugbank.com/bio_entities/BE0000571
    TargetEnzymeHumans

    Together with PDHB forms the heterotetrameric E1 subunit of the pyruvate dehydrogenase (PDH) complex (PubMed:17474719, PubMed:19081061). The PDH complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby li...

    Polypeptides: Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
  8. Target

    Calbindin

    go.drugbank.com/bio_entities/BE0008690
    CarrierHumans

    Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase

    Synonyms: Vitamin D-dependent calcium-binding protein, avian-type
  9. Target

    Hexokinase-2

    go.drugbank.com/bio_entities/BE0009792
    TargetHumans

    Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:23185017, PubMed:26985301, PubMed:29298880). Mediates the initial s...

    Synonyms: Muscle form hexokinase
  10. Target

    Hexokinase-1

    go.drugbank.com/bio_entities/BE0001108
    TargetEnzymeHumans

    Catalyzes the phosphorylation of various hexoses, such as D-glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6...

    Synonyms: Brain form hexokinase