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Displaying all 10 results
  1. Drug

    Bendamustine

    go.drugbank.com/drugs/DB06769
    ApprovedInvestigational

    Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. … Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death.

    Synonyms: Bendamustine, BendamustinaSalts: Bendamustine hydrochloride, Bendamustine hydrochloride monohydrate
  2. Pathway

    Bendamustine Action Pathway

    smpdb.ca/view/SMP0126606
    Drug action

    Bendamustine is a nitrogen mustard used as an antineoplastic in chemotherapy. … Bendamustine is administered as an intravenous or parenteral injection.

    Drugs: Adenine · Bendamustine
  3. Drug

    Tinostamustine

    go.drugbank.com/drugs/DB15147
    Investigational

    Tinostamustine is under investigation in clinical trial NCT03452930 (Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma).

    Salts: Tinostamustine hydrochloride
  4. Indication

    Refractory Indolent B-Cell Non-Hodgkin Lymphoma

    go.drugbank.com/conditions/DBCOND0165948
    Drugs: Bendamustine
  5. Indication

    Recurrent multiple myeloma

    go.drugbank.com/conditions/DBCOND0025643
    Drugs: Bendamustine
  6. Indication

    Follicular Non-Hodgkin's Lymphoma Refractory

    go.drugbank.com/conditions/DBCOND0110844
    Drugs: Bendamustine · Ibritumomab tiuxetan
  7. Indication

    Refractory Hodgkin Lymphoma

    go.drugbank.com/conditions/DBCOND0029144
    Drugs: Bendamustine · Carboplatin · Carmustine · Lomustine
  8. Indication

    Waldenstrom's Macroglobulinemia

    go.drugbank.com/conditions/DBCOND0031369
    Drugs: Bendamustine · Chlorambucil · Doxorubicin · Ibrutinib · Thalidomide · Zanubrutinib
  9. Indication

    Mantle Cell Lymphoma (MCL)

    go.drugbank.com/conditions/DBCOND0071979
    Drugs: Acalabrutinib · Bendamustine · Bortezomib · Chlorambucil · Lenalidomide · Rituximab +1 more
  10. Indication

    Refractory Mantle Cell Lymphoma

    go.drugbank.com/conditions/DBCOND0041116
    Drugs: Bendamustine · Brexucabtagene autoleucel · Ibrutinib · Lisocabtagene maraleucel · Pirtobrutinib · Sonrotoclax