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Displaying targets 3176 - 3200 of 6103 in total
TargetOrganismDescription# of Drugs
Lanosterol synthaseHumansKey enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol,...  more2Details
Lantibiotic cinnamycinStreptoverticillium griseoverticillatumCan act as inhibitor of the enzyme phospholipase A2, and of the angiotensin-converting enzyme. Shows inhibitory activ...  more1Details
Lantibiotic mersacidinBacillus sp. (strain HIL-Y85/54728)Kills a number of Gram-positive bacteria. Acts at the level of cell wall biosynthesis by interfering with bacterial p...  more3Details
Lantibiotic nisin-ZLactococcus lactis subsp. lactisLanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity o...  more1Details
Large neutral amino acids transporter small subunit 1HumansForms a heterodimer with SLC3A2 that functions as a sodium-independent transporter for large neutral amino acids. Fun...  more23Details
Large neutral amino acids transporter small subunit 2HumansAssociates with SLC3A2 to form a functional heterodimeric complex that translocates small and large neutral amino aci...  more6Details
Large ribosomal subunit protein bL27Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Found on the solvent side of the large subunit.1Details
Large ribosomal subunit protein bL32Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)Forms a cluster with L17 and L22, and with L22, a pair of 'tweezers' that hold together all the domains of the 23S rR...  more1Details
Large ribosomal subunit protein eL14HumansComponent of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synth...  more1Details
Large ribosomal subunit protein eL15HumansComponent of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synth...  more3Details
Large ribosomal subunit protein eL18HumansComponent of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synth...  more1Details
Large ribosomal subunit protein eL19HumansComponent of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synth...  more3Details
Large ribosomal subunit protein eL37HumansComponent of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synth...  more5Details
Large ribosomal subunit protein uL1Staphylococcus aureus (strain NCTC 8325)Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.2Details
Large ribosomal subunit protein uL10Shigella flexneriProtein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by bindi...  more3Details
Large ribosomal subunit protein uL11Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.2Details
Large ribosomal subunit protein uL13HumansAssociated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Comp...  more3Details
Large ribosomal subunit protein uL14HumansComponent of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synth...  more3Details
Large ribosomal subunit protein uL16Escherichia coli (strain K12)This protein binds directly to 23S ribosomal RNA and is located at the A site of the peptidyltransferase center. It c...  more1Details
Large ribosomal subunit protein uL16HumansComponent of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a...  more1Details
Large ribosomal subunit protein uL2HumansComponent of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synth...  more3Details
Large ribosomal subunit protein uL2Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S riboso...  more1Details
Large ribosomal subunit protein uL22Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and...  more1Details
Large ribosomal subunit protein uL22Escherichia coli O157:H7This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and...  more1Details
Large ribosomal subunit protein uL22Plasmodium falciparum (isolate 3D7)Not Available1Details
Displaying targets 3176 - 3200 of 6103 in total