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Displaying targets 3101 - 3125 of 6103 in total
TargetOrganismDescription# of Drugs
Keratin, type II cytoskeletal 7HumansBlocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulatio...  more2Details
Keratin, type II cytoskeletal 8HumansStructural component of intermediate filaments in simple epithelial cells. Together with its obligate type I partner ...  more2Details
Keratin-associated protein 5-2HumansIn the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hai...  more2Details
Keratin-associated protein 5-3HumansIn the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hai...  more1Details
Ketimine reductase mu-crystallinHumansCatalyzes the NAD(P)H-dependent reduction of imine double bonds of a number of cyclic ketimine substrates, including ...  more1Details
KetohexokinaseHumansCatalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate1Details
Ketosamine-3-kinaseHumansKetosamine-3-kinase involved in protein deglycation by mediating phosphorylation of ribuloselysine and psicoselysine ...  more1Details
Killer cell immunoglobulin-like receptor 2DL1HumansReceptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thu...  more2Details
Killer cell immunoglobulin-like receptor 2DL2HumansReceptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus prev...  more2Details
Killer cell immunoglobulin-like receptor 2DL3HumansReceptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK c...  more2Details
Killer cell immunoglobulin-like receptor 3DL2HumansReceptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open ...  more1Details
Kinesin-1 heavy chainHumansMicrotubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of n...  more1Details
Kinesin-like protein KIF11HumansMotor protein required for establishing a bipolar spindle and thus contributing to chromosome congression during mito...  more16Details
Kinesin-like protein KIF1AHumansKinesin motor with a plus-end-directed microtubule motor activity. It is required for anterograde axonal transport of...  more2Details
Kinesin-like protein KIF2CHumansIn complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulate...  more1Details
Kininogen-1HumansKininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping t...  more9Details
KiSS-1 receptorHumansReceptor for kisspeptins (kisspeptin-10, kisspeptin-13, kisspeptin-14 and metastin/kisspeptin-54). The hypothalamic K...  more3Details
Knob-associated histidine-rich proteinPlasmodium falciparumKAHRP might mimick human histidine-rich glycoproteins to anchor host thrombospondin or a parasite analog in a binding...  more1Details
Krueppel-like factor 4HumansTranscription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the p...  more1Details
KynureninaseHumansCatalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-...  more4Details
KynureninasePseudomonas fluorescensCatalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-...  more1Details
Kynurenine 3-monooxygenaseHumansCatalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis...  more1Details
Kynurenine--oxoglutarate transaminase 1HumansCatalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an...  more8Details
Kynurenine--oxoglutarate transaminase 3HumansCatalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an...  more1Details
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrialHumansTransaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine...  more3Details
Displaying targets 3101 - 3125 of 6103 in total