Displaying drugs 3201 - 3225 of 11493 in total
Nitrazepam
A benzodiazepine derivative used as an anticonvulsant and hypnotic.
Approved
Matched Description: … A benzodiazepine derivative used as an anticonvulsant and hypnotic. …
Ferric sulfate
Ferric sulfate has the molecular formula of Fe2SO4, and it is a dark brown or yellow chemical agent with acidic properties. It is produced by the reaction of sulfuric acid and an oxidizing agent. It is used in different fields such as dermatology, dentistry and it is thought to present...
Approved
Matched Description: … Ferric sulfate has the molecular formula of Fe2SO4, and it is a dark brown or yellow chemical agent with ... [A32355, A32356] By the FDA, ferric sulfate is a direct food substance affirmed in the GRAS category …
Davesomeran
Davesomeran is a mRNA vaccine used in conjunction with elasomeran as part of the Moderna Bivalent COVID-19 vaccine. Similar to the previous Moderna COVID-19 vaccine, Moderna Bivalent vaccine encodes the full-length pre-fusion stabilized spike (S) protein to elicit an immune response.[L43882,L28026] However, with the addition of davesomeran, Moderna Bivalent vaccine...
Approved
Investigational
Matched Description: … Davesomeran is a mRNA vaccine used in conjunction with [elasomeran] as part of the Moderna Bivalent COVID ... Bivalent vaccine elicit a higher seroresponse both against the original SARS-CoV-2 strain and the BA ... [L43882] A phase 2 and 3 open-label study in participants 18 years or older who had previously received …
Peginterferon alfa-2b
Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Use of Peginterferon alfa-2b is associated with a wide range of severe adverse effects including the …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Fosamprenavir
Fosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.
Approved
Matched Description: … Fosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease …
Benzydamine
Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system.
Although the indazole analogue benzydamine is a...
Approved
Matched Description: … Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting ... Although the indazole analogue benzydamine is a non-steroidal anti-inflammatory drug (NSAID), it has ... Moreover, unlike aspirin-like NSAIDs which are acids or metabolised to acids, benzydamine is in fact a …
Ferrous succinate
Approved
Oxazepam
Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. Oxazepam, like related 3-hydroxybenzodiazepine lorazepam, is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) - this feature is advantageous as compared to other benzodiazepines, and is likely owing in...
Approved
Eptifibatide
Synthetic cyclic hexapeptide that binds to platelet receptor glycoprotein and inhibits platelet aggregation. Derived from venom of the Southeastern pygmy rattlesnake (Sistrurus miliarus barbouri), eptifibatide is a cyclic heptapeptide that belongs to the class of arginin-glycin-aspartat-mimetics.
Approved
Investigational
Matched Description: … Derived from venom of the Southeastern pygmy rattlesnake (Sistrurus miliarus barbouri), eptifibatide is a …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Description: … Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme ... Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy …
Olipudase alfa
Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Description: … [L42740] ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a …
Oxidronic acid
Approved
Zinc ascorbate
Approved
Nutraceutical
Tryptophan
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Description: … It is a precursor of indole alkaloids in plants. ... It can be a precursor to niacin, albeit inefficiently, in mammals. ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). …
Protein S human
Protein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties . It serves as a negative feedback mechanism in the coagulation cascade.
Approved
Matched Description: … It serves as a negative feedback mechanism in the coagulation cascade. ... Protein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties [A19561 …
Dienogest
Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not...
Approved
Matched Description: … It is a derivative of 19-nortestosterone and has antiandrogenic properties. ... It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination …
Magnesium gluconate
Magnesium gluconate is a magnesium salt of gluconate. It demonstrates the highest oral bioavailability of magnesium salts and is used as a mineral supplement. Magnesium is ubiquitous in the human body, and is naturally present in many foods, added to other food products, available as a dietary supplement and used...
Approved
Investigational
Matched Description: … Magnesium gluconate is a magnesium salt of gluconate. ... It demonstrates the highest oral bioavailability of magnesium salts [L2608] and is used as a mineral ... the human body, and is naturally present in many foods, added to other food products, available as a …
Tralokinumab
Atopic dermatitis (AD) is an inflammatory skin disorder that causes skin inflammation, skin barrier dysfunction, and chronic pruritus. It is estimated to affect up to 20% of adults and children worldwide, and is frequently associated with other atopic conditions such as asthma or allergic rhinitis. While AD is a heterogenous...
Approved
Investigational
Matched Description: … While AD is a heterogenous condition with a variety of apparent genetic and environmental causes,[A242422 ... [A242427]
Tralokinumab is a fully human IgG4 monoclonal antibody targeted against IL-13. …
Hyoscyamine
Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Matched Description: … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. ... [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic …
Nimesulide
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has...
Approved
Investigational
Withdrawn
Matched Description: … Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic …
Gepirone
Gepirone, an azapirone, is a pharmacologic analog of buspirone that acts selectively on the pre- and post-synaptic 5HT1A receptors. Although earlier clinical trials showed promising results for gepirone, its formulation as an immediate-release tablet necessitates frequent administration due to the short half-lives. It was not until an extended-release formulation of...
Approved
Investigational
Matched Description: … potential candidate for a new antidepressant. ... Gepirone, an azapirone, is a pharmacologic analog of [buspirone] that acts selectively on the pre- and ... It was not until an extended-release formulation of gepirone was made available that gepirone became a …
Rolitetracycline
A pyrrolidinylmethyl tetracycline.
Approved
Matched Description: … A pyrrolidinylmethyl tetracycline. …
Plantago seed
Platango seeds refer to the seeds collected from various species of plantago trees. It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements. Its potential benefit in maintaining remission in ulcerative colitis has been studied .
Regardless, this agent is most predominantly used as...
Approved
Investigational
Matched Description: … Regardless, this agent is most predominantly used as a gentle laxative agent in many parts of the world …
Guanethidine
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. [PubChem]
Approved
Letermovir
Letermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors. Letermovir has recieved both priority and orphan drug status...
Approved
Investigational
Matched Description: … [L1021] It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors …
Displaying drugs 3201 - 3225 of 11493 in total