Displaying drugs 3751 - 3775 of 11778 in total
Dalbavancin
Dalbavancin is a second-generation lipoglycopeptide antibiotic that was designed to improve on the natural glycopeptides currently available, such as vancomycin and teicoplanin [A4072, A4073]. Modifications from these older glycoprotein classes facilitated a similar mechanism of action for dalbavancin but with increased activity and once-weekly dosing [FDA Label, F2356, A4072, A4073]....
Approved
Investigational
Matched Description: … Dalbavancin is a second-generation lipoglycopeptide antibiotic that was designed to improve on the natural ... Modifications from these older glycoprotein classes facilitated a similar mechanism of action for dalbavancin …
Calcium threonate
Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement . It is found in dietary supplements as a source of L-threonate used in the treatment of calcium deficiency and prevention of osteoporosis. The most common...
Approved
Matched Description: … Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of ... osteoporosis and as a calcium supplement [A27266]. ... It is found in dietary supplements as a source of L-threonate used in the treatment of calcium deficiency …
Eleuthero
Eleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Eleuthero is a plant/plant extract used in some OTC (over-the-counter) products. …
Human papillomavirus type 16 L1 capsid protein antigen
Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Description: … Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human …
Human papillomavirus type 33 L1 capsid protein antigen
Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 33. The vaccine is prepared from the purified...
Approved
Matched Description: … Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular …
Isosorbide mononitrate
Isosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload.[L11698, L11743] Isosorbide mononitrate is an active metabolite of isosorbide dinitrate. Like other organic nitrates, isosorbide mononitrate...
Approved
Matched Description: … [L11743] Isosorbide mononitrate has a longer duration of action than [nitroglycerin] due to its slow ... Like other organic nitrates, isosorbide mononitrate acts as a prodrug for its active metabolite, [nitric …
Cefpodoxime
Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria. Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.
Approved
Vet approved
Matched Description: … Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug …
Dezocine
Dezocine is a partial opiate drug and is used for pain management. Dezocine is a very effective alternative to fentanyl when administered during outpatient laparoscopy, although is associated with an increased incidence of postoperative nausea.
Approved
Investigational
Matched Description: … Dezocine is a partial opiate drug and is used for pain management. ... Dezocine is a very effective alternative to fentanyl when administered during outpatient laparoscopy, …
Ozenoxacin
To date, ozenoxacin has been used in trials studying the treatment of impetigo.
As of December 11, 2017 the FDA approved Ferrer Internacional S.A.'s Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by Staphylococccus aureus or Streptococcus pyogenes in adult and pediatric patients...
Approved
Investigational
Matched Description: … s Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by ... Despite being a common and highly contagious bacerial skin infection that affects millions of children ... and adults in the United States each year, ozenoxacin cream is a novel, non-fluorinated quinolone that …
Sodium metavanadate
Approved
Experimental
Typhoid Vi polysaccharide vaccine
Typhoid Vi polysaccharide vaccine is a vaccine that is administered intramuscularly. It is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for use in persons two years of age or older. The vaccine contains the purified cell surface Vi polysaccharide extracted from...
Approved
Matched Description: … Typhoid Vi polysaccharide vaccine is a vaccine that is administered intramuscularly. …
Ravulizumab
Ravulizumab is a potent and selective complement 5 (C5) inhibitor. It is a humanized monoclonal IgG2/4 kappa antibody produced in Chinese hamster ovary (CHO) cells. Ravulizumab was engineered from eculizumab, another complement inhibitor, to increase the duration of action and reduce the frequency of drug administration. It works by blocking...
Approved
Investigational
Matched Description: … Ravulizumab is a potent and selective complement 5 (C5) inhibitor. ... It is a humanized monoclonal IgG2/4 kappa antibody produced in Chinese hamster ovary (CHO) cells. …
Mecasermin rinfabate
Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Description: … In 2007 Insmed withdrew their application for a marketing authorization with The European Medicines Agency …
Methylene blue
Methylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered...
Approved
Investigational
Isavuconazole
Isavuconazole is an triazole antifungal with broad spectrum of activity and good safety profile . It is approved by the FDA and EMA for the treatment of invasive aspergillosis and mucormycosis. It works by inhibiting fungal cell membrane synthesis. Invasive fungal infections pose significant clinical challenges for patients, especially those...
Approved
Investigational
Matched Description: … proposed that the intravenous and oral dosing can be used interchangeably [L1482], without the need for a ... antifungals that requires cyclodextrin for facilitating drug solubility; this is because cyclodextrin has a …
Cyclandelate
A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia. Cyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries.
Approved
Matched Description: … A direct-acting smooth muscle relaxant used to dilate blood vessels. …
Baccharis sarothroides whole
Baccharis sarothroides whole allergenic extract is used in allergenic testing.
Approved
Racepinephrine
Racepinephrine is a racemic mixture consisting of d-DB00668 and l-DB00668 enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and shortness of breath. It is an active ingredient in...
Approved
Matched Description: … Epinephrine is a non-selective α- and β-adrenergic receptor agonist. ... Racepinephrine is a racemic mixture consisting of d-[DB00668] and l-[DB00668] enantiomers. ... It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including …
Ublituximab
CD20, an antigen expressed by various B and T cells, is an attractive therapeutic target in various cancers and autoimmune conditions.[A244195, A244200, A244205] Monoclonal antibodies for B cell depletion rely on their binding affinity and ability to clear bound cells through mechanisms such as antibody-dependent cellular cytotoxicity (ADCC), mediated by...
Approved
Investigational
Matched Description: … one-hour infusion twice-a-year following the starting dose. ... a unique epitope and enhance ADCC compared to other approved anti-CD20 antibodies such as [rituximab ... first and only anti-CD20 monoclonal antibody for multiple sclerosis allowing for administration in a …
Streptococcus pneumoniae type 2 capsular polysaccharide antigen
Streptococcus pneumoniae type 2 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 2 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 2 capsular polysaccharide antigen is a vaccine that contains highly purified …
Streptococcus pneumoniae type 6b capsular polysaccharide antigen
Streptococcus pneumoniae type 6b capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 6b of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 6b capsular polysaccharide antigen is a vaccine that contains highly purified …
Streptococcus pneumoniae type 7f capsular polysaccharide antigen
Streptococcus pneumoniae type 7f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 7f of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 7f capsular polysaccharide antigen is a vaccine that contains highly purified …
Streptococcus pneumoniae type 9v capsular polysaccharide antigen
Streptococcus pneumoniae type 9v capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 9v of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 9v capsular polysaccharide antigen is a vaccine that contains highly purified …
Streptococcus pneumoniae type 20 capsular polysaccharide antigen
Streptococcus pneumoniae type 20 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 20 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 20 capsular polysaccharide antigen is a vaccine that contains highly purified …
Interferon gamma-1b
Human Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purification of the product is achieved by conventional column chromatography.
The sequence displayed is a cDNA sequence which...
Approved
Investigational
Matched Description: … Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium ... The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray …
Displaying drugs 3751 - 3775 of 11778 in total