Displaying drugs 5001 - 5025 of 11638 in total
Varespladib
Varespladib has been investigated for the treatment and prevention of Sickle Cell Disease, Vaso-occlusive Crisis, and Acute Coronary Syndrome.
Investigational
Matched Categories: … Phospholipases A, antagonists & inhibitors …
Bromopyruvate
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
CIGB-258 peptide
CIGB-258 is a peptide that is immunoregulatory and derived from heat shock protein 60 of the cellular variant. As of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens...
Investigational
Matched Description: … CIGB-258 is a peptide that is immunoregulatory and derived from heat shock protein 60 of the cellular …
OSI-930
OSI-930 is an orally active inhibitor of two clinically validated targets: c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2). OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors. In preclinical studies, OSI-930 shows broad efficacy in tumor models representative of small...
Investigational
Gavestinel
Highly potent and selective non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM). Gavestinel displays > 1000-fold selectivity over NMDA, AMPA and kainate binding sites and is orally bioavailable and active in vivo.
Investigational
INH-A21
INH-A21 is a human staphylococcal immunoglobulin
Investigational
Matched Description: … INH-A21 is a human staphylococcal immunoglobulin …
Mucuna pruriens seed
Mucuna pruriens seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Mucuna pruriens seed is a plant/plant extract used in some OTC (over-the-counter) products. …
Triazavirin
Triazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy against influenza A and B, including the H5N1 strain.[A191709,A191625,A191916] It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications. Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating...
Experimental
Matched Description: … against influenza A and B, including the H5N1 strain. ... Triazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy …
Dipicolinic acid
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Atrasentan
Atrasentan is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called endothelin-1 protein receptor antagonists. It is a novel, selective endothelin A receptor antagonist (SERA).
Investigational
Matched Description: … It is a novel, selective endothelin A receptor antagonist (SERA). ... Atrasentan is a substance that is being studied in the treatment of cancer. …
Matched Categories: … Endothelin A Receptor Antagonists …
Matched Categories: … Endothelin A Receptor Antagonists …
Temefos
Diphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria.
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
AVA-4746
Investigational
1,N6-Ethenoadenine
Experimental
4-Amino-5-Hydroxymethyl-2-Methylpyrimidine
Experimental
Isoformononetin
Experimental
Allantoate
Experimental
3-isobutyl-1-methyl-7H-xanthine
Experimental
Dinitrochlorobenzene
Dinitrochlorobenzene has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Dasiprotimut-T
Dasiprotimut-T is a personalized therapeutic vaccine against B-cell lymphomas. It has been investigated in clinical trials.
Investigational
Matched Description: … Dasiprotimut-T is a personalized therapeutic vaccine against B-cell lymphomas. …
AAV9/MFSD8
AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Description: … AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. …
Tetrathiomolybdate
Tetrathiomolybdate is an oral, small-molecule, anticopper agent that is highly specific for lowering the levels of free copper in serum. COPREXA has completed pivotal clinical trials for the treatment of neurologic Wilson's disease. It is also developed for fibrotic disorders based upon the rationale that the fibrotic disease process is...
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Coumarin 120
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Conatumumab
Conatumumab has been used in trials studying the treatment of Sarcoma, Lymphoma, Oncology, Colon Cancer, and Rectal Cancer, among others.
Investigational
Cobitolimod
Cobitolimod is under investigation in clinical trial NCT03178669 (The Efficacy of Cobitolimod in Patients With Moderate to Severe Active Ulcerative Colitis).
Investigational
Taurochenodeoxycholic acid
Taurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile. As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile...
Experimental
Matched Iupac: … 4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to ... As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to ... As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 5001 - 5025 of 11638 in total