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Displaying drugs 601 - 625 of 15298 in total

Chlorambucil

A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Synonyms: … 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid ... γ-[p-di(2-chloroethyl)aminophenyl]butyric acid ... N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid …
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid …
Matched Description: … A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant ... in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). ... Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen …
Matched Products: … ลูเคอแรน (เม็ด 2 มก.) ... Leukeran 2 mg - Filmtabletten ... LEUKERAN 2 MG TABLET, 25 ADET …

Cortisone acetate

Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.[A226300,L13203] Cortisone acetate...
Approved
Investigational
Matched Iupac: … ,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate ... 2-[(1R,3aS,3bS,9aR,9bS,11aS)-1-hydroxy-9a,11a-dimethyl-7,10-dioxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH …
Matched Description: … Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. ... [A226295] Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory …
Matched Categories: … Corticosteroids for Systemic Use …

Varicella zoster vaccine (live/attenuated)

Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals 12 months of age and older. While the two vaccines contain the same immunological components and provide protection...
Approved
Matched Synonyms: … Human herpesvirus 3 live (attenuated) antigen …
Matched Description: … in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals ... Risk factors for developing shingles include old age, with rates increasing substantially in person's ... Clinical trials for Shingrix have shown greater than 90% efficacy in adults aged 50 and older, with 89% …
Matched Mixtures name: … Priorix - Tetra Pulver in einer Durchstechflasche und Lösungsmittel in einer Fertigspritze zur Herstellung …
Matched Categories: … Antiinfectives for Systemic Use …
Matched Products: … VARIVAX Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze ... Varilrix Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze …

Tetracaine

Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Synonyms: … 2-(dimethylamino)ethyl 4-(butylamino)benzoate ... 2-(Dimethylamino)ethyl p-(butylamino)benzoate ... p-Butylaminobenzoyl-2-dimethylaminoethanol …
Matched Iupac: … 2-(dimethylamino)ethyl 4-(butylamino)benzoate …
Matched Description: … Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Anesthetics for Topical Use …
Matched Products: … TETRACAINE HYDROCHLORIDE 0.5% OPHTHALMIC SOLUTION 2 ML ... Blt 3 ... FranklyNumb 3 …

Imipramine

Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Synonyms: … 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine ... 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … In depressed individuals, imipramine exerts a positive effect on mood. ... receptors, α1-adrenergic receptors and muscarinic receptors, which accounts for ... Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Antidepressive Agents Indicated for Depression ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index …
Matched Products: … SILEDX-3 …

Tolazamide

A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Synonyms: … 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea ... 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Matched Description: … A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide. …
Matched Categories: … Drugs Used in Diabetes …

Liotrix

Liotrix is a synthetically derived thyroid hormone replacement preparation. It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. Liotrix was developed when it was believed that serum levels of both T4 and T3 were maintained by direct thyroidal secretion....
Approved
Matched Iupac: … disodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate (2S)-2-amino-3-[ ... 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate …
Matched Description: … Administration of levothyroxine alone is sufficient for maintaining serum T4 and T3 levels in most patients ... In fact, administration of T3 may result in supratherapeutic levels of T3. ... a 4 to 1 ratio by weight. …

Polyquaternium-10 (400 cps at 2%)

Polyquaternium-10 is a quaternized hydroxyethyl cellulose and a polycationic polymer. It is commonly found in cosmetics and personal care products to mainly reduce static electricity and form films.
Approved
Matched Name: … Polyquaternium-10 (400 cps at 2%) …
Matched Description: … Polyquaternium-10 is a quaternized hydroxyethyl cellulose and a polycationic polymer. ... It is commonly found in cosmetics and personal care products to mainly reduce static electricity and …

Cetuximab

Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of epidermal growth factor (EGF). EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible...
Approved
Matched Description: … [A227963] Approved by the FDA in February 2004 under the brand name ERBITUX, cetuximab is used for ... [A227963] EGFR is often mutated in certain types of cancer and serves as a driver of tumorigenesis. ... [A227973] EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour …
Matched Products: … ERBITUX 5MG/ML SOLUTION FOR INFUSION …

Tacrolimus

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Iupac: … ]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo ... (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl …
Matched Description: … It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory ... It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria ... This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL-2 …
Matched Salts cas: … 109581-93-3 …
Matched Categories: … Medications that reduce magnesium levels ... Agents for Dermatitis, Excluding Corticosteroids ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Products: … Tacrolimus 0.1% In Pseudocatalase ... PROGRAF CONCENTRATE FOR INFUSION 5MG/ML ... PROGRAF CONCENTRATE FOR INFUSION 5 mg/ml …

Interferon alfa-n1

Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational
Matched Description: … Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least …

Betiatide

Approved
Experimental
Matched Iupac: … 2-(2-{2-[2-(benzoylsulfanyl)acetamido]acetamido}acetamido)acetic acid …
Matched Products: … Kit for the Preparation of Technetium Tc99m Mertiatide ... Technescan MAG 3 ... TECHNESCAN MAG 3 DRN 4334 …

Dexibuprofen

Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a...
Approved
Investigational
Matched Synonyms: … (2S)-2-(4-isobutylphenyl)propanoic acid ... (S)-α-methyl-4-(2-methylpropyl)benzeneacetic acid …
Matched Iupac: … (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with ... It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties ... For Metabolism, Enzymes, Carriers, Transporters Sections, refer to [Ibuprofen]. …
Matched Categories: … Non COX-2 selective NSAIDS …

Influenza A virus A/Victoria/4897/2022 IVR-238 (H1N1) Antigen (propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Victoria/4897/2022 IVR-238 (H1N1) Antigen (propiolactone inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection …
Matched Categories: … Inactivated Influenza A Virus Vaccine …

Sodium phosphate, dibasic, unspecified form

Approved
Experimental
Matched Mixtures name: … Aminosyn II in Dextrose ... Medline Saline Laxative For Children ... FLEET READY-TO-USE ENEMA FOR CHILDREN …

Pantothenic acid

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Iupac: … 3-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]propanoic acid …
Matched Description: … For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A ... Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered ... Williams in 1919. …
Matched Salts cas: … 867-81-2 …
Matched Mixtures name: … For-2 ... FLAVETTES DAILY PLUS TABLET F/C ... Toni Com Liq …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Nilutamide

Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate the growth of...
Approved
Investigational
Matched Synonyms: … 5,5-Dimethyl-3-(α,α,α-trifluoro-4-nitro-m-tolyl)hydantoin …
Matched Iupac: … 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione …
Matched Description: … Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen ... Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. …

Tea leaf

Tea leaf allergenic extract is used in allergenic testing.
Approved
Investigational
Matched Description: … Tea leaf allergenic extract is used in allergenic testing. …

Abatacept

Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … Although approved for the treatment of rheumatoid arthritis, Repligen has entered a slightly different ... It is produced through recombinant DNA technology in mammalian CHO cells. ... [L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight …
Matched Categories: … Agents reducing cytokine levels ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … ORENCIA Injection 125mg/ml in Prefilled Syringe …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Iupac: … 2-(chloromethyl)oxirane; prop-2-en-1-amine …
Matched Description: … Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Sevelamer Carbonate for Oral Suspension ... RENALAMER CO3 800 MG FILM TABLET, 180 ADET ... Sevelamer Carbonate For Oral Suspension …

Zinc

A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Description: … /ZnT8_ may increase susceptibility to type 2 diabetes provided novel insights into the role of zinc in ... It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an ... zinc homeostasis is, therefore, imperative to the development of preventive and treatment regimens for …
Matched Mixtures name: … Vitamin E + 3 Extra Strength With Zinc ... For-2 ... Zinc Lozenges With Vitamin C In A Nonmedicinal Base With Echinacea Lozenge …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Port A Mins Super Zinc 15 ... Port A Mins Super Zinc 30 …

Tenecteplase

Tenecteplase is a tissue plasminogen activator (tPA) developed from modifications of natural human tPA complementary DNA (cDNA). It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids...
Approved
Matched Description: … 299 in the protease domain. ... It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine ... Tenecteplase is a tissue plasminogen activator (tPA) developed from modifications of natural human tPA …
Matched Products: … METALYSE FOR INJECTION 10,000 u/vial …

Sulfathiazole

Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. Except for those formulated for vaginal use, the FDA withdrew its approval for the use of...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 2-Sulfonamidothiazole ... 2-Sulfanilamidothiazol ... 2-Sulfanilamidothiazole …
Matched Iupac: … 4-amino-N-(1,3-thiazol-2-yl)benzene-1-sulfonamide …
Matched Description: … Except for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products ... Sulfathiazole is a short-acting sulfa drug. ... It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Bromothalonil

Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and industrial products. It is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy . In 2005,...
Approved
Experimental
Matched Synonyms: … 2-Bromo-2-(bromomethyl) glutaronitrile ... 2-Bromo-2-(bromomethyl) pentanedinitrile ... Glutaronitrile, 2-bromo-2-(bromomethyl)- …
Matched Iupac: … 2-bromo-2-(bromomethyl)pentanedinitrile …
Matched Description: … It is also a known allergen and dermatological irritant that has been banned in many EU countries due ... In 2005, MDBGN was named in the top 15 most frequently positive allergens identified in patch tests by ... Sensitivity to Bromothalonil may be identified with a clinical patch test. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Urokinase

Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase. Urokinase remains connected between these 2 chains by a sulfhydryl bond. Urokinase was granted FDA approval on 16 January 1978.
Approved
Investigational
Withdrawn
Matched Description: … [A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond. ... Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and …
Matched Products: … Kinlytic (urokinase for Injection) …
Displaying drugs 601 - 625 of 15298 in total