Displaying drugs 10951 - 10975 of 12185 in total
Huperzine B
Huperzine B is a novel acetylcholinesterase inhibitor.
Investigational
Matched Description: … Huperzine B is a novel acetylcholinesterase inhibitor. …
Isatoribine
Isatoribine is a selective agonist of TLR7.
Investigational
Matched Description: … Isatoribine is a selective agonist of TLR7. …
SU-11652
SU-11652 is a tyrosine kinase inhibitor.
Experimental
Matched Description: … SU-11652 is a tyrosine kinase inhibitor. …
BBP-711
BBP-711 is a glycolate oxidase inhibitor.
Investigational
Matched Description: … BBP-711 is a glycolate oxidase inhibitor. …
M1-c6v1
M1-c6v1 is a recombinant oncolytic virus.
Investigational
Matched Description: … M1-c6v1 is a recombinant oncolytic virus. …
Pafuramidine
Pafuramidine, a prodrug of furamidine, currently has orphan status for Pneumocystis jiroveci pneumonia.
Investigational
Matched Description: … Pafuramidine, a prodrug of furamidine, currently has orphan status for _Pneumocystis jiroveci_ pneumonia …
Stibophen
Stibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms.
Experimental
Matched Description: … Stibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms. …
BI-1206
BI-1206 is a fully human immunoglobulin G1 monoclonal antibody that targets CD32b.
Investigational
Matched Description: … BI-1206 is a fully human immunoglobulin G1 monoclonal antibody that targets CD32b. …
Serelaxin
Recombinant human relaxin is a hormone produced during pregnancy that facilitates the birth process by causing a softening and lengthening of the cervix and the pubic symphysis (the place where the pubic bones come together).It is a heterodimer protein secreted by the corpus luteum and placenta during pregnancy.
Investigational
Matched Description: … Recombinant human relaxin is a hormone produced during pregnancy that facilitates the birth process by ... causing a softening and lengthening of the cervix and the pubic symphysis (the place where the pubic ... bones come together).It is a heterodimer protein secreted by the corpus luteum and placenta during pregnancy …
Romifidine
Romifidine is a veterinary drug utilized as a sedative primarily in large animals, most frequently horses. It is also used less commonly in a wide variety of other animal species. This drug's chemical structure closely resembles that of clonidine, however, romifidine is not approved for use in humans.
Vet approved
Matched Description: … Romifidine is a veterinary drug utilized as a sedative primarily in large animals, most frequently horses ... It is also used less commonly in a wide variety of other animal species. …
Nebicapone
Nebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg).
Investigational
Matched Description: … Plus a Single-dose of Nebicapone 150 mg). ... clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a ... Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg …
Tenofovir exalidex
Tenofovir exalidex is under investigation in clinical trial NCT01080820 (A Safety, Tolerability and Pharmacokinetic Study of a Single Dose of CMX157 in Healthy Volunteers).
Investigational
Matched Description: … Study of a Single Dose of CMX157 in Healthy Volunteers). ... Tenofovir exalidex is under investigation in clinical trial NCT01080820 (A Safety, Tolerability and Pharmacokinetic …
CT-011
CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients with advanced haematological malignancies. It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities.
Investigational
Matched Description: … CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients …
REV131
rEV131 is in development for allergic rhinitis, asthma and several inflammatory eye diseases. It is a topically delivered small protein that acts as an anti-inflammatory agent.
Investigational
Matched Description: … It is a topically delivered small protein that acts as an anti-inflammatory agent. …
Sugemalimab
Sugemalimab is a fully human, full-length IgG4 monoclonal anti-PD-L1 antibody discovered by CStone Pharmaceuticals and being investigated against relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma (R/R ENKTL) in adult patients and T-cell lymphoma.[L32868, L32873] It has been granted the Breakthrough Therapy Designation by the FDA to treat R/R ENKTL...
Investigational
Matched Description: … Sugemalimab is a fully human, full-length IgG4 monoclonal anti-PD-L1 antibody discovered by CStone Pharmaceuticals ... [L32868] Sugemalimab is under investigation in clinical trial NCT03802591 (A Study of CS1001 in Subjects …
Topsalysin
Topsalysin is being developed for the treatment of localized prostate cancer and also benign prostatic hyperplasia. Topsalysin is delivered locally to the prostate under ultrasound guidance.
Investigational
Tifuvirtide
Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast-track designation from the FDA and is in Phase I/II clinical testing.
Investigational
Matched Description: … Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors …
Elsamitrucin
The cytostatic agent Elsamitrucin is a new fermentation product active in a variety of in vivo tumor models of murine and human origin. (PMID: 8150873)
Investigational
Matched Description: … The cytostatic agent Elsamitrucin is a new fermentation product active in a variety of in vivo tumor …
Milvexian
Milvexian is under investigation in clinical trial NCT03766581 (A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel).
Investigational
Matched Description: … of a Stroke in Patients Receiving Aspirin and Clopidogrel). ... Milvexian is under investigation in clinical trial NCT03766581 (A Study on BMS-986177 for the Prevention …
rhMBL
rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections in individuals with low levels of Mannose-Binding Lectin (MBL). Over 10 percent of the general population is estimated to be MBL-deficient. Natural MBL is a 400-700kDa oligomer made of 3 identical 32kDa peptide...
Investigational
Matched Description: … MBL forms different oligomers but must form at least a tetramer to be active. ... Natural MBL is a 400-700kDa oligomer made of 3 identical 32kDa peptide chains. ... rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections …
FP0011
FP0011 is a small molecule antiglutamatergic compound with symptomatic and disease modifying effects in a variety of neurological disorders (amyotrophic lateral sclerosis and Parkinson's disease). It acts on the presynaptic regulation of glutamate and shows strong neuroprotective properties.
Investigational
Matched Description: … FP0011 is a small molecule antiglutamatergic compound with symptomatic and disease modifying effects ... in a variety of neurological disorders (amyotrophic lateral sclerosis and Parkinson's disease). …
NN344
NN344 is a neutral, soluble long-acting human insulin analogue with 24 hour coverage by once daily injection. NN344 has a very flat and predictable action profile. The product is intended for basal insulin treatment of diabetes mellitus.
Investigational
Matched Description: … NN344 has a very flat and predictable action profile. ... NN344 is a neutral, soluble long-acting human insulin analogue with 24 hour coverage by once daily injection …
RAV12
RAV12 is investigated for use/treatment in solid tumors. RAV12 is a solid. RAV12 is a chimeric antibody that recognizes RAAG12, an N-linked carbohydrate antigen found on gastric, colon, pancreatic, prostate, ovarian, breast, and kidney cancer cells.
Investigational
Matched Description: … RAV12 is a solid. ... RAV12 is a chimeric antibody that recognizes RAAG12, an N-linked carbohydrate antigen found on gastric …
KD7040
KD7040 is a topically-delivered inducible nitric oxide synthase (iNOS) inhibitor for the treatment of neuropathic pain. The KD7040 IND was filed in 4Q06, and a Phase Ib clinical trial began 2Q07. It is being developed by Kalypsys.
Investigational
Matched Description: … The KD7040 IND was filed in 4Q06, and a Phase Ib clinical trial began 2Q07. ... KD7040 is a topically-delivered inducible nitric oxide synthase (iNOS) inhibitor for the treatment of …
Bradanicline
Bradanicline, a novel small molecule that modulates the activity of the neuronal nicotinic receptor (NNR) subtype known as alpha7(α7). Bradanicline belongs to a new class of drugs for the treatment of central nervous system diseases and disorders.
Investigational
Matched Description: … Bradanicline, a novel small molecule that modulates the activity of the neuronal nicotinic receptor ( ... Bradanicline belongs to a new class of drugs for the treatment of central nervous system diseases and …
Displaying drugs 10951 - 10975 of 12185 in total