Displaying drugs 15101 - 15125 of 15438 in total
Pexmetinib
Pexmetinib is under investigation in clinical trial NCT04074967 (Study of ARRY-614 Plus Either Nivolumab or Ipilimumab).
Investigational
Matched Iupac: … 3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-[(5-fluoro-2-{[1-(2-hydroxyethyl)-1H-indazol-5- …
Matched Description: … Pexmetinib is under investigation in clinical trial NCT04074967 (Study of ARRY-614 Plus Either Nivolumab …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Pexmetinib is under investigation in clinical trial NCT04074967 (Study of ARRY-614 Plus Either Nivolumab …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Rilematovir
Rilematovir is under investigation in clinical trial NCT04056611 (Effects of JNJ-53718678 in Adult and Adolescent Participants Who Had a Hematopoietic Stem Cell Transplantation and Who Are Infected With Respiratory Syncytial Virus (RSV)).
Investigational
Matched Iupac: … [4,5-c]pyridin-2-one ... 3-{[5-chloro-1-(3-methanesulfonylpropyl)-1H-indol-2-yl]methyl}-1-(2,2,2-trifluoroethyl)-1H,2H,3H-imidazo …
Matched Description: … Rilematovir is under investigation in clinical trial NCT04056611 (Effects of JNJ-53718678 in Adult and ... Adolescent Participants Who Had a Hematopoietic Stem Cell Transplantation and Who Are Infected With …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Rilematovir is under investigation in clinical trial NCT04056611 (Effects of JNJ-53718678 in Adult and ... Adolescent Participants Who Had a Hematopoietic Stem Cell Transplantation and Who Are Infected With …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Miricorilant
Miricorilant is under investigation in clinical trial NCT03818256 (Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients With Schizophrenia and Recent Weight Gain While Taking Antipsychotic Medications (GRATITUDE)).
Investigational
Matched Iupac: … 6-[(1r,4r)-4-phenylcyclohexyl]-5-{[3-(trifluoromethyl)phenyl]methyl}-1,2,3,4-tetrahydropyrimidine-2,4 …
Matched Description: … Miricorilant is under investigation in clinical trial NCT03818256 (Study Evaluating the Safety, Efficacy ... , and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients With Schizophrenia and Recent …
Matched Description: … Miricorilant is under investigation in clinical trial NCT03818256 (Study Evaluating the Safety, Efficacy ... , and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients With Schizophrenia and Recent …
XL418
XL418 is a novel anticancer compound.
Investigational
Matched Description: … XL418 is a novel anticancer compound. …
Pardoprunox
Pardoprunox has been used in trials studying the treatment of Early Stage Parkinson's Disease and Advanced Stage Parkinson's Disease. Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.
Investigational
Matched Iupac: … 7-(4-methylpiperazin-1-yl)-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Description: … Pardoprunox has been used in trials studying the treatment of Early Stage Parkinson's Disease and Advanced ... Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Pardoprunox has been used in trials studying the treatment of Early Stage Parkinson's Disease and Advanced ... Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sphingosine
An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
Experimental
Matched Iupac: … (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol …
Matched Description: … An amino alcohol with a long unsaturated hydrocarbon chain. ... Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. …
Matched Description: … An amino alcohol with a long unsaturated hydrocarbon chain. ... Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. …
Bafetinib
Bafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult Glioblastoma, Chronic Myeloid Leukemia, and Acute Lymphocytic Leukemia, among others.
Investigational
Matched Iupac: … N-[3-({[4,5'-bipyrimidin]-2-yl}amino)-4-methylphenyl]-4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]methyl ... }-3-(trifluoromethyl)benzamide …
Matched Description: … Bafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult …
Matched Description: … Bafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult …
Savolitinib
Savolitinib has been used in trials studying the treatment and health services research of Tumor, Food Effect, Gastric Cancer, Health Subjects, and Colorectal Cancer, among others.
Investigational
Matched Iupac: … 4-{1-[(1S)-1-{imidazo[1,2-a]pyridin-6-yl}ethyl]-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl}-1-methyl-1H-pyrazole …
Matched Description: … Savolitinib has been used in trials studying the treatment and health services research of Tumor, Food …
Matched Description: … Savolitinib has been used in trials studying the treatment and health services research of Tumor, Food …
Polmacoxib
Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee.
Investigational
Matched Iupac: … 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl]benzene-1-sulfonamide …
Matched Description: … Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Description: … Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Rebastinib
Rebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. It is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent.
Investigational
Matched Iupac: … -2-carboxamide ... 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine …
Matched Description: … Rebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Rebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bicuculline
Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.
Experimental
Matched Iupac: … 2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3,5,11-trioxatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2( …
Matched Description: … Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. ... It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria …
Matched Categories: … GABA-A Receptor Antagonists ... Heterocyclic Compounds, 2-Ring …
Matched Description: … Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. ... It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria …
Matched Categories: … GABA-A Receptor Antagonists ... Heterocyclic Compounds, 2-Ring …
BMS-986104
BMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986104 in Healthy Male Subjects).
Investigational
Matched Iupac: … [(1R,3S)-1-amino-3-[(6R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl]cyclopentyl]methanol …
Matched Description: … BMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind ... Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986104 in …
Matched Description: … BMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind ... Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986104 in …
Lucitanib
Lucitanib has been used in trials studying the treatment of ER+, MBC, SCLC, HER2+, and NSCLC, among others.
Investigational
Matched Description: … Lucitanib has been used in trials studying the treatment of ER+, MBC, SCLC, HER2+, and NSCLC, among others …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Burixafor
Burixafor has been used in trials studying the treatment of Multiple Myeloma, Hodgkin's Disease, and Non-hodgkin's Lymphoma.
Investigational
Matched Iupac: … (2-{4-[6-amino-2-({[(1r,4r)-4-({[3-(cyclohexylamino)propyl]amino}methyl)cyclohexyl]methyl}amino)pyrimidin …
Matched Description: … Burixafor has been used in trials studying the treatment of Multiple Myeloma, Hodgkin's Disease, and …
Matched Description: … Burixafor has been used in trials studying the treatment of Multiple Myeloma, Hodgkin's Disease, and …
Letaxaban
Letaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and Acute Coronary Syndrome.
Investigational
Matched Iupac: … 1-{1-[(2S)-3-[(6-chloronaphthalen-2-yl)sulfonyl]-2-hydroxypropanoyl]piperidin-4-yl}-1,3-diazinan-2-one …
Matched Description: … Letaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and …
Matched Description: … Letaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and …
PF-03463275
PF-03463275 has been used in trials studying the treatment of Schizophrenia and Cognitive Impairments Associated With Schizophrenia.
Investigational
Matched Iupac: … N-[(3-chloro-4-fluorophenyl)methyl]-1-methyl-N-{[(1R,5S,6S)-3-methyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl …
Matched Description: … PF-03463275 has been used in trials studying the treatment of Schizophrenia and Cognitive Impairments …
Matched Description: … PF-03463275 has been used in trials studying the treatment of Schizophrenia and Cognitive Impairments …
Recoflavone
Recoflavone has been used in trials studying the treatment of Acute Gastritis, Dry Eye Syndrome, and Chronic Gastritis.
Investigational
Matched Iupac: … 2-{[2-(3,4-dimethoxyphenyl)-5-methoxy-4-oxo-4H-chromen-7-yl]oxy}acetic acid …
Matched Description: … Recoflavone has been used in trials studying the treatment of Acute Gastritis, Dry Eye Syndrome, and …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Recoflavone has been used in trials studying the treatment of Acute Gastritis, Dry Eye Syndrome, and …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Veledimex
Veledimex has been used in trials studying the treatment of Glioblastoma Multiforme, Metastatic Breast Cancer, and Anaplastic Oligoastrocytoma.
Investigational
Matched Iupac: … N'-(3,5-dimethylbenzoyl)-N'-[(3R)-2,2-dimethylhexan-3-yl]-2-ethyl-3-methoxybenzohydrazide …
Matched Description: … Veledimex has been used in trials studying the treatment of Glioblastoma Multiforme, Metastatic Breast …
Matched Description: … Veledimex has been used in trials studying the treatment of Glioblastoma Multiforme, Metastatic Breast …
GSK-424887
Gsk424887 has been used in trials studying the basic science and treatment of Depressive Disorder and Anxiety Disorder.
Investigational
Matched Iupac: … N-[(1S)-1-(3-chloronaphthalen-1-yl)ethyl]-2-[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]-N-methylacetamide …
Matched Description: … Gsk424887 has been used in trials studying the basic science and treatment of Depressive Disorder and …
Matched Description: … Gsk424887 has been used in trials studying the basic science and treatment of Depressive Disorder and …
Liothyronine I-131
Liothyronine I-131 has been used in trials studying the treatment of Tricuspid Atresia and Heart Defects, Congenital.
Investigational
Matched Iupac: … (2S)-2-amino-3-{4-[4-hydroxy-3-(¹³¹I)iodophenoxy]-3,5-di(¹³¹I)iodophenyl}propanoic acid …
Matched Description: … Liothyronine I-131 has been used in trials studying the treatment of Tricuspid Atresia and Heart Defects …
Matched Description: … Liothyronine I-131 has been used in trials studying the treatment of Tricuspid Atresia and Heart Defects …
Nepadutant
Nepadutant has been used in trials studying the treatment of Colic, Infantile Colic, and Infantile Functional Gastrointestinal Disorders.
Investigational
Matched Iupac: … 2-[(1S,4S,7S,10S,13S,16S)-4-benzyl-7-[(1H-indol-3-yl)methyl]-16-(2-methylpropyl)-3,6,9,12,15,18,21-heptaoxo ... -6-(hydroxymethyl)oxan-2-yl]acetamide ... -2,5,8,11,14,17,20-heptaazabicyclo[8.8.4]docosan-13-yl]-N-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy …
Matched Description: … Nepadutant has been used in trials studying the treatment of Colic, Infantile Colic, and Infantile Functional …
Matched Description: … Nepadutant has been used in trials studying the treatment of Colic, Infantile Colic, and Infantile Functional …
Tecemotide
Tecemotide has been used in trials studying the treatment of Prostate Cancer and Carcinoma, Non-Small-Cell Lung.
Investigational
Matched Description: … Tecemotide has been used in trials studying the treatment of Prostate Cancer and Carcinoma, Non-Small-Cell …
Tonapofylline
Tonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and Congestive Heart Failure.
Investigational
Matched Iupac: … 3-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)bicyclo[2.2.2]octan-1-yl]propanoic acid …
Matched Description: … Tonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Tonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sivelestat
Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult.
Investigational
Matched Iupac: … 2-[(2-{4-[(2,2-dimethylpropanoyl)oxy]benzenesulfonamido}phenyl)formamido]acetic acid …
Matched Description: … Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress …
Matched Description: … Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress …
GS-9256
GS-9256 has been used in trials studying the treatment of HCV Infection and Chronic Hepatitis C Infection.
Investigational
Matched Iupac: … [(1S,4S,6R,14S,18R)-18-[(8-chloro-7-methoxy-2-{2-[(propan-2-yl)amino]-1,3-thiazol-4-yl}quinolin-4-yl) …
Matched Description: … GS-9256 has been used in trials studying the treatment of HCV Infection and Chronic Hepatitis C Infection …
Matched Description: … GS-9256 has been used in trials studying the treatment of HCV Infection and Chronic Hepatitis C Infection …
Displaying drugs 15101 - 15125 of 15438 in total