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Displaying drugs 15176 - 15200 of 15339 in total

4-isothioureidobutyronitrile

Thioureidobutyronitrile has been used in trials studying the treatment of Solid Tumors and Ovarian cancer.
Investigational
Matched Description: … Thioureidobutyronitrile has been used in trials studying the treatment of Solid Tumors and Ovarian cancer …

Pruvanserin

Pruvanserin has been used in trials studying the treatment of Sleep Initiation and Maintenance Disorders.
Investigational
Matched Iupac: … 7-{4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl}-1H-indole-3-carbonitrile …
Matched Description: … Pruvanserin has been used in trials studying the treatment of Sleep Initiation and Maintenance Disorders …

Tarloxotinib

Tarloxotinib is under investigation in clinical trial NCT03743350 (NSCLC Exon 20 or HER2-activating Mutations).
Investigational
Matched Iupac: … [(2E)-3-({4-[(3-bromo-4-chlorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}carbamoyl)prop-2-en-1-yl]dimethyl …
Matched Description: … Tarloxotinib is under investigation in clinical trial NCT03743350 (NSCLC Exon 20 or HER2-activating Mutations …

PF-04991532

PF-04991532 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Glucose Metabolism Disorders.
Investigational
Matched Iupac: … 6-[(2S)-3-cyclopentyl-2-[4-(trifluoromethyl)-1H-imidazol-1-yl]propanamido]pyridine-3-carboxylic acid …
Matched Description: … PF-04991532 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 Diabetes ... Mellitus, Diabetes Mellitus, Type 2, and Glucose Metabolism Disorders. …

Danirixin

Danirixin has been used in trials studying the treatment and basic science of Virus Diseases, Nutritional Status, Pulmonary Disease, Chronic Obstructive, and Infections, Respiratory Syncytial Virus.
Investigational
Matched Iupac: … 1-{4-chloro-2-hydroxy-3-[(3S)-piperidine-3-sulfonyl]phenyl}-3-(3-fluoro-2-methylphenyl)urea …
Matched Description: … Danirixin has been used in trials studying the treatment and basic science of Virus Diseases, Nutritional …

Tetrahydropalmatine

Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
Investigational
Matched Description: … Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia ... With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal …

Taselisib

Taselisib has been used in trials studying the treatment and basic science of LYMPHOMA, Breast Cancer, Ovarian Cancer, Solid Neoplasm, and HER2/Neu Negative, among others.
Investigational
Matched Iupac: … 2-methyl-2-(4-{4-[3-methyl-1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-9-oxa-3,6-diazatricyclo[8.4.0.0^{2,6 …
Matched Description: … Taselisib has been used in trials studying the treatment and basic science of LYMPHOMA, Breast Cancer …
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …

Sapitinib

Sapitinib has been used in trials studying the treatment and basic science of Neoplasms, Breast Cancer, Breast Neoplasms, Metastatic Cancer, and Metastatic Breast Cancer, among others.
Investigational
Matched Iupac: … 2-[4-({4-[(3-chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)piperidin-1-yl]-N-methylacetamide …
Matched Description: … Sapitinib has been used in trials studying the treatment and basic science of Neoplasms, Breast Cancer …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Nalorphine

Nalorphine is a mixed opioid agonist–antagonist. It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Experimental
Vet approved
Matched Iupac: … (1S,5R,13R,14S,17R)-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid ... Nalorphine is a mixed opioid agonist–antagonist. …

Tofimilast

Tofimilast has been used in trials studying the treatment of Asthma and Pulmonary Disease, Chronic Obstructive.
Investigational
Matched Iupac: … 12-cyclopentyl-10-ethyl-5-(thiophen-2-yl)-3,4,6,11,12-pentaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,10 …
Matched Description: … Tofimilast has been used in trials studying the treatment of Asthma and Pulmonary Disease, Chronic Obstructive …

ORM-12741

ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … (2S,3S)-3-(methoxymethyl)-3-methyl-17-oxa-7-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(10),11,13,15 …
Matched Description: … ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Antagonists …

Perzinfotel

Perzinfotel has been used in trials studying the treatment of Diabetes Mellitus and Diabetic Neuropathy, Painful.
Investigational
Matched Iupac: … (2-{8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl}ethyl)phosphonic acid …
Matched Description: … Perzinfotel has been used in trials studying the treatment of Diabetes Mellitus and Diabetic Neuropathy …

Sonedenoson

Sonedenoson has been used in trials studying the treatment of Foot Ulcer, Diabetic and Diabetes Complications.
Investigational
Matched Iupac: … (2R,3R,4S,5R)-2-{6-amino-2-[2-(4-chlorophenyl)ethoxy]-9H-purin-9-yl}-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Description: … Sonedenoson has been used in trials studying the treatment of Foot Ulcer, Diabetic and Diabetes Complications …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

BI-671800

Bi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial.
Investigational
Matched Iupac: … 2-[4,6-bis(dimethylamino)-2-({4-[4-(trifluoromethyl)benzamido]phenyl}methyl)pyrimidin-5-yl]acetic acid …
Matched Description: … Bi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial. …

Taprenepag

Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.
Investigational
Matched Iupac: … 2-{3-[(N-{[4-(1H-pyrazol-1-yl)phenyl]methyl}pyridine-3-sulfonamido)methyl]phenoxy}acetic acid …
Matched Description: … Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle …
Matched Categories: … Receptors, Prostaglandin E, EP2 Subtype, agonists …

Nerispirdine

Nerispirdine has been used in trials studying the treatment of Neuritis, Optic Nerve, and Multiple Sclerosis.
Investigational
Matched Iupac: … N-(3-fluoropyridin-4-yl)-3-methyl-N-propyl-1H-indol-1-amine …
Matched Description: … Nerispirdine has been used in trials studying the treatment of Neuritis, Optic Nerve, and Multiple Sclerosis …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Mitolactol

Mitolactol has been used in trials studying the treatment of Brain and Central Nervous System Tumors.
Investigational
Matched Description: … Mitolactol has been used in trials studying the treatment of Brain and Central Nervous System Tumors. …

Konjac mannan

Konjac mannan is under investigation in clinical trial NCT01709955 (The Effects of Glucomannan on Weight Loss).
Investigational
Matched Description: … Konjac mannan is under investigation in clinical trial NCT01709955 (The Effects of Glucomannan on Weight …

GsMtx-4

GsMtx-4 is a peptide found in tarantula venom that inhibits mechanosensitive ion channel (MSC) activity.
Investigational
Matched Description: … GsMtx-4 is a peptide found in tarantula venom that inhibits mechanosensitive ion channel (MSC) activity …

Staurosporine

An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Experimental
Matched Iupac: … (2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28 …
Matched Description: … An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses ... in human neuroblastoma cells. ... (Biochem Biophys Res Commun 1995;214(3):1114-20) …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …

Gevokizumab

Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others. Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of...
Investigational
Matched Description: … Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. ... It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. ... Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's …

LNP-nCoVsaRNA Vaccine

LNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV-2, which is used primarily by the virus to attach to and invade human cells. The vaccine was developed in and tested by the Medical Research Council Clinical Trials Unit at UCL in the UK, and jointly...
Investigational
Matched Description: … -2, which is used primarily by the virus to attach to and invade human cells. ... The vaccine was developed in and tested by the Medical Research Council Clinical Trials Unit at UCL in ... LNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV …

TMC-649128

TMC-649128 is under investigation in clinical trial NCT01391117 (TMC649128HPC1002 - a Trial inGenotype 1 Hepatitis C Virus (HCV) - Infected Participants to Determine the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of TMC649128, Alone and Combined With Pegylated Interferon + Ribavirin).
Investigational
Matched Iupac: … [(2R,3S,4S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-2-azido-4-methyl-3-[(2-methylpropanoyl)oxy ... ]oxolan-2-yl]methyl 2-methylpropanoate …
Matched Description: … TMC-649128 is under investigation in clinical trial NCT01391117 (TMC649128HPC1002 - a Trial inGenotype ... 1 Hepatitis C Virus (HCV) - Infected Participants to Determine the Safety, Tolerability, Pharmacokinetics …

Mavoglurant

Mavoglurant has been used in trials studying the treatment of Patient Diagnosed With OCD and and Resistant to SSRI Treatment (Failed SSRI Over 12 Weeks at Appropriate Doses).
Investigational
Matched Iupac: … methyl (3aR,4S,7aR)-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-octahydro-1H-indole-1-carboxylate …
Matched Description: … Mavoglurant has been used in trials studying the treatment of Patient Diagnosed With OCD and and Resistant …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

QAV-680

QAV680 has been used in trials studying the treatment of Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis.
Investigational
Matched Iupac: … 2-{1-[(4-methanesulfonylphenyl)methyl]-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}acetic acid …
Matched Description: … QAV680 has been used in trials studying the treatment of Asthma, Allergic Rhinitis, and Seasonal Allergic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 15176 - 15200 of 15339 in total