Displaying drugs 6326 - 6350 of 6831 in total
Bradykinin
Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.
Investigational
Matched Iupac: … phenylpropanamido]-3-hydroxypropanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanamido]-5-carbamimidamidopentanoic ... (2S)-2-amino-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}acetamido)-3- …
Onalespib
Investigational
Matched Iupac: … 4-{5-[(4-methylpiperazin-1-yl)methyl]-2,3-dihydro-1H-isoindole-2-carbonyl}-6-(propan-2-yl)benzene-1,3 …
Orotic acid
Investigational
Matched Iupac: … 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid …
Chlorotoxin I-131
Chlorotoxin I-131 is investigated in clinical trials for treating brain cancer. Chlorotoxin I-131 binds to and reduces the activity of a matrix metalloproteinase (MMP) that regulates functioning of the chloride channels on cell membranes. Chlorotoxin is a small 36-amino-acid peptide that selectively binds to glioma cells but not normal brain...
Investigational
Matched Iupac: … {2-[4-(1,2-diphenylbutyl)phenoxy]ethyl}dimethylamine …
Kynurenic Acid
Kynurenic Acid is under investigation in clinical trial NCT02340325 (FS2 Safety and Tolerability Study in Healthy Volunteers).
Investigational
Matched Iupac: … 4-oxo-1,4-dihydroquinoline-2-carboxylic acid …
Remetinostat
Remetinostat is under investigation in clinical trial NCT02213861 (Efficacy, Safety and Tolerability Study of SHAPE in IA, IB or IIA Cutaneous T-cell Lymphoma).
Investigational
Matched Iupac: … methyl 4-{[7-(hydroxycarbamoyl)heptanoyl]oxy}benzoate …
Ampreloxetine
Ampreloxetine is under investigation in clinical trial NCT03750552 (Clinical Effect of TD-9855 for Treating snOH in Subjects With Primary Autonomic Failure).
Investigational
Matched Iupac: … 4-{2-[(2,4,6-trifluorophenoxy)methyl]phenyl}piperidine …
Ethylmethylthiambutene
Experimental
Illicit
Matched Iupac: … [4,4-bis(thiophen-2-yl)but-3-en-2-yl](ethyl)methylamine …
Misonidazole
Misonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole).
Investigational
Matched Iupac: … 1-methoxy-3-(2-nitro-1H-imidazol-1-yl)propan-2-ol …
Trofosfamide
Trofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors.
Investigational
Matched Iupac: … 2-[bis(2-chloroethyl)amino]-3-(2-chloroethyl)-1,3,2lambda5-oxazaphosphinan-2-one …
Alvelestat
Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … )phenyl]-1,2-dihydropyridine-3-carboxamide ... N-[(5-methanesulfonylpyridin-2-yl)methyl]-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-2-oxo-1-[3-(trifluoromethyl …
Fozivudine Tidoxil
Fozivudine Tidoxil has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Iupac: … )-3-(dodecylsulfanyl)propoxy]phosphinic acid ... {[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}[2-(decyloxy …
Florbenazine F-18
Florbenazine F-18 is under investigation in clinical trial NCT01515384 (A Trial of 18F-AV-133 Positron Emission Tomography (PET)).
Investigational
Matched Iupac: … (2R,3R,11bR)-9-[3-(¹⁸F)fluoropropoxy]-10-methoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1 …
MK-7145
MK-7145 has been used in trials studying the treatment of Hypertension and Renal Insufficiency.
Investigational
Matched Iupac: … 5-[(1R)-1-hydroxy-2-{4-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-1,3-dihydro-2-benzofuran-5-yl)ethyl]piperazin ... -1-yl}ethyl]-4-methyl-1,3-dihydro-2-benzofuran-1-one …
GS-9191
GS-9191 is under investigation in clinical trial NCT00499967 (Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts).
Investigational
Matched Iupac: … phenylpropan-2-yl]amino})phosphoryl]amino}-3-phenylpropanoate ... 2-{[({2-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]ethoxy}methyl)({[(2S)-1-(2-methylpropoxy)-1-oxo-3- …
MLN8054
MLN8054 has been used in trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and Advanced Malignancies.
Investigational
Matched Iupac: … -heptaen-4-yl]amino}benzoic acid ... 4-{[13-chloro-10-(2,6-difluorophenyl)-3,5,9-triazatricyclo[9.4.0.0^{2,7}]pentadeca-1(11),2,4,6,9,12,14 …
Matched Salts cas: … 869366-15-4 …
Matched Salts cas: … 869366-15-4 …
Satraplatin
Satraplatin is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy. As an investigation drug, it has not yet received U.S. Food and Drug Administration (FDA) approval and is not available in retail pharmacies.
Investigational
Matched Iupac: … platinum(4+) cyclohexanamine diacetate amine dichloride …
Gabexate
Gabexate is a synthetic serine protease inhibitor which has been used as an anticoagulant. It also known to decrease production of inflammatory cytokines. Gabexate has been investigated for use in cancer, ischemia-reperfusion injury, and pancreatitis.[A19218,A19219,A19220]
Investigational
Matched Iupac: … ethyl 4-[(6-carbamimidamidohexanoyl)oxy]benzoate …
Diperodon
Vet approved
Matched Iupac: … 2-[(phenylcarbamoyl)oxy]-3-(piperidin-1-yl)propyl N-phenylcarbamate …
Centanafadine
Centanafadine is under investigation in clinical trial NCT02827513 (A Phase 1 Study to Investigate the Safety, Tolerance, Food Effect, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of Extended Release Formulations of Centanafadine (CTN) in Young Healthy Subjects).
Investigational
Matched Iupac: … (1R,5S)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane …
Reproxalap
Reproxalap (previously ADX 102 or NS-2) is a small molecule inhibitor being developed by Aldeyra Therapeutics investigated against dry eye disease, allergic conjunctivitis, noninfectious anterior uveitis, and Sjögren-Larsson syndrome. NS-2 has orphan drug status due to it being investigated for treatment of Sjogren-Larsson syndrome.
Investigational
Matched Iupac: … 2-(3-amino-6-chloroquinolin-2-yl)propan-2-ol …
Landipirdine
Landipirdine is under investigation in clinical trial NCT02258152 (SYN120 Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)).
Investigational
Matched Iupac: … {[(1R)-6-(3-fluorobenzenesulfonyl)-1,2,3,4-tetrahydronaphthalen-1-yl]methyl}urea …
Selepressin
Selepressin has been used in trials studying the treatment of Septic Shock.
Investigational
Matched Iupac: … 2-{[(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-16-benzyl-13-[(2S)-butan-2-yl]-7-(carbamoylmethyl)-10-(3- ... carbamoylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl]pyrrolidin …
Pritelivir
Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.
Investigational
Matched Iupac: … N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2-[4-(pyridin-2-yl)phenyl]acetamide …
Displaying drugs 6326 - 6350 of 6831 in total