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Displaying drugs 1101 - 1125 of 6937 in total

Anileridine

Anileridine is a synthetic opioid and strong analgesic medication. It is a narcotic pain reliever used to treat moderate to severe pain. Narcotic analgesics act in the central nervous system (CNS) to relieve pain. Some of their side effects are also caused by actions in the CNS.
Approved
Illicit
Matched Synonyms: … 1-[2-(4-aminophenyl)ethyl]-4-phenyl-4-piperidinecarboxlic acid ethyl ester ... ethyl 1-(2-(4-aminophenyl)ethyl)-4-phenyl-4-piperidinecarboxylate ... ethyl 1-(4-aminophenethyl)-4-phenylisonipecotate …
Matched Iupac: … ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate …

Efavirenz

Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Synonyms: … (S)-6-chloro-4-(Cyclopropylethynyl)-1,4-dihydro-(S)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl ... (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one ... 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one …
Matched Iupac: … (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one …
Matched Mixtures name: … TOLAK ®3 TABLETAS RECUBIERTAS ... TOLAK ®3 TABLETAS RECUBIERTAS …
Matched Products: … SUSTIVA 600MG 3 MON PACK …

Parachlorophenol

P-chlorophenol is a white crystals with a strong phenol odor. Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible.
Approved
Matched Synonyms: … 4-chlorphenol ... 4-Chlorophenol …
Matched Iupac: … 4-chlorophenol …

Duloxetine

Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Synonyms: … (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine …
Matched Iupac: … methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine …

Ampicillin

Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Approved
Vet approved
Matched Synonyms: … D-(−)-6-(α-aminophenylacetamido)penicillanic acid …
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- …
Matched Salts cas: … 69-52-3 …
Matched Mixtures name: … ซัลแอม (3 กรัม ชนิดฉีด) ... Unasyn 3 g - Trockenstechampullen ... Unasyn 3 g - Trockensubstanz zur Infusionsbereitung …

Rilpivirine

Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance...
Approved
Matched Synonyms: … 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile …
Matched Iupac: … 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile …
Matched Salts cas: … 700361-47-3 …

Natalizumab

Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE …

Hexylresorcinol

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic. The compound may also be used commonly in various commercial cosmetic anti-aging...
Approved
Matched Synonyms: … 4-hexylresorcinol ... 4-hexyl-1,3-benzenediol …
Matched Iupac: … 4-hexylbenzene-1,3-diol …

Dequalinium

Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Synonyms: … Decamethylenebis(4-aminoquinaldinium chloride) ... 1,1'-Decamethylenebis(4-aminoquinaldinium chloride) ... 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride …
Matched Iupac: … 4-amino-1-[10-(4-amino-2-methylquinolin-1-ium-1-yl)decyl]-2-methylquinolin-1-ium …

Methyl nicotinate

Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Matched Synonyms: … 3-(Carbomethoxy)pyridine ... 3-(Methoxycarbonyl)pyridine ... Methyl 3-pyridinecarboxylate …
Matched Iupac: … methyl pyridine-3-carboxylate …

Delamanid

Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall . It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for...
Approved
Investigational
Matched Synonyms: … (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo ... (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo ... Imidazo(2,1-B)oxazole, 2,3-dihydro-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)-1-piperidinyl …
Matched Iupac: … 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy …

Cefdinir

Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to...
Approved
Matched Synonyms: … (6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0 ... (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino}-8-oxo-3-vinyl-5-thia-1-aza-bicyclo …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(N-hydroxyimino)acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo …

Quinestrol

The 3-cyclopentyl ether of ethinyl estradiol.
Approved
Matched Synonyms: … Estradiol-17-beta 3-cyclopentyl ether ... 17-alpha-Ethinylestradiol 3-cyclopentyl ether ... 17alpha-Ethynylestradiol 3-cyclopentyl ether …
Matched Description: … The 3-cyclopentyl ether of ethinyl estradiol. …

Diphenylpyraline

Diphenylpyraline is an antihistamine. Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites on effector cells. Antihistamines prevent, but do not reverse, responses mediated by histamine alone. Antihistamines antagonize, in varying degrees, most of the pharmacological effects of histamine, including urticaria and pruritus.
Approved
Investigational
Matched Synonyms: … 1-methyl-4-piperidyl benzhydryl ether ... 4-(benzhydryloxy)-1-methylpiperidine ... 4-(benzhydryloxy)-N-methylpiperidine …
Matched Iupac: … 4-(diphenylmethoxy)-1-methylpiperidine …
Matched Salts cas: … 132-18-3 …

Dacarbazine

An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
Approved
Investigational
Matched Synonyms: … 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide ... 4-(dimethyltriazeno)imidazole-5-carboxamide ... 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide …
Matched Iupac: … 5-[(1E)-3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide …

Tizanidine

Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an...
Approved
Investigational
Matched Synonyms: … 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole …
Matched Iupac: … 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine …
Matched Products: … TIZAN 4 ... โทโนไลท์ 4 ... ทีดาร์ 4 มก. …

Sufentanil

Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes. Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched Synonyms: … N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide ... N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide …
Matched Iupac: … N-[4-(methoxymethyl)-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropanamide …
Matched Salts cas: … 60561-17-3 …

Cinnamaldehyde

Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia. Sensitivity to cinnamaldehyde may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … (E)-3-Phenylpropenal ... (E)-3-Phenyl-propenal ... (3E)-3-phenylprop-2-enal …
Matched Iupac: … (2E)-3-phenylprop-2-enal …

Abiraterone

Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Synonyms: … (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol ... 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol …
Matched Iupac: … (3aS,3bR,7S,9aR,9bS,11aS)-9a,11a-dimethyl-1-(pyridin-3-yl)-3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H, …

Cefmenoxime

Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections. It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.
Approved
Matched Synonyms: … (6R,7R)-7-((Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-((1-methyl-1H-5-tetraazolylthio)methyl ... (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol …

Ambroxol

Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the...
Approved
Investigational
Matched Synonyms: … Cyclohexanol, 4-((2-amino-3,5-dibromobenzyl)amino)- (E)- ... trans-4-((2-Amino-3,5-dibromobencil)amino)ciclohexanol ... trans-4-((2-Amino-3,5-dibromobenzyl)amine)cyclohexanol …
Matched Iupac: … (1r,4r)-4-{[(2-amino-3,5-dibromophenyl)methyl]amino}cyclohexan-1-ol …
Matched Salts cas: … 23828-92-4 …
Matched Products: … AXOL LIQUID 3 mg/ml …

Polydatin

Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Synonyms: … trans-resveratrol 3-β-glucoside ... resveratrol-3-O-b-mono-D-glucoside ... trans-resveratrol 3-β-D-glucoside …
Matched Iupac: … (2S,3R,4S,5S,6R)-2-{3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenoxy}-6-(hydroxymethyl)oxane-3,4,5 …

Aminosalicylic acid

An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Synonyms: … 4-aminosalicylate ... 4-aminosalicylic acid ... 4-amino-2-hydroxybenzoic acid …
Matched Iupac: … 4-amino-2-hydroxybenzoic acid …
Matched Salts cas: … 133-15-3 …
Matched Categories: … 4-aminosalicylic acid …

Chloroxylenol

Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Synonyms: … 4-chloro-m-xylenol ... 3,5-dimethyl-4-chlorophenol ... 4-chloro-3,5-dimethylphenol …
Matched Iupac: … 4-chloro-3,5-dimethylphenol …
Matched Products: … Ultradex Liq 3% ... Suite Scrub Foam Liq 3% ... Suite Scrub 1000 Liq 3% …

Chloramphenicol

An antibiotic first isolated from cultures of Streptomyces venezuelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)...
Approved
Vet approved
Withdrawn
Matched Synonyms: … D-(−)-2,2-dichloro-N-(β-hydroxy-α-(hydroxymethyl)-p-nitrophenylethyl)acetamide …
Matched Iupac: … 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide …
Matched Mixtures name: … CORTIFENOL H POMADA OFTALMICA 4 G …
Displaying drugs 1101 - 1125 of 6937 in total