Displaying drugs 1126 - 1150 of 6937 in total
Nepafenac
Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Approved
Investigational
Matched Synonyms: … 2-amino-3-benzoylbenzeneacetamide …
Matched Iupac: … 2-(2-amino-3-benzoylphenyl)acetamide …
Matched Products: … NEVANAC 3 MG/ML GÖZ DAMLASI, SÜSPANSİYON …
Matched Iupac: … 2-(2-amino-3-benzoylphenyl)acetamide …
Matched Products: … NEVANAC 3 MG/ML GÖZ DAMLASI, SÜSPANSİYON …
Thiabendazole
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Approved
Vet approved
Matched Synonyms: … 4-(2-benzimidazolyl)thiazole ... 2-(thiazol-4-yl)benzimidazole ... 2-(4-thiazolyl)-1H-benzimidazole …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole …
Ataluren
Ataluren is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. More specifically, ataluren is used in the small group of patients whose...
Approved
Investigational
Matched Synonyms: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid …
Matched Iupac: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid …
Matched Iupac: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid …
Betazole
A histamine H2 agonist used clinically to test gastric secretory function.
Approved
Matched Synonyms: … 1H-pyrazole-3-ethanamine ... 3-(2-aminoethyl)pyrazole ... 2-(3-pyrazolyl)ethylamine …
Furosemide
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Synonyms: … 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid ... 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid ... 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid …
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid …
Matched Products: … Lasix 40 mg/4 ml Ampullen ... FUROSON 40 MG/4 ML IM/IV AMPUL, 5 ADET …
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid …
Matched Products: … Lasix 40 mg/4 ml Ampullen ... FUROSON 40 MG/4 ML IM/IV AMPUL, 5 ADET …
Emedastine
Emedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Approved
Matched Synonyms: … 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole ... 1-[2-(ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole ... 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole …
Matched Iupac: … 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole …
Matched Salts cas: … 87233-62-3 …
Matched Products: … แผ่นแปะอัลเลเซก้า 4 มิลลิกรัม …
Matched Iupac: … 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole …
Matched Salts cas: … 87233-62-3 …
Matched Products: … แผ่นแปะอัลเลเซก้า 4 มิลลิกรัม …
Zonisamide
Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Synonyms: … 1,2-Benzisoxazole-3-methanesulfonamide ... 3-(Sulfamoylmethyl)-1,2-benzisoxazole ... Benzo[d]isoxazol-3-yl-methanesulfonamide …
Matched Iupac: … (1,2-benzoxazol-3-yl)methanesulfonamide …
Matched Iupac: … (1,2-benzoxazol-3-yl)methanesulfonamide …
Prazosin
Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists.
Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress...
Approved
Matched Synonyms: … 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline ... 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine …
Matched Iupac: … 2-[4-(furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Salts cas: … 19237-84-4 …
Matched Iupac: … 2-[4-(furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Salts cas: … 19237-84-4 …
Edrophonium
A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Approved
Matched Synonyms: … (3-hydroxyphenyl)dimethylethylammonium ... 3-hydroxy-N,N-dimethyl-N-ethylanilinium ... N-ethyl-3-hydroxy-N,N-dimethylanilinium …
Matched Iupac: … N-ethyl-3-hydroxy-N,N-dimethylanilinium …
Matched Iupac: … N-ethyl-3-hydroxy-N,N-dimethylanilinium …
Eszopiclone
Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia. It is the active stereoisomer of zopiclone, belonging to the class of drugs known as cyclopyrrolones.[A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity , offering a safer alternative to other drugs used...
Approved
Investigational
Matched Synonyms: … (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine- ... (+)-(5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl-4-methylpiperazine- ... 1-Piperazinecarobxylic acid,4-methyl-,(5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4- …
Matched Iupac: … (5S)-6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate …
Matched Products: … ZOPLIMAX® 3 ... ISOKLON® 3 MG ... VALNOC®3 MG TABLETAS …
Matched Iupac: … (5S)-6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate …
Matched Products: … ZOPLIMAX® 3 ... ISOKLON® 3 MG ... VALNOC®3 MG TABLETAS …
Liraglutide
Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist.[Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid...
Approved
Matched Synonyms: … Arg34Lys26-(N-ε-(γ-Glu(N-α-hexadecanoyl)))-GLP-1[7-37] …
Matched Mixtures name: … XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 ADET …
Matched Products: … VICTOZA 6 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 ADET ... SAXENDA 6 MG/ML ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM, 3 ENJEKTÖR …
Matched Mixtures name: … XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 ADET …
Matched Products: … VICTOZA 6 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 ADET ... SAXENDA 6 MG/ML ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM, 3 ENJEKTÖR …
Tarlatamab
Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific ... Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens …
Matched Description: … bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 …
Matched Description: … bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 …
Erythromycin
Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections, including those...
Approved
Investigational
Vet approved
Matched Synonyms: … 3''-O-demethylerythromycin …
Matched Iupac: … (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy ... }-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13 …
Matched Mixtures name: … ACNEMIX % 5 + % 3 JEL, 46.6 GR ... BENZADERM %3+%5 TOPİKAL JEL, 46,6 GRAM …
Matched Products: … BONAC® GEL 4% ... ERYACNE GEL 4% ... ERITSA %4 JEL ,30 G …
Matched Iupac: … (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy ... }-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13 …
Matched Mixtures name: … ACNEMIX % 5 + % 3 JEL, 46.6 GR ... BENZADERM %3+%5 TOPİKAL JEL, 46,6 GRAM …
Matched Products: … BONAC® GEL 4% ... ERYACNE GEL 4% ... ERITSA %4 JEL ,30 G …
Stavudine
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Approved
Investigational
Matched Synonyms: … 2',3'-Didehydro-3'-deoxythimidine ... 3'-Deoxy-2'-thymidinene …
Norelgestromin
Norelgestromin is a drug used in contraception. Norelgestromin is the active progestin responsible for the progestational activity that occurs in women after application of ORTHO EVRA patch.
Approved
Investigational
Matched Synonyms: … Norplant 3-oxime ... D-Norgestrel 3-oxime ... Levonorgestrel 3-oxime …
Tetrabenazine
A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders. It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August 15, 2008.
Approved
Investigational
Matched Synonyms: … 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one ... 2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine ... 2-oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine …
Matched Iupac: … 9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one …
Matched Iupac: … 9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one …
Sulfadimethoxine
Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide ... 2,6-dimethoxy-4-sulfanilamidopyrimidine ... N(1)-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide …
Matched Iupac: … 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide …
Matched Iupac: … 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide …
Midostaurin
Midostaurin (as Rydapt) is a multitarget kinase inhibitor for the treatment for adult patients with newly diagnosed acute myeloid leukemia (AML) who have a specific genetic mutation called FLT3. It was initially characterized as a potential broad-spectrum antineoplastic agent, with activity toward diverse solid and hematopoietic tumors . It was...
Approved
Investigational
Matched Synonyms: … 4'-N-benzoylstaurosporine …
Matched Iupac: … N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{ ... 8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{ ... 8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Ospemifene
Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.
Approved
Investigational
Matched Synonyms: … 2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol ... 2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol …
Matched Iupac: … 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethan-1-ol …
Matched Iupac: … 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethan-1-ol …
Phenylbutazone
A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). Although phenylbutazone is effective in gouty arthritis, risk/benefit considerations indicate that this drug should not be employed for this...
Approved
Vet approved
Matched Synonyms: … 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine ... 4-butyl-1,2-diphenyl-pyrazolidine-3,5-dione ... 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione …
Matched Iupac: … 4-butyl-1,2-diphenylpyrazolidine-3,5-dione …
Matched Iupac: … 4-butyl-1,2-diphenylpyrazolidine-3,5-dione …
Edaravone
Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. It has three tautomers. Edaravone works to scavenge reactive oxygen species, which have been implicated in neurological disorders, such as amyotrophic lateral sclerosis (ALS) and cerebral ischemia.[A19140,L44007,A254257]
The intravenous formulation of edaravone was first approved in Japan in...
Approved
Investigational
Matched Synonyms: … 3-methyl-1-phenyl-5-pyrazolone ... 3-methyl-1-phenylpyrazol-5-one ... 1-phenyl-3-methyl-5-oxo-2-pyrazoline …
Matched Iupac: … 3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one …
Matched Iupac: … 3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one …
Vonoprazan
Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+-ATPase-mediated gastric acid secretion. PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations. Furthermore, vonoprazan is 350-times more potent...
Approved
Investigational
Matched Synonyms: … 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine …
Matched Iupac: … {[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl]methyl}(methyl)amine …
Matched Iupac: … {[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl]methyl}(methyl)amine …
Cefotetan
A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.
Approved
Matched Synonyms: … (6R,7S)-7-(4-(carbamoylcarboxymethylene)-1,3-dithiethane-2-carboxamido)-7-methoxy-3-(((1-methyl-1H-tetrazol …
Matched Iupac: … (6R,7S)-7-{4-[carbamoyl(carboxy)methylidene]-1,3-dithietane-2-amido}-7-methoxy-3-{[(1-methyl-1H-1,2,3,4 …
Matched Iupac: … (6R,7S)-7-{4-[carbamoyl(carboxy)methylidene]-1,3-dithietane-2-amido}-7-methoxy-3-{[(1-methyl-1H-1,2,3,4 …
Metoclopramide
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Synonyms: … 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide ... 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide ... 4-amino-5-chloro-2-methoxy-N-(β-diethylaminoethyl)benzamide …
Matched Iupac: … 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide …
Matched Products: … METOCLOPRAMIDA 4 MG/ML GOTAS ... METOCLOPRAMIDA 4 MG / ML GOTAS …
Matched Iupac: … 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide …
Matched Products: … METOCLOPRAMIDA 4 MG/ML GOTAS ... METOCLOPRAMIDA 4 MG / ML GOTAS …
Medrysone
Medrysone is a corticosteroid used in ophthalmology.
Approved
Matched Synonyms: … 11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione …
Displaying drugs 1126 - 1150 of 6937 in total