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Displaying drugs 226 - 250 of 705 in total

Octinoxate

Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase...
Approved
Investigational
Matched Description: … Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize ... Its use in pharmaceutical and cosmetic formulations is approved by FDA. ... nanoparticles or other water-resistant liposomes in formulations to increase the localization at the epidermis and …
Matched Mixtures name: … Uv Lock Flower Kids and Junior Sun Spf35 Pa Plus Plus ... CRème Montagne Et Grand Froid ... Creme Bronzante Neige Et Montagne …
Matched Categories: … Emollients and Protectives …
Matched Products: … Soleil D'uv - Liq Top 3% ... Huile Soleil - Liq Top 4% ... Huile Solaire - Liq Top 2% …

Cibisatamab

Investigational
Matched Synonyms: … (cea) and cd3 epsilon chain (cd3e) on t-cells ... Anti-cea/cd3 bispecific antibody ro6958688 ... Humanized immunoglobulin g1 (igg1) t-cell bispecific (tcb) antibody targeting carcinoembryonic antigen …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Lym-1-I-131

Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.
Investigational
Matched Synonyms: … Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma ... Monoclonal antibody LYM-1-I-131 ... Iodine I 131 Lym-1 Monoclonal Antibody …
Matched Description: … Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant …

Purslane

Purslane is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Portulaca Oleracea Flowering Top ... Portulaca Oleracea Flower/leaf/stem Extract ... Portulaca Neglecta Top …

TRK-001

TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Matched Synonyms: … Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and …

Cetrorelix

Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not...
Approved
Investigational
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Cetrotide 0.25 mg powder and solvent for solution for injection …

Aluminum zirconium tetrachlorohydrex gly

Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … Ap 22% (regular,sport,musk and Unscented) ... Mitchum Clear Gel A.P. and Deod.supersport ... Body Satin Antiperspirant and Deodorant …

STRO-001

Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable ... Anti-CD74 antibody-drug conjugate STRO-001 ... STRO-001, a site-specific anti-CD74 antibody-drug conjugate …

Delolimogene mupadenorepvec

Investigational
Matched Synonyms: … Dna (synthetic human adenovirus 5/35 vector load703 human cd137 ligand and trimerized membrane-bound …

Cotsiranib

Investigational
Matched Synonyms: … interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and …

PEP0101

PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …

Tarlatamab

Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens ... cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific …

Hiltonol

Investigational
Matched Synonyms: … homopolymer, complex with 5'-inosinic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and ... homopolymer, complex with 5'-cytidylic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and ... L-lysine, homopolymer, compd. with cellulose carboxymethyl ether and 5'-inosinic acid homopolymer complex …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …

Triptorelin

Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Description: … and testicular and ovarian steroidogenesis. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial …

Witch hazel

Nutraceutical
Matched Mixtures name: … frida mom Labor and Delivery Plus Postpartum Recovery ... frida mom Labor and Delivery Plus Postpartum Recovery ... Tucks Multi-Care Relief Kit (Tucks Hemorrhoidal and Tucks Medicated Cooling 40 Count) …
Matched Categories: … Astringents and Deodorants ... Herbs and Natural Products ... Skin and Mucous Membrane Agents …
Matched Products: … Up and Up Medicated Hemorrhoidal Pads ... Tone and Line Change Pack ... Hamsoa Atoby Medi Bath And …

Taniraleucel

Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, …

Povidone-iodine

Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Description: … Shelanski and M. V. Shelanski. ... Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine ... Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic …
Matched Mixtures name: … Physician EZ Use Joint Tunnel and Trigger Kit ... JTT Physicians Joint, Tunnel and Trigger ... BRAUNODERM (IN 250ML AND 1000ML PLASTIC) …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Bella Flore ... Fresh and Pure ... 3M Skin and Nasal Antiseptic …

DCLL-9718S

DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer ... THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal …
Matched Description: … DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Carboxymethylcellulose

Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or thickener and emulsifier. It is also one of the most common viscous polymers used in...
Approved
Investigational
Matched Description: … It is added in food products as a viscosity modifier or thickener and emulsifier. ... is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and ... in the treatment of aqueous tear-deficient dry eye symptoms and ocular surface staining [A33029]. …
Matched Mixtures name: … Equate Day and Night Restore Tears ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) …
Matched Categories: … Anorexigenic Agents & Respiratory and CNS Stimulants …
Matched Products: … Up and Up Lubricant ... Up and Up Lubricant Refreshing ... Up and Up Lubricant Refreshing Tears …

Lanolin

Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Description: … It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and …
Matched Mixtures name: … PETROLATUM and LANOLIN ... A and D Diaper Rash and Skin Protectant ... Vitamins A and D Diaper Rash …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …

Suratadenoturev

Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … telomerase reverse transcriptase (hTERT) and IRES, respectively. ... -5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and ... A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human …

Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen

Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. …

Apadamtase alfa

Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and ... thrombospondin type 1 motif, member 13), which is responsible for cleaving large von Willebrand factor multimers and …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... apadamtase alfa and cinaxadamtase alfa …

AB-201

AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … allogeneic cord blood-derived NK cells that have been genetically modified to express a HER2-directed CAR and …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …

OTL-102

OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
Displaying drugs 226 - 250 of 705 in total