Displaying drugs 2651 - 2675 of 3380 in total
ONL-1204
Investigational
Matched Synonyms: … His-his-ile-tyr-leu-gly-ala-val-asn-tyr-ile-tyr-nh2 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Idasanutlin
Idasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia.
Investigational
Matched Synonyms: … BENZOIC ACID, 4-((((2R,3S,4R,5S)-3-(3-CHLORO-2-FLUOROPHENYL)-4-(4-CHLORO-2-FLUOROPHENYL)-4-CYANO-5-(2,2 …
Matched Iupac: … fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-amido]-3-methoxybenzoic acid …
Matched Description: … treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Proto-Oncogene Proteins c-mdm2, antagonists & inhibitors …
Matched Iupac: … fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-amido]-3-methoxybenzoic acid …
Matched Description: … treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Proto-Oncogene Proteins c-mdm2, antagonists & inhibitors …
1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE)
Experimental
Matched Name: … 1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL …
4-Hydroxy-L-Threonine-5-Monophosphate
Experimental
Matched Name: … 4-Hydroxy-L-Threonine-5-Monophosphate …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-4-(phosphonooxy)butanoic acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-4-(phosphonooxy)butanoic acid …
6-diazo-5-oxo-L-norleucine
6-diazo-5-oxo-L-norleucine is a broad-acting glutamine antagonist.
Investigational
Matched Name: … 6-diazo-5-oxo-L-norleucine …
Matched Iupac: … (2S)-2-amino-6-diazo-5-oxohexanoic acid …
Matched Description: … 6-diazo-5-oxo-L-norleucine is a broad-acting glutamine antagonist. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … (2S)-2-amino-6-diazo-5-oxohexanoic acid …
Matched Description: … 6-diazo-5-oxo-L-norleucine is a broad-acting glutamine antagonist. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
N-(3-Carboxypropanoyl)-L-phenylalanyl-3-carboxy-O-(carboxymethyl)-N-pentyl-L-tyrosinamide
Experimental
Matched Name: … N-(3-Carboxypropanoyl)-L-phenylalanyl-3-carboxy-O-(carboxymethyl)-N-pentyl-L-tyrosinamide …
Matched Iupac: … carboxymethoxy)-5-[(2S)-2-[(2S)-2-(3-carboxypropanamido)-3-phenylpropanamido]-2-(pentylcarbamoyl)ethyl]benzoic acid …
Matched Iupac: … carboxymethoxy)-5-[(2S)-2-[(2S)-2-(3-carboxypropanamido)-3-phenylpropanamido]-2-(pentylcarbamoyl)ethyl]benzoic acid …
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE
Experimental
Matched Name: … N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE …
Matched Iupac: … (2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-methylpentanamido]-3-methylpentanoic acid …
Matched Iupac: … (2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-methylpentanamido]-3-methylpentanoic acid …
CTS-1027
CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection.
Experimental
Investigational
Matched Synonyms: … 4-(4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL )-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE ... 4-(4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL)-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE …
Matched Description: … CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Description: … CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen
Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup W-135. The vaccine contains N. meningitis serogroup W-135 capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Synonyms: … Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine …
Matched Description: … vaccine contains *N. meningitis* serogroup W-135 capsular polysaccharide antigens that are purified and ... individually conjugated to diphtheria toxoid protein that are extracted from *Corynebacterium diphtheriae …
Matched Description: … vaccine contains *N. meningitis* serogroup W-135 capsular polysaccharide antigens that are purified and ... individually conjugated to diphtheria toxoid protein that are extracted from *Corynebacterium diphtheriae …
Anti-CD7 CAR T-cell therapy
Investigational
Matched Synonyms: … A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7 …
Astemizole
Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
Approved
Withdrawn
Matched Description: … was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high …
Matched Products: … ASTEMIZOL HIGEA TABLETAS …
Matched Products: … ASTEMIZOL HIGEA TABLETAS …
A-dmDT390-bisFv(UCHT1)
A-dmDT390-bisFv(UCHT1) is under investigation in clinical trial NCT02943642 (Safety and Effectiveness of A-dmdt390-bisfv(ucht1) Fusion Protein in Subjects With Mycosis Fungoides).
Investigational
Matched Synonyms: … Recombinant anti-cdr-bi-single-chain-fv-diphtheria toxin fusion protein ... Recombinant anti-cdr-bi-single-chain-fv-diptheria toxin fusion protein …
Matched Description: … A-dmDT390-bisFv(UCHT1) is under investigation in clinical trial NCT02943642 (Safety and Effectiveness ... of A-dmdt390-bisfv(ucht1) Fusion Protein in Subjects With Mycosis Fungoides). …
Matched Description: … A-dmDT390-bisFv(UCHT1) is under investigation in clinical trial NCT02943642 (Safety and Effectiveness ... of A-dmdt390-bisfv(ucht1) Fusion Protein in Subjects With Mycosis Fungoides). …
Dinor-N(Omega)-Hydroxy-L-Arginine
Experimental
Matched Name: … Dinor-N(Omega)-Hydroxy-L-Arginine …
Matched Iupac: … (2S)-2-amino-3-[(E)-[amino(hydroxyamino)methylidene]amino]propanoic acid …
Matched Iupac: … (2S)-2-amino-3-[(E)-[amino(hydroxyamino)methylidene]amino]propanoic acid …
L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal
C-101, also called Myodur, is developed for the treatment of Duchenne’s muscular dystrophy (DMD) which is a morbid genetic disease that can lead to death in late adolescence due to accelerated skeletal muscle breakdown. C-101 includes a carnitine carrier molecule and a leupeptin analogue, a known calpain inhibitor. Calpain is...
Investigational
Matched Name: … L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal …
Matched Description: … C-101 includes a carnitine carrier molecule and a leupeptin analogue, a known calpain inhibitor. ... Calpain is the primary protease that degrades skeletal muscle. …
Matched Description: … C-101 includes a carnitine carrier molecule and a leupeptin analogue, a known calpain inhibitor. ... Calpain is the primary protease that degrades skeletal muscle. …
HONH-BENZYLMALONYL-L-ALANYLGLYCINE-P-NITROANILIDE
Experimental
Matched Name: … HONH-BENZYLMALONYL-L-ALANYLGLYCINE-P-NITROANILIDE …
Cladribine
An antineoplastic agent used in the treatment of lymphoproliferative diseases including hairy-cell leukemia. Cladribine is also used to treat relapsing forms of multiple sclerosis.
Approved
Investigational
Matched Synonyms: … 2-Chloro-2'-deoxy-beta-adenosine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents …
Apraglutide
Investigational
Matched Synonyms: … His-gly-asp-gly-ser-phe-ser-asp-glu-nle-d-phe-thr-ile-leu-asp-leu-leu-ala-ala-arg-asp-phe-ile-asn-trp-leu-ile-gln-thr-lys-ile-thr-asp-nh2 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Glatiramer
Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a...
Approved
Investigational
Matched Synonyms: … (T,G)-A-L …
Matched Description: … Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine ... , and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. ... [A248880] It was approved by the FDA in 1996, and a generic version became available in 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins …
Matched Description: … Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine ... , and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. ... [A248880] It was approved by the FDA in 1996, and a generic version became available in 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins …
(2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone
Experimental
Matched Synonyms: … N2-Acetyl-N-[(2S)-5-chloro-3-oxo-1-phenyl-2-pentanyl]-L-alaninamide …
Matched Name: … (2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone …
Matched Name: … (2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone …
Racemetyrosine
Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer).
Investigational
Matched Synonyms: … D,L-metyrosine …
Matched Iupac: … 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
RGX-111
RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. Developed by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).
Investigational
Matched Synonyms: … Adeno-associated virus vector serotype 9 expressing human a-L-iduronidase …
Matched Description: … RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. …
Matched Description: … RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. …
Sorbitol
A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
Approved
Matched Synonyms: … L-Gulitol …
Matched Description: … It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for ... Sorbitol occurs naturally and is also produced synthetically from glucose. ... A polyhydric alcohol with about half the sweetness of sucrose. …
Matched Mixtures name: … INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) ... Char-flo With Sorbitol - Sus …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Diet, Food, and Nutrition ... Indicators and Reagents …
Matched Description: … It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for ... Sorbitol occurs naturally and is also produced synthetically from glucose. ... A polyhydric alcohol with about half the sweetness of sucrose. …
Matched Mixtures name: … INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) ... Char-flo With Sorbitol - Sus …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Diet, Food, and Nutrition ... Indicators and Reagents …
MP-0250
Investigational
Matched Synonyms: … Designed ankyrin repeat protein (MP0250) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Recombinant Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Recombinant Proteins …
Displaying drugs 2651 - 2675 of 3380 in total