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Displaying drugs 401 - 425 of 631 in total
Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies...
Approved
Investigational
Matched Description: … Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally ... [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective ... at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along …
Matched Mixtures name: … Lansoprazole, Amoxicillin, and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin …
Matched Categories: … Alimentary Tract and Metabolism ... lansoprazole, amoxicillin and levofloxacin ... lansoprazole, clarithromycin and tinidazole ... lansoprazole, amoxicillin and metronidazole ... lansoprazole, tetracycline and metronidazole …
Matched Products: … Up and Up Lansoprazole ... Berkley and Jensen Lansoprazole ... Foster and Thrive Acid Reducer …
Dexmethylphenidate is the dextrorotary form of methylphenidate introduced in 2002 . It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant . It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181]. The d-isomer is thought to have greater effect with fewer side effects than the l-isomer or...
Approved
Investigational
Matched Description: … It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant[A177193]. …
Matched Salts name: … Dexmethylphenidate hydrochloride
Matched Categories: … Methylphenidate and isomer ... dexmethylphenidate and serdexmethylphenidate ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … Dexmethylphenidate Hydrochloride ... Dexmethylphenidate hydrochloride ... Dexmethylphenidate Hydrochloride Extended-Release …
Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes. Developed by Sangamo...
Experimental
Matched Synonyms: … IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM HIDS AND
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system …
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Matched Mixtures name: … Dobutamine Hydrochloride in Dextrose …
Matched Salts name: … Dobutamine hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … Dobutamine Hydrochloride ... DOBUTAMINE HYDROCHLORIDE ... Dobutamine Hydrochloride in Dextrose …
Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
Approved
Vet approved
Matched Description: … It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt. …
Matched Mixtures name: … Fluorescein Sodium and Proparacaine Hydrochloride
Matched Salts name: … Proparacaine hydrochloride
Matched Products: … Proparacaine Hydrochloride ... PMS-proparacaine Hydrochloride Oph Soltn 0.5% …
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor...
Approved
Vet approved
Matched Description: … it produced minor hallucinogenic effects and shorter psychotomimetic effects. ... It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, ... It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients …
Matched Salts name: … Ketamine hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Ketamine Hydrochloride ... KETAMINE HYDROCHLORIDE ... Ketamine Hydrochloride Injection USP …
Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, spermidine and spermine. TETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925. Initially approved by the FDA in 1985...
Approved
Investigational
Matched Description: … It is a structural analog of linear polyamine compounds, [spermidine] and [spermine]. ... Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective ... TETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925 …
Matched Salts name: … Trientine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Products: … Trientine Hydrochloride ... Trientine hydrochloride
In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and ... Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Salts name: … Donepezil hydrochloride ... Donepezil hydrochloride monohydrate …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … ANDEM 5 MG FILM TABLET, 14 ADET ... ANDEM 5 MG FILM TABLET, 28 ADET ... ANDEM 10 MG FILM TABLET, 14 ADET …
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Mixtures name: … Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride
Matched Salts name: … Metformin hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... metformin and acarbose ... metformin and gemigliptin ... metformin and evogliptin ... metformin and linagliptin …
Matched Products: … Metformin Hydrochloride ... Metformin hydrochloride ... Metfomin Hydrochloride
Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder and irritable bowel syndrome.[A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small...
Approved
Matched Description: … and irritable bowel syndrome. ... Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor ... of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder …
Matched Salts name: … Dicyclomine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Dicyclomine Hydrochloride ... Dicyclomine hydrochloride ... Dicyclomine Hydrochloride USP …
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND
Matched Description: … as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Investigational
Matched Synonyms: … or 17,18)-dihydro-21h,23h-porphine-5,10-diyl)bisbenzenesulfonic acid, mixture of three isomers a, b and
RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
Investigational
Matched Synonyms: … Autologous CD34+-enriched Hematopoietic Stem and Progenitor Cells Transduced with Lentiviral Vector Carrying …
Investigational
Matched Synonyms: … CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK …
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Description: … a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ... [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone …
Matched Products: … Ceftazidime and Dextrose ... CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL …
Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) Internationally, diamorphine is controlled under...
Approved
Illicit
Investigational
Matched Description: … As heroin, it is illegal to manufacture, possess, or sell in the United States and the UK. ... (Merck Index, 11th ed) Internationally, diamorphine is controlled under Schedules I and IV of the Single …
Matched Salts name: … Diamorphine hydrochloride
Matched Products: … Diacetylmorphine Hydrochloride ... Diamorphine Hydrochloride Inj 30mg/ml BP ... Diamorphine Hydrochloride Inj 100mg/ml BP …
Experimental
Matched Synonyms: … Nestorone alcohol
Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Description: … Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and
Matched Mixtures name: … Lidocaine and Tetracaine ... Lidocaine and Tetracaine …
Matched Salts name: … Tetracaine hydrochloride
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Tetracaine Hydrochloride ... 0.5% TETRACAINE HYDROCHLORIDE ... Minims Tetracaine Hydrochloride
A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Approved
Matched Salts name: … Cyclopentolate hydrochloride
Matched Categories: … Mydriatics and Cycloplegics …
Matched Products: … Cyclopentolate Hydrochloride ... Minims Cyclopentolate Hydrochloride ... MINIMS CYCLOPENTOLATE HYDROCHLORIDE EYE DROPS 1% w/v …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders. Pramocaine is available by itself and in combination with other medications...
Approved
Matched Description: … Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. ... It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect ... bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders …
Matched Mixtures name: … Mineral Oil, Pramoxine Hydrochloride and Zinc Oxide ... Hydrocortisone Acetate and Pramoxine Hydrochloride ... Hydrocortisone Acetate and Pramoxine Hydrochloride
Matched Salts name: … Pramoxine hydrochloride
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Pramoxine Hydrochloride ... Pramoxine hydrochloride ... Anti Itch Soothing 1 Pramoxine Hydrochloride
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and
Matched Categories: … Amino Acids, Peptides, and Proteins …
An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Approved
Matched Description: … It has been used to treat hypertension and as a peripheral vasodilator. …
Matched Salts name: … Phenoxybenzamine hydrochloride
Matched Products: … Phenoxybenzamine Hydrochloride ... Phenoxybenzamine hydrochloride
A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
Approved
Withdrawn
Matched Description: … It is used in the treatment of peripheral vascular disease and in premature labor. ... A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. …
Matched Salts name: … Isoxsuprine hydrochloride
Matched Categories: … Alcohols ... Amino Alcohols
Matched Products: … Isoxsuprine Hydrochloride ... ISOXSUPRINE HYDROCHLORIDE
Displaying drugs 401 - 425 of 631 in total