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Displaying drugs 26 - 50 of 14472 in total
Liotrix is a synthetically derived thyroid hormone replacement preparation. It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. Liotrix was developed when it was believed that serum levels of both T4 and T3 were maintained by direct thyroidal secretion....
Approved
Matched Synonyms: … Levothyroxine Sodium mixture with Liothyronine Sodium
Matched Description: … It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in ... and combination hormone replacement therapy generally offers no therapeutic advantage. ... It is now known that the thyroid gland secretes approximately ten times more T4 than T3 and that 80% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. Tinzaparin is composed of molecules with and without a special site for high affinity binding...
Approved
Matched Synonyms: … Tinzaparin sodium
Matched Description: … It is an anticoagulant and considered an antithrombotic. ... It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. ... Tinzaparin is composed of molecules with and without a special site for high affinity binding to antithrombin …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Pegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability. Pegaptanib was granted FDA approval on 17 September 2004.
Approved
Investigational
Matched Synonyms: … Pegaptanib sodium
Matched Description: … neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Approved
Experimental
Matched Synonyms: … Ferric glyceryl phosphate
Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent. It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of leishmaniasis, a neglected tropical disease. It can be administered topically or orally and...
Approved
Investigational
Matched Synonyms: … hexadecyl 2-(trimethylazaniumyl)ethyl phosphate
Matched Iupac: … hexadecyl 2-(trimethylazaniumyl)ethyl phosphate
Matched Description: … It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of ... It can be administered topically or orally and is only indicated in patients aged 12 years or older. ... first line treatment for free-living amebae (FLA) infections such as primary amebic meningoencephalitis and
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... mannose-6-phosphate receptor (CI-MPR) in skeletal muscle, one of the main affected tissues in Pompe ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Anhydrous citric acid ... Citric acid,anhydrous ... Citric acid, anhydrous
Matched Mixtures name: … Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid …
Matched Categories: … Alimentary Tract and Metabolism …
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Synonyms: … Anhydrous tacrolimus ... Tacrolimus anhydrous ... Tacrolimus, anhydrous
Matched Description: … drug whose main use is after organ transplant to reduce the activity of the patient's immune system and ... the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and ... This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% …
Matched Categories: … Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Loracarbef is a carbacephem antibiotic sometimes grouped together with the second-generation cephalosporin antibiotics. It is marketed under the trade name Lorabid.
Approved
Investigational
Withdrawn
Matched Synonyms: … Anhydrous loracarbef ... Loracarbef anhydrous ... Loracarbef, anhydrous
Approved
Matched Name: … Sodium phosphate, monobasic, unspecified form …
Matched Mixtures name: … TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL Red Cell Preservative ... Phosphate
Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat...
Approved
Investigational
Vet approved
Matched Synonyms: … Potassium citrate anhydrous
Matched Description: … In the monohydrate form it is highly hygroscopic and deliquescent. …
Matched Mixtures name: … Potassium Citrate, Sodium Citrate, and Citric Acid ... Potassium Citrate-Sodium Citrate-Citric Acid ... Potassium Citrate-Sodium Citrate-Citric Acid …
Matched Categories: … Alimentary Tract and Metabolism …
Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Synonyms: … Hydroxocobalamin anhydrous ... Hydroxocobalaminum anhydrous
Matched Description: … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. ... Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B …
Matched Categories: … Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid …
Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of...
Approved
Matched Synonyms: … Enalaprilat anhydrous
Matched Description: … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule ... of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume ... to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Synonyms: … Argatroban anhydrous
Matched Description: … Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be ... Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and ... bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Synonyms: … Regadenoson anhydrous
Matched Description: … Manufactured by Astellas and FDA approved April 10, 2008. ... Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial …
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Synonyms: … Relebactam anhydrous
Matched Description: … [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... ] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal ... [label] It is considered to be a last-line treatment option and gained FDA approval as part of the combination …
Matched Salts name: … Relebactam sodium
Matched Categories: … imipenem, cilastatin and relebactam …
Approved
Matched Synonyms: … Anhydrous lithium citrate ... Lithium citrate (anhydrous) …
Lanthanum carbonate is a phosphate binder commonly used in clinical practice. It is marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is the largest of all pills filled in community pharmacies. Sometimes patients forget that Fosrenol is not swallowed whole, but instead should be chewed. This has led...
Approved
Matched Synonyms: … Lanthanum carbonate anhydrous
Matched Description: … Lanthanum should be taken with meals and binds to phosphate in the diet, preventing phosphate absorption ... Lanthanum carbonate is a phosphate binder commonly used in clinical practice. ... It is prescribed for treating high phosphate levels, mainly found in patients with chronic kidney disease …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Phosphate Binder ... Phosphate-removing Agents …
Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Synonyms: … Cilazapril anhydrous
Matched Description: … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries ... Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Matched Categories: … ACE Inhibitors and Diuretics ... cilazapril and diuretics …
Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. Dacomitinib was developed by Pfizer Inc and approved by the FDA on...
Approved
Investigational
Matched Synonyms: … Dacomitinib anhydrous
Matched Description: … [A40009] Dacomitinib was developed by Pfizer Inc and approved by the FDA on September 27, 2018. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Approved
Experimental
Matched Synonyms: … Manganese citrate anhydrous
Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.
Approved
Investigational
Matched Synonyms: … Flunisolide anhydrous
Matched Description: … It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves …
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Synonyms: … Ceftazidime anhydrous
Matched Description: … a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ... [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone …
Matched Salts name: … Ceftazidime sodium
Matched Products: … Ceftazidime and Dextrose ... CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL …
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Synonyms: … Anhydrous caffeine …
Matched Description: … [A187694] Caffeine is beneficial in preventing and treating apnea and bronchopulmonary dysplasia in newborns ... Caffeine is similar in chemical structure to [Theophylline] and [Theobromine]. ... variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and
Matched Mixtures name: … Butalbital, Aspirin, Caffeine and Codeine Phosphate ... Butalbital, Aspirin, Caffeine and Codeine Phosphate ... Butalbital, Aspirin, Caffeine and Codeine Phosphate
Matched Categories: … caffeine and sodium benzoate ... Respiratory and CNS Stimulants ... Caffeine and Caffeine Containing Products ... Anorexigenic Agents & Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … Caffeine and Sodium Benzoate …
Penicillium glaucum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, penicillium glaucum ... Molds, rusts and smuts, penicillium glaucus …
Displaying drugs 26 - 50 of 14472 in total