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Displaying drugs 501 - 525 of 771 in total

Ranibizumab

Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … , and Health Canada respectively. ... [L41429] It is marketed under the brand names LUCENTIS and SUSVIMO. ... after [bevacizumab], another anti-VEGF anticancer drug, was discovered to inhibit neovascularization and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... LUCENTIS SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 1.65mg/0.165ml …

Gentian violet cation

A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Approved
Matched Description: … A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Gentiane Violet Liq Top …

Nonoxynol-9

Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams,...
Approved
Withdrawn
Matched Description: … It is the most commonly used spermicidal contraceptive in the UK and the USA. ... When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without ... N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and …
Matched Products: … Vcf Contraceptive Pre-filled Applicators …

Calcipotriol

Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Approved
Matched Mixtures name: … Calcipotriene and Betamethasone Dipropionate ... Calcipotriene and Betamethasone Dipropionate ... Calcipotriene and Betamethasone Dipropionate …
Matched Categories: … Vitamin D and Analogues ... Skin and Mucous Membrane Agents …
Matched Products: … Dovonex Solution - Top 50mcg/ml …

Inclisiran

Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density lipoprotein cholesterol (LDL-C) levels. By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma...
Approved
Investigational
Matched Description: … RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and ... plasma LDL-C levels offers an additional benefit of reducing the risk of cardiovascular disease (CVD) and ... 11, 2020, the European Commission (EC) granted authorization for marketing inclisiran as the first and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Sybrava 284mg/1.5ml Solution for Injection in Pre-filled Syringe …

Aracytidine 5'-monophosphate

Experimental
Matched Synonyms: … Aracytidine 5'-phosphate ... Cytosine arabinose-5'-phosphate ... 1-beta-D-Arabinofuranosylcytosine 5'-phosphate …

Muparfostat

Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived from the extracellular phosphomannan of the yeast Pichia (Hansenula) holstii, with potential antiangiogenic activity.
Investigational
Matched Synonyms: … Mannopentaose phosphate sulfate ... Sulfated mannopentaose phosphate ... -D-MANNAN, (1->3)-, 6-(DIHYDROGEN PHOSPHATE) TRIS(HYDROGEN SULFATE) …

Ribose-5-phosphate

Experimental
Matched Synonyms: … D-Ribose 5-phosphate ... aldehydo-D-ribose 5-phosphate …
Matched Name: … Ribose-5-phosphate …
Matched Categories: … Sugar Phosphates …

2'-cytidylic acid

Experimental
Matched Synonyms: … Cytidine 2'-phosphate ... Cytidine, 2'-phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Lixisenatide

Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide …
Matched Products: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG (50mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MCG (100mcg/mL) …

Ubidecarenone

Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is...
Approved
Investigational
Nutraceutical
Matched Description: … From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number ... [A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative ... [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant …
Matched Mixtures name: … Vitamin E and Coq10 ... Co-q10 and Vitamin E ... Co-q10 M.R.B. 100mg and Vitamin E …
Matched Categories: … Diet, Food, and Nutrition ... Enzymes and Coenzymes …
Matched Products: … Coenzyme Q10 With Hawthorn Extract and Citrus Bioflavonoids …

Golimumab

Golimumab is a human IgG1қ monoclonal antibody derived from immunizing genetically engineered mice with human TNFα. Golimumab binds and inhibits soluble and transmembrane human TNFα. Increased TNFα is associated with chronic inflammation. Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with...
Approved
Matched Description: … Golimumab binds and inhibits soluble and transmembrane human TNFα. ... Additionally in children and adolescents taking golimumab, there have been lymphoma and other malignancies ... In the U.S. and Canada, golimumab is marketed under the brand name Simponi®. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Solution for Injection in Pre-filled Syringe 100 mg/1.0 ml ... Simponi Solution for Injection in Pre-filled Syringe 50 mg/0.5 ml ... SIMPONI SOLUTION FOR INJECTION IN PRE-FILLED PEN 45MG/0.45ML …

Isoflurophate

An irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically. (From Martindale, The Extra Pharmacopoeia, 29th ed, p1330)
Approved
Investigational
Withdrawn
Matched Synonyms: … Fluorodiisopropyl phosphate ... O,O'-diisopropyl phosphoryl fluoride …
Matched Description: … Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically …

Bazlitoran

Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Semaglutide

Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.[A31421,L8681] Other members of this drug class include Exenatide and Liraglutide. Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection...
Approved
Investigational
Matched Description: … and reducing blood glucose. ... [A31421,L8681] Other members of this drug class include [Exenatide] and [Liraglutide]. ... 1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … OZEMPIC 1MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML ... OZEMPIC 0.25MG, 0.5MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML ... Ozempic® 1.34 mg/ml (1 mg/dose) Solution for injection in pre-filled pen …

Estramustine phosphate

A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Approved
Investigational
Matched Synonyms: … Estramustine 17-(dihydrogen phosphate) …
Matched Name: … Estramustine phosphate …
Matched Description: … A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also …

Ribavirin monophosphate

Experimental
Matched Synonyms: … Virazole 5'-phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Ferric glycerophosphate

Approved
Experimental
Matched Synonyms: … Ferric glyceryl phosphate …

D-glyceraldehyde 3-phosphate

An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
Experimental
Matched Synonyms: … Glyceraldehyde-3-phosphate ... D-Glyceraldehyde 3-phosphate …
Matched Name: … D-glyceraldehyde 3-phosphate …
Matched Description: … An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis. …

Riboflavin

Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. ... Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. ... It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms …
Matched Mixtures name: … Isotonix Advanced B-complex Vitamins With Potassium and Magnesium ... Chela Potassium Plus ... Potassium Plus Vit B Complex …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Products: … Riboflavin 5 Phosphate Cap 50mg …

Hydrocortamate

Hydrocortamate is a synthetic glucocorticoid used for its anti-inflammatory or immunosuppressive properties to treat inflammation due to corticosteroid-responsive dermatoses. Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger a variety of important cardiovascular, metabolic, immunologic and homeostatic effects.
Approved
Matched International brands: … Ulcort top …
Matched Description: … trigger a variety of important cardiovascular, metabolic, immunologic and homeostatic effects. ... Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and …

Lipegfilgrastim

Lipegfilgrastim, previously known as XM22, is a pegylated, recombinant granulocyte colony-stimulating factor (G-CSF) that was synthetized using a highly site-specific glycoPEGylation technology . It is used as an alternate to DB00019 for prophylactic use in cancer patients receiving chemotherapy and at risk for developing chemotherapy-induced neutropenia. Since July 2013, lipegfilgrastim...
Approved
Investigational
Matched Description: … Neutropenia and febrile neutropenia (FN) are frequent and potentially fatal complications that occur ... life-threatening infection and sepsis. ... It aims to reduce the duration of neutropenia and the incidence of febrile neutropenia. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … LONQUEX SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 6MG/0.6ML …

TMP

Experimental
Matched Synonyms: … 5-methyluridine 5'-phosphate ... ribothymidine 5'-phosphate ... ribosylthymine 5'-phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Hepatitis B immune globulin

Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. According to the Centers for Disease Control...
Approved
Investigational
Matched Description: … The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. ... According to the Centers for Disease Control and Prevention (CDC), the hepatitis B vaccine was the first ... During the process, viruses are deactivated, and in the final steps, solvents used in the preparation …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … HyperHEP B S/D Pre-filled Syringe 1mL ... HyperHEP B S/D Pre-filled Syringe 0.5mL ... Niuliva Solution For Infusion In Pre-Filled Syringe 600 I.U./2.4 ml …

Tocilizumab

Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Tocilizumab was granted FDA approval on 8 January 2010 to treat a...
Approved
Matched Description: … [L40164] Subsequently, it was granted approval by Health Canada and the FDA in October [L43697] and December ... Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and ... autoimmune disorders, such as different types of arthritis and cytokine release syndrome. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ACTEMRA (162 MG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE) ... ACTEMRA 162MG/0.9ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... Actemra 162mg Solution for Injection in Pre-filled Syringe 162mg/0.9ml …
Displaying drugs 501 - 525 of 771 in total