Did you mean anhydrous cupric acid and sodium citrate?
Displaying drugs 576 - 600 of 654 in total
Pilsicainide
Pilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.
Investigational
Matched Categories: … Sodium Channel Blockers …
Glisoxepide
Glisoxepide is one of the sulphonamide-derived oral antidiabetic drugs. It inhibits the uptake of bile acids into isolated rat hepatocytes. However it inhibits taurocholate uptake only in the absence of sodium ions. Glisoxepide uptake could be further inhibited by blockers of the hepatocellular monocarboxylate transporter, by the loop diuretic bumetanide,...
Investigational
Matched Description: … However it inhibits taurocholate uptake only in the absence of sodium ions. ... transporter, by the loop diuretic bumetanide, by 4,4'-diisothiocyano-2,2'-stilbenedisulfonate (DIDS) and ... are consistent with the transport of glisoxepide via the transport system for the unconjugated bile acid …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Categories: … Alimentary Tract and Metabolism …
Edetate copper disodium
Experimental
Carbenoxolone
An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity. [PubChem]
Experimental
Matched Iupac: … 9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid …
Matched Categories: … Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Categories: … Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Omapatrilat
Omapatrilat is an investigational drug that inhibits both neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE). The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating blood vessels, and reducing preload and ventricular remodeling. This drug from BMS was not approved by the FDA due...
Investigational
Matched Iupac: … -oxo-4-[(2S)-3-phenyl-2-sulfanylpropanamido]-octahydro-2H-pyrido[2,1-b][1,3]thiazepine-7-carboxylic acid …
Matched Description: … The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating ... blood vessels, and reducing preload and ventricular remodeling. ... Omapatrilat is an investigational drug that inhibits both neutral endopeptidase (NEP) and angiotensin …
Matched Description: … The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating ... blood vessels, and reducing preload and ventricular remodeling. ... Omapatrilat is an investigational drug that inhibits both neutral endopeptidase (NEP) and angiotensin …
Ethoxzolamide
Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confers the risk for hypokalemia.
Withdrawn
Matched Description: … Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. ... It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium …
Cariporide
Investigational
Astodrimer
Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.
Investigational
Matched Description: … It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups. ... Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. …
Matched Salts name: … Astodrimer Sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Salts name: … Astodrimer Sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Volixibat
Volixibat, also known as SHP626 or LUM002, is an investigational drug that will potentially be used for the treatment of Non-Alcoholic Steatohepatitis (NASH). If approved for use, it will be the first available agent for the treatment of NASH.
Volixibat is a selective inhibitor of the apical sodium-dependent bile acid...
Experimental
Investigational
Matched Iupac: … tetrahydro-1lambda6-benzothiepin-5-yl]phenyl}carbamoyl)amino]-3,5-dihydroxyoxan-2-yl]methoxy}sulfonic acid …
Matched Description: … Volixibat is a selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT), a transmembrane ... Also known as the ileal bile acid transporter (IBAT), ASBT is primarily responsible for the enterohepatic ... recirculation of bile acids and ultimately for hepatic lipid and glucose metabolism [A32120]. …
Matched Description: … Volixibat is a selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT), a transmembrane ... Also known as the ileal bile acid transporter (IBAT), ASBT is primarily responsible for the enterohepatic ... recirculation of bile acids and ultimately for hepatic lipid and glucose metabolism [A32120]. …
Saprisartan
Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan. It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism .
Experimental
Pirenoxine
Experimental
Matched Iupac: … 4-hydroxy-12-oxo-12H-10-oxa-1,5-diazatetraphene-2-carboxylic acid …
Matched Salts name: … Pirenoxine sodium …
Matched Salts name: … Pirenoxine sodium …
Methyclothiazide
A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)
Withdrawn
Matched Categories: … methyclothiazide and potassium ... Sodium Chloride Symporter Inhibitors …
Acifluorfen
Acifluorfen is a protoporphyrinogen oxidase inhibitor.
Experimental
Matched Iupac: … 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoic acid …
Matched Salts name: … Acifluorfen sodium …
Matched Salts name: … Acifluorfen sodium …
Bevasiranib
Bevasiranib is a small interfering RNA (siRNA) targeting vascular endothelial growth factor A (VEGF-A).
Investigational
Matched Salts name: … Bevasiranib sodium …
Matched Categories: … Nucleic Acid Probes ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acid Probes ... Nucleic Acids, Nucleotides, and Nucleosides …
Ecabet
Ecabet is a prescription eye drop for the treatment of dry eye syndrome. Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia. Mucin is a glycoprotein component of tear film that lubricates while retarding moisture loss...
Investigational
Matched Iupac: … ,10aR)-1,4a-dimethyl-7-(propan-2-yl)-6-sulfo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid …
Matched Description: … by conjunctival goblet cells and corneal epithelia. ... Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced ... Ecabet is currently marketed in Japan as an oral agent for treatment of gastric ulcers and gastritis. …
Matched Salts name: … Ecabet sodium …
Matched Description: … by conjunctival goblet cells and corneal epithelia. ... Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced ... Ecabet is currently marketed in Japan as an oral agent for treatment of gastric ulcers and gastritis. …
Matched Salts name: … Ecabet sodium …
Tonapofylline
Tonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and Congestive Heart Failure.
Investigational
Matched Iupac: … 3-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)bicyclo[2.2.2]octan-1-yl]propanoic acid …
Matched Description: … Tonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and …
Matched Description: … Tonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and …
Refametinib
Investigational
Cridanimod
Experimental
Matched Iupac: … 2-(9-oxo-9,10-dihydroacridin-10-yl)acetic acid …
Matched Salts name: … Cridanimod sodium …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Salts name: … Cridanimod sodium …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Tetrodotoxin
An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order tetraodontiformes, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction. Tetrodotoxin is being investigated by Wex Pharmaceuticals for the treatment of chronic and breakthrough pain in advanced cancer patients as...
Investigational
Matched Description: … The toxin causes paresthesia and paralysis through interference with neuromuscular conduction. ... Tetrodotoxin is being investigated by Wex Pharmaceuticals for the treatment of chronic and breakthrough ... An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order tetraodontiformes …
Matched Categories: … Sodium Channel Blockers …
Matched Categories: … Sodium Channel Blockers …
Idraparinux
Idraparinux, a synthetic pentasaccharide is an antithrombin-dependent inhibitor of activated factor X. It was developed for the treatment and prevention of thromboembolic events. However, clinical trials have revealed that idraparinux had lead to bleeding. As a result, Sanofi stopped the development of the drug.
Investigational
Matched Iupac: … dimethoxy-3-{[(2R,3R,4S,5R,6R)-3,4,5-trimethoxy-6-[(sulfooxy)methyl]oxan-2-yl]oxy}oxane-2-carboxylic acid …
Matched Description: … It was developed for the treatment and prevention of thromboembolic events. …
Matched Salts name: … Idraparinux sodium …
Matched Description: … It was developed for the treatment and prevention of thromboembolic events. …
Matched Salts name: … Idraparinux sodium …
Alisertib
Alisertib is a novel aurora A kinase inhibitor under investigation for the treatment of various forms of cancer.
Investigational
Matched Iupac: … 3,5,9-triazatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2,4,6,9,11,13-heptaen-4-yl]amino}-2-methoxybenzoic acid …
Matched Salts name: … Alisertib sodium …
Matched Salts name: … Alisertib sodium …
Larsucosterol
Investigational
Matched Iupac: … -1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl]oxidanesulfonic acid …
Matched Salts name: … Larsucosterol sodium …
Matched Salts name: … Larsucosterol sodium …
Tianeptine
Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) . Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants .
Tianeptine was discovered and...
Investigational
Matched Iupac: … 9lambda6-thia-10-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-yl}amino)heptanoic acid …
Matched Description: … Currently, tianeptine is approved in France and manufactured and marketed by Laboratories Servier SA; ... Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied ... Tianeptine was discovered and patented by The French Society of Medical Research in the 1960s [L2946] …
Matched Salts name: … Tianeptine sodium …
Matched Description: … Currently, tianeptine is approved in France and manufactured and marketed by Laboratories Servier SA; ... Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied ... Tianeptine was discovered and patented by The French Society of Medical Research in the 1960s [L2946] …
Matched Salts name: … Tianeptine sodium …
Displaying drugs 576 - 600 of 654 in total