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Displaying drugs 576 - 600 of 704 in total
Experimental
Matched Name: … O-(N-acetyl-alpha-D-galactosaminyl)-L-serine …
Matched Iupac: … (2S)-2-amino-3-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propanoic …
Experimental
Matched Name: … 2''-O-[N-(3-(aminopropyl)2-aminoethyl]paromomycin …
Matched Iupac: … }-6-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxolan-3-yl]oxy}oxane-3,4-diol ... [(1R,2R,3S,5R,6S)-3,5-diamino-2-{[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy
Experimental
Matched Synonyms: … 1-(3-O-phosphono-beta-L-arabinofuranosyl)Pyrimidine-2,4(1H,3H)-Dione …
Matched Iupac: … (2R,3S,4S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy
Experimental
Matched Synonyms: … Quinolin-2-ol ... Quinolin-2(1H)-one ... o-Aminocinnamic acid lactam …
Matched Iupac: … 1,2-dihydroquinolin-2-one
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Synonyms: … L-OHP
Matched Description: … [A797] Oxaliplatin was approved by the FDA on January 9, 2004 and is currently marketed by Sanofi-Aventis ... refractory to an initial fluorouracil and leucovorin combination. ... Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … AL OXA ® SOLUCION CONCENTRADA PARA INFUSION ... O-PLAT 50 MG POLVO LIOFILIZADO PARA INYECC ION ... O-PLAT 100 MG POLVO LIOFILIZADO PARA INYECCION …
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including...
Approved
Vet approved
Matched Synonyms: … S(O)Me2 …
Matched Description: … Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation ... of pharmaceuticals. ... Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application …
Matched Categories: … Genito Urinary System and Sex Hormones ... Topical Products for Joint and Muscular Pain ... Compounds used in a research, industrial, or household setting …
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and ... [L31998] Adenosine was granted FDA approval on 30 October 1989.[L31978] ... The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were …
Matched Mixtures name: … Lip And Hand Camellia ... Lip And Hand Wild Rose ... Lip And Hand Shea Butter …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … misoli Power Snail and Collagen Hydrog el Mask Pack ... rootree Treetherapy Rejuvenating Eye and Neck Treatment ... Oozoo Face Serum Alpha One Nutrient …
Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria. Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans.
Experimental
Vet approved
Matched Synonyms: … 4-O-(3α-amino-6α-((4-amino-4-deoxy-α-D-glucopyranosyl)oxy)-2,3,4,5aβ,6,7,8,8aα-octahydro-8β-hydroxy-7β ... 4-O-((8R)-2-amino-8-O-(4-amino-4-deoxy-α-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo …
Matched Iupac: … 5S,6S)-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy ... }-4-hydroxy-3-(methylamino)-octahydropyrano[3,2-b]pyran-2-yl]oxy}-5-amino-6-(hydroxymethyl)oxane-3,4- …
Matched Description: … Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria ... Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted …
Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness preceding suicide.[L5596,A175462] On March 5, 2019, the nasal spray drug, esketamine, also known as Spravato (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. Esketamine is the s-enantiomer of Ketamine. Ketamine...
Approved
Investigational
Matched Synonyms: … (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone …
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one
Matched Description: … Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness ... The intranasal route of administration for this drug allows for easy administration and a fast onset ... disorder who have not experienced an improvement in symptoms despite treatment with various medications and
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Synonyms: … O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine ... O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine …
Matched Description: … [F4633] T4 and T3 act on nearly every cell of the body, but have a particularly ... the thyroid hormones T4 (tetraiodothyronine or thyroxine) and T3 (triiodothyronine ... the physiological effects of the thyroid hormones; T4 and T3 have a relative potency …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... levothyroxine sodium and iodine compounds ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.
Experimental
Matched Synonyms: … Guanosine 5'-O-(3-thiotriphosphate) …
Matched Iupac: … )phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonothioic acid ... ({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Description: … proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes ... A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients...
Approved
Matched Description: … Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various ... and marketed by several pharmaceutical companies. ... when compared to unfractionated [heparin], without increasing the risk of serious bleeding. …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … KLEXANE 10000 IE 100MG O S ... KLEXANE 4000 IE 40MG O SI. ... KLEXANE 6000 IE 60MG O SI. …
Investigational
Matched Synonyms: … RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND
A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … (3-(o-chlorophenyl)-5-methyl-4-isoxazolyl)penicillin ... 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid ... (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1- …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Description: … A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin]. …
Matched Categories: … combinations of penicillins …
Experimental
Matched Synonyms: … 3'-O-Methylquercetin …
Matched Iupac: … 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one
Experimental
Matched Name: … 2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose …
Experimental
Matched Name: … 1-(O-Carboxy-Phenylamino)-1-Deoxy-D-Ribulose-5-Phosphate …
Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose …
Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Synonyms: … Hexadeca-μ-hydroxytetracosahydroxy[μ8-[1,3,4,6-tetra-O-sulfo-β-Dfructofuranosyl-α-D-glucopyranoside tetrakis …
Matched Iupac: … )oxy]sulfonyl}oxy)methyl]oxolan-2-yl]oxy}-4,5-bis({[(dihydroxyalumanyl)oxy]sulfonyl}oxy)-2-[({[(dihydroxyalumanyl ... )oxy]sulfonyl}oxy)methyl]oxan-3-yl]oxy}sulfonyl)oxy]alumanediol alumanetriol hydrate ... [({[(2R,3R,4S,5R,6R)-6-{[(2S,3S,4R,5R)-3,4-bis({[(dihydroxyalumanyl)oxy]sulfonyl}oxy)-2,5-bis[({[(dihydroxyalumanyl …
Matched Description: … Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal ... It is sold under many brands and is available in both tablet and suspension forms. ... Sucralfate has been shown to be a well-tolerated and safe drug. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Synonyms: … [4.2.0]oct-2-ene-2-carboxylic acid ... aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... -thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … -thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5 …
Matched Description: … In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. ... Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and
Matched Products: … Cefotaxime and Dextrose …
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Synonyms: … Bicarbonate of soda …
Matched Description: … powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and
Matched Mixtures name: … Care One Original Antacid and Pain Relief ... Zegerid OTC ... Zegerid OTC
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Arm and Hammer Baking Soda ... BAKING SODIO OSA
A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Synonyms: … 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl ... )furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one ... 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside) …
Matched Iupac: … 15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy ... hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one
Matched Description: … Etoposide acts primarily in the G2 and S phases of the cell cycle. ... Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death ... Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Investigational
Matched Synonyms: … (+/-)-o-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoxime …
Experimental
Matched Name: … 1-O-Octyl-2-Heptylphosphonyl-Sn-Glycero-3-Phosphoethanolamine …
Matched Iupac: … (2-aminoethoxy)[(2R)-2-{[heptyl(hydroxy)phosphoryl]oxy}-3-(octyloxy)propoxy]phosphinic acid …
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It inhibits gastric acid secretion, as well as pepsin and gastrins output. ... Cimetidine has a range of pharmacological actions. ... It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Up and Up Acid Reducer …
Displaying drugs 576 - 600 of 704 in total