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Displaying drugs 51 - 75 of 2958 in total
Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins, DNA and RNA. Trichloroacetate is also found in cosmetic treatments and...
Approved
Matched Description: … , DNA and RNA. ... Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with ... In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins …
Matched Salts name: … Trichloroacetic acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Trichloroacetic Acid
Matched Products: … Trichloroacetic Acid 30% ... Trichloroacetic Acid 15% ... Trichloroacetic Acid 50% …
Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... are D-amino acids. ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Name: … Fenofibric acid
Matched Iupac: … 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid
Matched Description: … Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia ... ], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed ... , and mixed dyslipidemia. …
Matched Categories: … Acids, Acyclic ... Fibric Acids ... Carboxylic Acids ... Peroxisome Proliferator Receptor alpha Agonist ... Lipid Modifying Agents …
Matched Products: … Fenofibric Acid ... Fenofibric acid ... Fenofibric Acid Delayed-Release …
Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective...
Approved
Matched Description: … It manages and prevents dental caries and gingivitis by promoting enamel mineralization [A19580], reducing ... compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and ... effect and modulation of the microbial composition of the dental biofilm [A19581]. …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up Anticavity Toothpaste Multi Function ... Sensodyne Sensitivity and Gum Clean and Fresh ... Crest Sensi-Repair and Prevent …
Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational
Matched Synonyms: … Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13) …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in …
Penicillium glaucum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, penicillium glaucum ... Molds, rusts and smuts, penicillium glaucus …
Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids ... It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous ... the activity-related kringle-2 and serine protease domains of human tPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … enhanced secretion of bile acids and lipids in the feces, patients who take complicated medication regimens ... Bile acid sequestrants like colestipol have been in use since the 1970s. ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated …
Matched Salts name: … Colestipol hydrochloride
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity ... Medications that reduce magnesium levels ... Lipid Modifying Agents ... Lipid Regulating Agents …
Matched Products: … Colestipol Hydrochloride ... Colestipol hydrochloride
Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Synonyms: … Acide carglumique ... Carglumic acid ... Acidum carglumicum …
Matched Name: … Carglumic acid
Matched Iupac: … (2S)-2-(carbamoylamino)pentanedioic acid
Matched Description: … Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. ... cause neurologic problems, cerebral edema, coma, and death. ... Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl …
Matched Categories: … Amino Acids and Derivatives ... Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids
Matched Products: … Carglumic Acid ... Carglumic acid ... ACIDO CARGLUMICO WAYMADE …
Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form ... NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... NOVOSEVEN 1MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... powder and solvent for solution for injection 2mg …
Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Approved
Matched Synonyms: … Phosphorofluoridic acid, disodium salt …
Matched Mixtures name: … Chunzam Silk Amino Acid Tooth ... Mentadent Specialty Whitening Toothpaste and Polishing ... Hawaiian Airline EC with Colgate Toothbrush and Sun …
Matched Categories: … Alimentary Tract and Metabolism ... Acids ... Acids, Noncarboxylic ... Phosphoric Acids ... Phosphorus Acids
Matched Products: … Colgate Sparkling White Mint Zing ... Escopinio PHYTO alpha Toothpaste ... My Earthday Alpha Care Plus …
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … the pupil,[L9413] and induce local vasoconstriction. ... Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Mixtures name: … Neo Citran Powder ... Neo Citran A Powder ... Neo Citran Nutrasweet …
Matched Salts name: … Phenylephrine hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics ... phenylephrine and ketorolac ... Adrenergic alpha-Agonists …
Matched Products: … CareOne Cold and Sinus ... Up and Up Sinus PE ... Up and Up nasal decongestant PE …
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Synonyms: … Ibandronic acid
Matched Iupac: … {1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl}phosphonic acid
Matched Description: … ], [minodronic acid], and [risedronic acid]. ... [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis. ... Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid
Matched Categories: … ibandronic acid and colecalciferol ... Drugs Affecting Bone Structure and Mineralization ... ibandronic acid
Matched Products: … ACIDO IBANDRONICO ARROW ... ACIDO IBANDRONICO SUN ... ACIDO IBANDRONICO AVANSOR …
NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … gene and messenger RNA (mRNA000042) encoding Cas9. ... NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 …
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (40 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …
Approved
Investigational
Matched Products: … AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000IU/VIAL …
Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …
Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Description: … Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and ... It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. …
Matched Mixtures name: … Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN …
Matched Products: … Suave Cocoa Butter Antiperspirant and Deodorant ... Axe Touch Antiperspirant and Deodorant ... Suave IS Sweet Pea and Violet Antiperspirant and Deodorant …
Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein ... Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …
DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and
CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Phosphatidic Acids
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Acide retinoique ... Retinoic acid ... Retionic acid
Matched Iupac: … (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Matched Description: … Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin ... activates nuclear receptors to regulate epithelial cell growth and differentiation. ... [A257689] Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging …
Matched Mixtures name: … Ascorbyl Palmitate 2% / Hyaluronic Acid Sodium Salt 0.2% / Niacinamide 5% / Tretinoin 0.025% ... Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4% / Tretinoin 0.1% ... Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4% / Tretinoin 0.05% …
Matched Categories: … Cell Stimulants and Proliferants ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Vitamin A Acid ... ACIDO RETINOICO ... Vitamin A Acid 0.1% Cream …
Eupatorium capillifolium pollen is the pollen of the Eupatorium capillifolium plant. Eupatorium capillifolium pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Dog Fennel, Eastern Eupatorium capillifolium ... Pollens - Weeds and Garden Plants, Dog Fennel Eupatorium capillifolium …
Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It was also approved by FDA and EMA in 2016. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …
Displaying drugs 51 - 75 of 2958 in total