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Displaying drugs 851 - 875 of 1075 in total
Experimental
Matched Synonyms: … 6-Deoxy-2-O-methyl-beta-L-galactopyranose …
Matched Name: … 2-O-Methyl-beta-L-fucopyranose …
A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of adenylate cyclase.
Experimental
Matched Synonyms: … Guanosine 5'-[beta,gamma-imido]triphosphate …
Matched Description: … A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Epoetin beta ... Epoetina beta ... Epoetin beta rDNA …
Matched Description: … beta formulations. ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. ... The biosimilar is approved by the FDA and EMA as a safe, effective and affordable biological product …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for...
Approved
Matched Synonyms: … beta-5-Fluoro-2'-deoxyuridine ... 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil ... 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil …
Matched Description: … malignant neoplasms of the liver and gastrointestinal tract. ... It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to …
Matched Mixtures name: … RAMIPRIL BETA COMP 5/25MG ... RAMIPRIL BETA COMP2.5/12.5 …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... ramipril and felodipine ... ramipril and amlodipine ... ramipril and bisoprolol …
Matched Products: … RAMIPRIL BETA 5MG ... RAMIPRIL BETA 10MG ... RAMIPRIL BETA 2.5MG …
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and ... lead to high blood pressure. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … BOSENTAN BETA 125MG ... BOSENTAN BETA 62.5MG …
Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Investigational
Matched Synonyms: … Human anti-transforming growth factor beta 1 monoclonal antibody ... Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4- …
Matched Description: … Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta
Pantethine is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5) via addition of cysteamine. It consists of two molecules of pantetheine that form a dimer via disufide linkages, and acts as an intermediate in the production of Coenzyme A. Coenzyme A plays an essential role...
Approved
Investigational
Matched Synonyms: … D-Bis(N-pantothenyl-beta-aminoethyl) disulfide …
Matched Description: … It consists of two molecules of pantetheine that form a dimer via disufide linkages, and acts as an intermediate ... Coenzyme A plays an essential role as a cofactor in the metabolism of lipids and carbohydrates including ... Pantethine is available as a dietary supplement for lowering blood cholesterol and triglycerides. …
Matched Categories: … Alimentary Tract and Metabolism …
Experimental
Matched Synonyms: … 1-(3-O-sulfo-beta-D-galactosyl)-N-[(15Z)-tetracos-15-enoyl]sphingosine …
Investigational
Matched Synonyms: … Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Allopurinol riboside is a nucleoside analogue of allopurinol with a beta-D-ribofuranosyl moiety at the 1-position.
Investigational
Matched Synonyms: … 4h-pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-1-.beta.-d-ribofuranosyl- …
Matched Description: … Allopurinol riboside is a nucleoside analogue of [allopurinol] with a beta-D-ribofuranosyl moiety at …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases...
Approved
Investigational
Matched Description: … Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads ... to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. ... The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to …
Matched Categories: … Genito Urinary System and Sex Hormones ... alfuzosin and finasteride …
Matched Products: … ALFUZOSIN BETA 10MG RETARD …
Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma.
Investigational
Matched Synonyms: … 5'-O-(trans-9"-octadecenoyl)-1-beta-D-2'deoxy-2',2'-difluorocytidine ... 5'-O-(TRANS-9''-OCTADECENOYL)-1-.BETA.-D-2'DEOXY-2',2'-DIFLUOROCYTIDINE …
Matched Description: … been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Synonyms: … N-benzyl-beta-(isonicotinylhydrazino)propionamide ... N-benzyl-beta-(isonicotinoylhydrazine)propionamide ... N-Isonicotinoyl-N'(beta-N-benzylcarboxamidoethyl)hydrazine …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing …
Includes ortho-, meta-, and para-nitrophenylgalactosides. [PubChem]
Experimental
Matched Name: … 1-O-[O-Nitrophenyl]-Beta-D-Galactopyranose …
Matched Description: … Includes ortho-, meta-, and para-nitrophenylgalactosides. [PubChem] …
Experimental
Matched Name: … 4-O-methyl-beta-D-glucuronic acid …
Adenylic acid. Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. [PubChem]
Experimental
Matched Name: … Gamma-Arsono-Beta, Gamma-Methyleneadenosine-5'-Diphosphate …
Experimental
Matched Name: … Beta-1,2,3,4,6-Penta-O-Galloyl-D-Glucopyranose …
Experimental
Matched Name: … N-acetyl-N'-beta-D-glucopyranosyl urea …
Experimental
Matched Name: … (2s)-4-(Beta-Alanylamino)-2-Aminobutanoic Acid …
Experimental
Matched Name: … [4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE] …
Experimental
Matched Name: … PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE …
Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to...
Approved
Investigational
Withdrawn
Matched Description: … , Norway and Australia. ... liquid, and other drug products, and was withdrawn due to its association with potentially fatal agranulocytosis ... It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. …
Matched Products: … ALNEX
Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic...
Approved
Matched Synonyms: … 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside) …
Matched Description: … Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead ... Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... Teniposide acts primarily in the G2 and S phases of the cycle. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Experimental
Matched Synonyms: … L-Threo-alpha,beta-diaminobutyric acid …
Displaying drugs 851 - 875 of 1075 in total