Displaying drugs 901 - 925 of 1142 in total
Allopurinol riboside
Allopurinol riboside is a nucleoside analogue of allopurinol with a beta-D-ribofuranosyl moiety at the 1-position.
Investigational
Matched Synonyms: … 4h-pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-1-.beta.-d-ribofuranosyl- …
Matched Description: … Allopurinol riboside is a nucleoside analogue of [allopurinol] with a beta-D-ribofuranosyl moiety at …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … Allopurinol riboside is a nucleoside analogue of [allopurinol] with a beta-D-ribofuranosyl moiety at …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Molibresib
Molibresib is under investigation in clinical trial NCT01943851 (A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and Clinical Activity of GSK525762 in Subjects With Relapsed, Refractory Hematologic Malignancies).
Investigational
Matched Synonyms: … Bet inhibitor gsk525762 …
Matched Description: … NCT01943851 (A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and …
Matched Description: … NCT01943851 (A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and …
AVR-48
Investigational
Matched Synonyms: … 4-nitrophenyl-n-acetyl-beta-d-glucosaminide ... 4-nitrophenyl 2-acetamido-2-deoxy-beta-d-glucopyranoside ... .beta.-d-glucopyranoside, 4-nitrophenyl 2-(acetylamino)-2-deoxy- …
Gemcitabine elaidate
Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma.
Investigational
Matched Synonyms: … 5'-O-(trans-9"-octadecenoyl)-1-beta-D-2'deoxy-2',2'-difluorocytidine ... 5'-O-(TRANS-9''-OCTADECENOYL)-1-.BETA.-D-2'DEOXY-2',2'-DIFLUOROCYTIDINE …
Matched Description: … been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Nialamide
Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Synonyms: … N-benzyl-beta-(isonicotinylhydrazino)propionamide ... N-benzyl-beta-(isonicotinoylhydrazine)propionamide ... N-Isonicotinoyl-N'(beta-N-benzylcarboxamidoethyl)hydrazine …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing …
Azacitidine
Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Synonyms: … 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one …
Matched Description: … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and ... inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and ... inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Citalopram
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Description: … It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing ... and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors. ... A14720] Citalopram enhances serotonergic transmission through the inhibition of serotonin reuptake, and …
Matched Products: … CITALOPRAM BETA 20MG FILMT ... CITALOPRAM BETA 30MG FILMT ... CITALOPRAM BETA 40MG FILMT …
Matched Products: … CITALOPRAM BETA 20MG FILMT ... CITALOPRAM BETA 30MG FILMT ... CITALOPRAM BETA 40MG FILMT …
Celastrol
Celastrol is a pentacyclic triterpenoid isolated from the root extracts of Tripterygium wilfordii.
Investigational
Matched Synonyms: … .,14.beta.,20.alpha ... 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, (9.beta.,13.alpha …
Lamotrigine
Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It...
Approved
Investigational
Matched Description: … It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. ... Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval ... [A191350]
Lamotrigine has relatively few side-effects and does not require laboratory monitoring. …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … LAMOTRIGIN BETA 50MG TABL ... LAMOTRIGIN BETA 100MG TABL ... LAMOTRIGIN BETA 200MG TABL …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … LAMOTRIGIN BETA 50MG TABL ... LAMOTRIGIN BETA 100MG TABL ... LAMOTRIGIN BETA 200MG TABL …
5beta-dihydrotestosterone
Experimental
Matched Synonyms: … 5-beta-DHT ... etiocholan-17-beta-ol-3-one …
Matched Categories: … Testosterone and derivatives …
Matched Categories: … Testosterone and derivatives …
(2S)-2,3-Diaminobutanoic acid
Experimental
Matched Synonyms: … L-Threo-alpha,beta-diaminobutyric acid …
Teniposide
Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic...
Approved
Matched Synonyms: … 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside) …
Matched Description: … Teniposide acts primarily in the G2 and S phases of the cycle. ... Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Teniposide acts primarily in the G2 and S phases of the cycle. ... Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
1-O-[O-Nitrophenyl]-Beta-D-Galactopyranose
Includes ortho-, meta-, and para-nitrophenylgalactosides. [PubChem]
Experimental
Matched Name: … 1-O-[O-Nitrophenyl]-Beta-D-Galactopyranose …
Matched Description: … Includes ortho-, meta-, and para-nitrophenylgalactosides. [PubChem] …
Matched Description: … Includes ortho-, meta-, and para-nitrophenylgalactosides. [PubChem] …
Gamma-Arsono-Beta, Gamma-Methyleneadenosine-5'-Diphosphate
Adenylic acid. Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. [PubChem]
Experimental
Matched Name: … Gamma-Arsono-Beta, Gamma-Methyleneadenosine-5'-Diphosphate …
Beta-1,2,3,4,6-Penta-O-Galloyl-D-Glucopyranose
Experimental
Matched Name: … Beta-1,2,3,4,6-Penta-O-Galloyl-D-Glucopyranose …
N-acetyl-N'-beta-D-glucopyranosyl urea
Experimental
Matched Name: … N-acetyl-N'-beta-D-glucopyranosyl urea …
(2s)-4-(Beta-Alanylamino)-2-Aminobutanoic Acid
Experimental
Matched Name: … (2s)-4-(Beta-Alanylamino)-2-Aminobutanoic Acid …
[4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE]
Experimental
Matched Name: … [4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE] …
PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE
Experimental
Matched Name: … PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE …
Esculin
Esculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum). Esculin belongs to the family of Glycosyl...
Approved
Matched Synonyms: … 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-cumarin ... 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one …
Matched Description: … naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and …
Matched Description: … naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and …
Hemicellulase
Experimental
Matched Synonyms: … Endo-1,4-beta-xylanase A …
Matched Categories: … Enzymes and Coenzymes …
Matched Categories: … Enzymes and Coenzymes …
Timolol
Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Description: … of conditions such as open-angle glaucoma and hypertension. ... [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management ... Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate …
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... Antiglaucoma Preparations and Miotics ... timolol and thiazides ... timolol, thiazides and other diuretics …
Matched Products: … Beta-tim - 0.5% Liq ... Beta-tim - 0.25% Liq …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate …
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... Antiglaucoma Preparations and Miotics ... timolol and thiazides ... timolol, thiazides and other diuretics …
Matched Products: … Beta-tim - 0.5% Liq ... Beta-tim - 0.25% Liq …
Mirtazapine
Mirtazapine is a tetracyclic piperazino-azepine antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.[T595, L6157] The effects of this...
Approved
Matched Description: … It may improve the symptoms of neurological disorders, reverse weight loss caused by medical conditions ... , improve sleep, and prevent nausea and vomiting after surgery. ... ., and received FDA approval in 1997 for the treatment of major depressive disorder. …
Matched Products: … MIRTAZAPIN BETA 15MG ... MIRTAZAPIN BETA 30MG ... MIRTAZAPIN BETA 45MG …
Matched Products: … MIRTAZAPIN BETA 15MG ... MIRTAZAPIN BETA 30MG ... MIRTAZAPIN BETA 45MG …
Displaying drugs 901 - 925 of 1142 in total