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Displaying drugs 926 - 945 of 945 in total

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced ... drugs like [diltiazem] and [flunarizine], but is chemically unrelated to other cardioactive medications ... [L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer …
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil ... Calcium Channel Blockers ... Calcium Channel Blockers (Nondihydropyridine) …
Matched Products: … VERAPAMILO TABLETAS RECUBIERTAS POR 120 MG …

Doxorubicin

Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … DOXORUBICINA SOLUCION PARA INYECCION VIAL POR 50 MG/25 ML …

Donepezil

In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and ... Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … Septa Donepezil ... ANDEM 10 MG FILM TABLET, 14 ADET ... ANDEM 10 MG FILM TABLET, 28 ADET …

Metamizole

Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to...
Approved
Investigational
Withdrawn
Matched Description: … [A251805] Metamizole is still used in certain countries in Europe, Asia and South America.[A251805] ... liquid, and other drug products, and was withdrawn due to its association with potentially fatal agranulocytosis ... , Norway and Australia. …
Matched Products: … DIPIRONA 1 GAMPOLLA POR 2 ML …

Metronidazole

Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Description: … , and amebiasis which are parasitic infections. ... It is available in capsule form, tablet form, and topical form, and suppository preparations for the ... [L3754] It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride ... Bismuth subcitrate potassium, Metronidazole, Tetracycline hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment ... Antiparasitic Products, Insecticides and Repellents ... metronidazole and diloxanide ... Genito Urinary System and Sex Hormones …
Matched Products: … METRONIDAZOL 0.5% GLAS …

Diltiazem

Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... into cardiac and vascular smooth muscle during depolarization. ... under various brand names with Cardizem and Tiazac being the most common ones. …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Calcium Channel Blockers ... Calcium Channel Blockers (Nondihydropyridine) ... Miscellaneous Calcium-channel Blocking Agents …
Matched Products: … DILTIAZEM TABLETAS POR 60 MG …

Beclomethasone dipropionate

Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched Description: … Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone ... later in a dry powder inhaler and an aqueous nasal spray. ... Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is rapidly …
Matched Mixtures name: … Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation …
Matched Categories: … Adrenals ... Adrenal Cortex Hormones ... Alimentary Tract and Metabolism ... beclometasone and antibiotics ... formoterol and beclometasone …
Matched Products: … NABUMEX®INHALADOR 50MCG POR DOSIS …

Fluorouracil

A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Fluorouracil and prodrugs ... Skin and Mucous Membrane Agents …
Matched Products: … 5 FU LIV PHARMA 50MG/ML …

Valproic acid

Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Description: … Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for ... [L6190] Since then, it has been investigated for neuroprotective, anti-manic, and anti-migraine effects …
Matched Products: … ACIDO VALPROICO 100 MG/ ML POR 5 ML …

Furosemide

Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... failure, renal failure, and high blood pressure. …
Matched Categories: … furosemide and potassium ... furosemide and potassium-sparing agents ... High-Ceiling Diuretics and Potassium-Sparing Agents ... Non Potassium Sparing Diuretics ... Sodium Potassium Chloride Symporter Inhibitors …
Matched Products: … FUROSEMIDA TABLETAS POR 40 MG …

Lamotrigine

Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It...
Approved
Investigational
Matched Description: … It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. ... Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval ... [A191350] Lamotrigine has relatively few side-effects and does not require laboratory monitoring. …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers …
Matched Products: … LAMOTRIGINA POR 200 MG …

Metformin

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Mixtures name: … Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... metformin and sulfonylureas ... metformin and gemigliptin ... metformin and linagliptin …
Matched Products: … Septa-metformin …

Pregabalin

Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Description: … [A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other ... [A187190,L7066] Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended ... there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent calcium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … DOLICA® CAPSULAS POR 75 MG ... DOLICA® CAPSULAS POR 300 MG ... DOLICA® CAPSULAS POR 150 MG …

Hexachlorophene

A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
Approved
Withdrawn
Matched International brands: … Septi-soft …
Matched Description: … It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …

Budesonide

Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Description: … of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. ... Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Adrenals ... Alimentary Tract and Metabolism ... Adrenal Cortex Hormones ... formoterol and budesonide ... salmeterol and budesonide …
Matched Products: … BUDESONIDA 0.5 MG/2ML SUSPENSION PARA INHALAR POR NEBULIZACION …

Methotrexate

Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Description: … inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and ... Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … METOTREXATO PARA INYECCION POR 50 MG /2ML (SOLUCION INYECTABLE) …

Tadalafil

Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Description: … that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and ... [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. ... In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and …
Matched Categories: … Genito Urinary System and Sex Hormones ... ambrisentan and tadalafil ... tamsulosin and tadalafil ... finasteride and tadalafil ... macitentan and tadalafil …
Matched Products: … LUDIKA TABLETAS RECUBIERTAS POR 20 MG …

Clarithromycin

Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug...
Approved
Matched Description: … translation and protein assembly process. ... Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the ... Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration …
Matched Mixtures name: … Lansoprazole, Amoxicillin, and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin …
Matched Categories: … Alimentary Tract and Metabolism ... Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins ... Metabolic Side Effects of Drugs and Substances ... vonoprazan, amoxicillin and clarithromycin …
Matched Products: … CLORMICIN125 POR CADA 5 ML …

Trimebutine

Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI...
Approved
Matched International brands: … Yuan Sheng Li Wei …
Matched Description: … Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal ... pain with antimuscarinic and weak mu opioid agonist effects. ... It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium Channel Blockers …

Roxithromycin

Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is...
Approved
Investigational
Withdrawn
Matched International brands: … Ao Ge Shen …
Matched Description: … Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar ... Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with ... It is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Displaying drugs 926 - 945 of 945 in total