Displaying drugs 1076 - 1100 of 1187 in total
Pravastatin
Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Description: … It was the first statin administered as the active form and not as a prodrug. ... Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin]. ... The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation …
Matched Categories: … pravastatin and ezetimibe ... pravastatin and fenofibrate ... pravastatin and acetylsalicylic acid ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … COL-ALPHAR ... Ipg-pravastatin …
Matched Categories: … pravastatin and ezetimibe ... pravastatin and fenofibrate ... pravastatin and acetylsalicylic acid ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … COL-ALPHAR ... Ipg-pravastatin …
Entacapone
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of...
Approved
Investigational
Matched Synonyms: … (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide …
Matched Description: … and a decarboxylase inhibitor. ... When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased ... and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa …
Matched Mixtures name: … Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone …
Matched Description: … and a decarboxylase inhibitor. ... When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased ... and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa …
Matched Mixtures name: … Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone …
Pecan
Pecan allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Carya illinoinensis seed …
Matched Description: … Pecan allergenic extract is used in allergenic testing. …
Matched Description: … Pecan allergenic extract is used in allergenic testing. …
Dactinomycin
A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Synonyms: … ACTINOMYCIN I1 ... Actinomycin IV ... amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i) …
Matched Iupac: … 10S,13R,18aS)-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-6,13-bis(propan-2-yl)-hexadecahydro-1H-pyrrolo[2,1-i] …
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than ... A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Iupac: … 10S,13R,18aS)-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-6,13-bis(propan-2-yl)-hexadecahydro-1H-pyrrolo[2,1-i] …
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than ... A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
2-KETO-6-PHOSPHATE-D-GLUCONIC ACID, ALPHA-FURANOSE FORM
Experimental
Matched Name: … 2-KETO-6-PHOSPHATE-D-GLUCONIC ACID, ALPHA-FURANOSE FORM …
Inolimomab
Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain …
Matched Description: … It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a ... Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a ... Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mirvetuximab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human folate receptor .alpha.) …
Prostaglandin D2
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
Investigational
Matched Synonyms: … 11-Dehydroprostaglandin F2-alpha …
Matched Description: … It is released upon activation of mast cells and is also synthesized by alveolar macrophages. ... , and cytotoxic effects. ... Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory …
Matched Description: … It is released upon activation of mast cells and is also synthesized by alveolar macrophages. ... , and cytotoxic effects. ... Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory …
Streptomycin
Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Synonyms: … 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl) …
Matched Description: … has fallen out of favor due to resistance and is now primarily used as adjunctive treatment in cases ... Medicine for their discovery of streptomycin and its antibacterial activity. ... [A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in …
Matched Categories: … Alimentary Tract and Metabolism ... streptomycin and isoniazid …
Matched Description: … has fallen out of favor due to resistance and is now primarily used as adjunctive treatment in cases ... Medicine for their discovery of streptomycin and its antibacterial activity. ... [A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in …
Matched Categories: … Alimentary Tract and Metabolism ... streptomycin and isoniazid …
Yellow fever vaccine
Yellow fever vaccine prevents against Yellow Fever, a viral hemorrhagic disease caused by the transmission of a flavivirus through the bite of an infected mosquito. Symptoms of Yellow fever can range from asymptomatic, to mild flu-like illness, to more severe symptoms such as shock, jaundice, internal bleeding, and organ failure...
Approved
Investigational
Matched Synonyms: … Flavivirus yellow fever virus 17D-204 whole …
Matched Description: … areas and for laboratory personnel who handle virulent yellow fever virus or concentrated preparations ... Yellow Fever is most commonly found in the southern hemisphere, in tropical regions of Africa and Central ... It is composed of two live, attenuated strains of yellow fever virus, 17D-204 and 17DD, which have been …
Matched Products: … STAMARIL 0,5 ML IM/SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON VE ÇÖZÜCÜ İÇEREN KULLANIMA HAZIR ENJEKTÖR ... STAMARIL 0,5 ML IM/SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON VE ÇÖZÜCÜ İÇEREN KULLANIMA HAZIR ENJEKTÖR …
Matched Description: … areas and for laboratory personnel who handle virulent yellow fever virus or concentrated preparations ... Yellow Fever is most commonly found in the southern hemisphere, in tropical regions of Africa and Central ... It is composed of two live, attenuated strains of yellow fever virus, 17D-204 and 17DD, which have been …
Matched Products: … STAMARIL 0,5 ML IM/SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON VE ÇÖZÜCÜ İÇEREN KULLANIMA HAZIR ENJEKTÖR ... STAMARIL 0,5 ML IM/SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON VE ÇÖZÜCÜ İÇEREN KULLANIMA HAZIR ENJEKTÖR …
Nerinetide
Na 1 is under investigation in clinical trial NCT00728182 (Evaluating Neuroprotection in Aneurysm Coiling Therapy).
Investigational
Matched Synonyms: … H-TYR-GLY-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARG-LYS-LEU-SER-SER-ILE-GLU-SER-ASP-VAL-OH ... TYR-GLY-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARG-LYS-LEU-SER-SER-ILE-GLU-SER-ASP-VAL ... -GLUTAMYL-L-SERYL-L-.ALPHA.-ASPARTYL- …
Matched Description: … Na 1 is under investigation in clinical trial NCT00728182 (Evaluating Neuroprotection in Aneurysm Coiling …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Na 1 is under investigation in clinical trial NCT00728182 (Evaluating Neuroprotection in Aneurysm Coiling …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Segesterone acetate
Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 . In animal studies, segesterone acetate was shown to be one of the most potent progestins . It mediates progestational activity 100 times higher than that of progesterone ....
Approved
Experimental
Investigational
Matched Synonyms: … 16-Methylene-17-alpha-acetoxy-19-nor-4-pregnene-3,20-dione …
Matched Description: … It is commonly sold under the brand names Nestorone and Elcometrine and serves as an active component ... Annovera™ is administered as a vaginal ring that is in place for 21 days and removed for 7 days each ... Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … It is commonly sold under the brand names Nestorone and Elcometrine and serves as an active component ... Annovera™ is administered as a vaginal ring that is in place for 21 days and removed for 7 days each ... Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Uridine-5'-diphosphate-2-deoxy-2-fluoro-alpha-D-galactose
Experimental
Matched Name: … Uridine-5'-diphosphate-2-deoxy-2-fluoro-alpha-D-galactose …
2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose
Experimental
Matched Name: … 2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose …
2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose
Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose …
4-NITROPHENYL-(6-S-ALPHA-D-XYLOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE
Experimental
Matched Name: … 4-NITROPHENYL-(6-S-ALPHA-D-XYLOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE …
Dienogest
Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not...
Approved
Matched Synonyms: … 17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one …
Matched Description: … form pills approved in United States and Europe however it is not available in the US by itself. ... It is a derivative of 19-nortestosterone and has antiandrogenic properties. ... In Europe, Australia, Malaysia, Singapore and Japan, dienogest single therapy is an approved treatment …
Matched Mixtures name: … Estradiol Valerate and Estradiol Valerate/Dienogest ... Estradiol Valerate and Estradiol Valerate/Dienogest …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... dienogest and estrogen ... dienogest and estradiol ... Genito Urinary System and Sex Hormones ... dienogest and ethinylestradiol …
Matched Description: … form pills approved in United States and Europe however it is not available in the US by itself. ... It is a derivative of 19-nortestosterone and has antiandrogenic properties. ... In Europe, Australia, Malaysia, Singapore and Japan, dienogest single therapy is an approved treatment …
Matched Mixtures name: … Estradiol Valerate and Estradiol Valerate/Dienogest ... Estradiol Valerate and Estradiol Valerate/Dienogest …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... dienogest and estrogen ... dienogest and estradiol ... Genito Urinary System and Sex Hormones ... dienogest and ethinylestradiol …
Epirubicin
An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Synonyms: … 5,12-NAPHTHACENEDIONE, 10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA. ... 1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO-2,3,6-TRIDEOXY-.ALPHA …
Matched Description: … The compound exerts its antitumor effects by interference with the synthesis and function of DNA. ... An anthracycline which is the 4'-epi-isomer of doxorubicin. …
Matched Categories: … Anthracyclines and Related Substances ... Topoisomerase II Inhibitors ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Pharmorubicin Rdf Inj 50mg/vial ... ANTHRACIN 10MG/5ML IV ENFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... ANTHRACIN 50MG/25ML IV ENFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …
Matched Description: … The compound exerts its antitumor effects by interference with the synthesis and function of DNA. ... An anthracycline which is the 4'-epi-isomer of doxorubicin. …
Matched Categories: … Anthracyclines and Related Substances ... Topoisomerase II Inhibitors ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Pharmorubicin Rdf Inj 50mg/vial ... ANTHRACIN 10MG/5ML IV ENFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... ANTHRACIN 50MG/25ML IV ENFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …
Acriflavine
Experimental
Matched Iupac: … 3,6-diamino-10-methylacridin-10-ium acridine-3,6-diamine chloride …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Matched Products: … APP YELLOW SOLUTION 0.5% …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Matched Products: … APP YELLOW SOLUTION 0.5% …
Alanine
Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.
Nutraceutical
Matched Synonyms: … L-alpha-Alanine …
Matched Description: … It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue ... , brain, and the central nervous system. ... Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... NUTRIPLUS LIPID SENZA ELETTROLITI …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue ... , brain, and the central nervous system. ... Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... NUTRIPLUS LIPID SENZA ELETTROLITI …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Peginterferon alfa-2a
Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Synonyms: … PEG-IFN alfa-2A ... Pegylated interferon alpha-2a …
Matched Description: … being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. ... Peginterferon alfa-2a is derived from the alfa-2a moeity of recombinant human interferon and acts by ... neuropsychiatric complications, and increased risk of hepatic decompensation in patients with cirrhosis …
Matched Categories: … Interferon alpha ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Interferon Type I …
Matched Description: … being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. ... Peginterferon alfa-2a is derived from the alfa-2a moeity of recombinant human interferon and acts by ... neuropsychiatric complications, and increased risk of hepatic decompensation in patients with cirrhosis …
Matched Categories: … Interferon alpha ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Interferon Type I …
NB-124 sulfate
Investigational
Matched Synonyms: … -d-allofuranosyl-(1->5)-o-(2-amino-2,7-dideoxy-d-glycero-.alpha. ... 6'-(r)-methyl-5-o-(5-amino-5,6-dideoxy-alpha-l-talofuranosyl)-paromamine sulfate …
Thalidomide
A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of inflammatory disorders and cancers. Thalidomide displays immunosuppressive and anti-angiogenic activity through modulating the release of inflammatory mediators like tumor necrosis factor-alpha...
Approved
Investigational
Withdrawn
Matched Synonyms: … alpha-N-Phthalylglutaramide ... alpha-(N-Phthalimido)glutarimide …
Matched Description: … inflammatory mediators like tumor necrosis factor-alpha (TNF-a) and other cytokine action. ... It has been reintroduced and used for a number of inflammatory disorders and cancers. ... enrol in the THALIDOMID Risk Evaluation and Mitigation Strategy (REMS) program to ensure contraception …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … inflammatory mediators like tumor necrosis factor-alpha (TNF-a) and other cytokine action. ... It has been reintroduced and used for a number of inflammatory disorders and cancers. ... enrol in the THALIDOMID Risk Evaluation and Mitigation Strategy (REMS) program to ensure contraception …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Isoleucine
An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.
Investigational
Nutraceutical
Matched Synonyms: … Ile ... alpha-amino-beta-methylvaleric acid …
Matched Description: … It is important in hemoglobin synthesis and regulation of blood sugar and energy levels. ... It is an isomer of leucine. ... An essential branched-chain aliphatic amino acid found in many proteins. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... NUTRIPLUS LIPID SENZA ELETTROLITI …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It is important in hemoglobin synthesis and regulation of blood sugar and energy levels. ... It is an isomer of leucine. ... An essential branched-chain aliphatic amino acid found in many proteins. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... NUTRIPLUS LIPID SENZA ELETTROLITI …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Doxycycline
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Synonyms: … 6-alpha-deoxy-5-oxytetracycline …
Matched Description: … It is also used to treat acne and malaria.[A251730] ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections ... [L42880] It is a second-generation tetracycline that was first discovered in 1967. …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Vibramycin Inj …
Matched Description: … It is also used to treat acne and malaria.[A251730] ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections ... [L42880] It is a second-generation tetracycline that was first discovered in 1967. …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Vibramycin Inj …
Displaying drugs 1076 - 1100 of 1187 in total