Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 1076 - 1100 of 1355 in total
Trametes versicolor fruiting body is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Products: … SOMA Heart-Q …
CMC 001 is an orally administered MRI contrast agent in development for enhancement of the liver, bile ducts and gastrointestinal tract.
Investigational
Matched Description: … CMC 001 is an orally administered MRI contrast agent in development for enhancement of the liver, bile …
MB07133 is a HepDirect prodrug of an activated form of cytarabine (araC), an anti-cancer drug that is used to treat leukemia but is ineffective against primary liver cancer. AraC's anti-cancer activity is associated with its ability to be converted to its biologically active form, araCTP. However, araC is only slowly...
Investigational
Matched Description: … However, araC is only slowly converted to araCTP in the liver or in primary liver tumors due to low levels ... cytarabine (araC), an anti-cancer drug that is used to treat leukemia but is ineffective against primary liver ... MB07133 uses our HepDirect technology to target a prodrug form of araCMP specifically to the liver. …
Tezosentan is an intravenous endothelin receptor A/B antagonist. Tezosentan was initially developed for vasodilation in patients with acute heart failure but studies have shown that it does not assist in the treatment of dyspnea or prevent cardiovascular events.
Investigational
Matched Description: … Tezosentan was initially developed for vasodilation in patients with acute heart failure but studies …
PI-166 is a small organic compound with specific avidity to liver cancer cells. It has demonstrated the ability to reduce the growth of rat hepatomas, which is like human hepatomas, are resistant to established anti-cancer agents.
Investigational
Matched Description: … PI-166 is a small organic compound with specific avidity to liver cancer cells. …
Darusentan is a selective endothelin ETA receptor antagonist. It is being evaluated as a treatment for congestive heart failure and hypertension.
Investigational
Matched Description: … It is being evaluated as a treatment for congestive heart failure and hypertension. …
MB07811 is the first of a novel class of product candidates discovered by Metabasis designed to lower serum cholesterol and triglycerides. MB07811, a small molecule that is administered orally, has been extensively studied preclinically and is currently undergoing clinical testing. MB07811 combines a novel thyroid hormone receptor agonist with the...
Investigational
Matched Description: … The combination of selectivity for the beta form of the receptor, liver targeting and other structural ... MB07811 combines a novel thyroid hormone receptor agonist with the Company's novel HepDirect liver targeting ... efficacy while avoiding side effects associated with activation of thyroid hormone receptors outside the liver
Emricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA. It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis.
Investigational
Matched Description: … It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis …
Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and congestive heart failure.
Investigational
Matched Description: … converting enzyme inhibitor under development for the treatment of essential hypertension and congestive heart
DG031, deCODE genetics's lead compound, is being developed for the prevention of myocardial infarction, or heart attack.
Investigational
Matched Description: … deCODE genetics's lead compound, is being developed for the prevention of myocardial infarction, or heart
Pradefovir mesilate (previously known as MB-06886, Hepavir B and remofovir mesylate) is an orally administered small molecule compound that belongs to a novel series of phosphate and phosphonate prodrugs of adefovir. Adefovir (Hepsera) is an acyclic phosphonate analogue of adenine that is used to treat hepatitis B virus. As adefovir...
Investigational
Matched Description: … associated with a high level of nephrotoxicity, pradefovir mesilate was designed to specifically target the liver ... through oxidation that is mediated by cytochrome P-450 (CYP) 3A4, which is predominantly expressed in the liver
Ginseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties. Ginseng is also known to contain phytoestrogens.
Investigational
Nutraceutical
Matched Products: … Liver Care Honzo Seika Chinese Herbal Aroma Oil …
Alferminogene tadenovec, Cardium’s lead product candidate, is being developed for the potential treatment of myocardial ischemia that gives rise to angina symptoms associated with coronary heart disease. Alferminogene tadenovec represents a new therapeutic class of biologics designed to promote angiogenesis and thereby improve blood flow following a one-time intracoronary administration...
Investigational
Matched Description: … potential treatment of myocardial ischemia that gives rise to angina symptoms associated with coronary heart
Eprotirome which is a compound with promising properties for treatment of obesity and dyslipidemia. Eprotirome increases the body’s energy consumption and reduces body weight and markedly reduces blood lipids and blood glucose.
Investigational
Dilmapimod has been used in trials studying the treatment and diagnostic of Nerve Trauma, Inflammation, Pain, Neuropathic, Arthritis, Rheumatoid, and Coronary Heart Disease, among others. Dilmapimod (SB-681323) is a p38 MAP-kinase inhibitor that has potential uses in inflammatory conditions such as RA (Rheumatoid Arthritis). Previous p38 MAP-kinase inhibitors have been...
Investigational
Matched Description: … and diagnostic of Nerve Trauma, Inflammation, Pain, Neuropathic, Arthritis, Rheumatoid, and Coronary Heart ... Methotrexate (common treatment for RA patients) also has potential liver toxicity.} ... Previous p38 MAP-kinase inhibitors have been hindered in development by liver toxicity. …
Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
Experimental
Matched Description: … , liver, and kidney disease. ... as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart
Temocapril is a prodrug-type angiotensin-I converting enzyme (ACE) inhibitor not approved for use in the United States, but is approved in Japan and South Korea. Temocapril can also be used in hemodialysis patients without risk of serious accumulation.
Experimental
Investigational
Efonidipine is a calcium channel blocker of the dihydropyridine class, commercialized by Shionogi & Co. (Japan). Initially, it was marketed in 1995 under the trade name, Landel. The drug has been shown to block T-type in addition to L-type calcium channels [A7844, A32001]. It has also been studied in atherosclerosis...
Experimental
DG051 is a novel small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H), the protein made by one of the genes in the leukotriene pathway that has been shown to link to risk of heart attack. DG051 is designed to decrease risk of heart attack by decreasing the production of leukotriene B4...
Investigational
Matched Description: … protein made by one of the genes in the leukotriene pathway that has been shown to link to risk of heart ... DG051 is designed to decrease risk of heart attack by decreasing the production of leukotriene B4 (LTB4 …
Investigational
Sulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans .
Experimental
Matched Description: … Sulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans …
Matched Categories: … Tests for Liver Functional Capacity …
AVI-4557 is an oral antisense compound that selectively inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a liver enzyme responsible for the metabolism or breakdown of approximately half of currently marketed drugs. Studies indicate that AVI-4557 can successfully reduce the rate of metabolism for certain drugs, therefore allowing greater and...
Investigational
Matched Description: … oral antisense compound that selectively inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a liver
Experimental
Matched Categories: … Liver Therapy ... Bile and Liver Therapy ... Liver Therapy, Lipotropics …
Taurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile. As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile...
Experimental
Matched Description: … Taurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. ... As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely ... used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to …
A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and...
Experimental
Illicit
Matched Description: … It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function …
Displaying drugs 1076 - 1100 of 1355 in total