Displaying drugs 1601 - 1625 of 2395 in total
Bupivacaine
Bupivacaine is a widely used local anesthetic agent.
Approved
Investigational
Matched Mixtures name: … Sensorcaine Forte ... Bupivacaine Hci and Epinephrine ... Bupivacaine Hydrochloride and Epinephrine …
Matched Categories: … bupivacaine and meloxicam …
Matched Products: … Regivell Heavy 0.5% Solution for Injection ... Bupicaine D 0.5% w/v Solution for Injection ... BUPIVACAINE-BAXTER SOLUTION FOR INJECTION 5 MG/ML …
Matched Categories: … bupivacaine and meloxicam …
Matched Products: … Regivell Heavy 0.5% Solution for Injection ... Bupicaine D 0.5% w/v Solution for Injection ... BUPIVACAINE-BAXTER SOLUTION FOR INJECTION 5 MG/ML …
Dupilumab
Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … immunological reactions in several atopic or allergic conditions, such as eczema, allergic reaction, and ... inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and ... dermatitis, asthma as an add-on maintenance treatment, chronic rhinosinusitis with nasal polyposis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Agents for Dermatitis, Excluding Corticosteroids ... Skin and Mucous Membrane Agents …
Matched Products: … Dupixent 300 mg Solution for Injection in Pre-filled Syringe ... Dupixent 200mg Solution for Injection in Pre-Filled Syringe ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Agents for Dermatitis, Excluding Corticosteroids ... Skin and Mucous Membrane Agents …
Matched Products: … Dupixent 300 mg Solution for Injection in Pre-filled Syringe ... Dupixent 200mg Solution for Injection in Pre-Filled Syringe ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml …
Amphotericin B
Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While...
Approved
Investigational
Matched Description: … The antibiotic is without effect on bacteria, rickettsiae, and viruses. ... Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. ... Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antimycotics for Systemic Use …
Matched Products: … AMPHOTRET FOR INJECTION USP 50MG ... Amphotericin B for Injection, USP ... AMBISOME FOR INJECTION 50 mg/vial …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antimycotics for Systemic Use …
Matched Products: … AMPHOTRET FOR INJECTION USP 50MG ... Amphotericin B for Injection, USP ... AMBISOME FOR INJECTION 50 mg/vial …
D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamide
Experimental
Matched Name: … D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamide …
Matched Iupac: … {amino[4-({[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}methyl)phenyl]methylidene …
Matched Iupac: … {amino[4-({[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}methyl)phenyl]methylidene …
1-{[N-(1-Imino-guanidino-methyl)]sulfanylmethyl}-3-trifluoromethyl-benzene
Experimental
Matched Name: … 1-{[N-(1-Imino-guanidino-methyl)]sulfanylmethyl}-3-trifluoromethyl-benzene …
Matched Iupac: … N-[({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)methanimidoyl]guanidine …
Matched Iupac: … N-[({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)methanimidoyl]guanidine …
4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE
Experimental
Matched Name: … 4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE …
Matched Iupac: … 4-[(5-benzenesulfonamido-1-methyl-1H-1,3-benzodiazol-2-yl)methyl]benzene-1-carboximidamide …
Matched Iupac: … 4-[(5-benzenesulfonamido-1-methyl-1H-1,3-benzodiazol-2-yl)methyl]benzene-1-carboximidamide …
N-[(1S)-2-methyl-1-(pyridin-4-ylcarbamoyl)propyl]cyclohexanecarboxamide
Experimental
Matched Name: … N-[(1S)-2-methyl-1-(pyridin-4-ylcarbamoyl)propyl]cyclohexanecarboxamide …
Matched Iupac: … (2S)-2-(cyclohexylformamido)-3-methyl-N-(pyridin-4-yl)butanamide …
Matched Iupac: … (2S)-2-(cyclohexylformamido)-3-methyl-N-(pyridin-4-yl)butanamide …
5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine
Experimental
Matched Name: … 5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-8-ethenyl-9H-purin-9-yl)-5-({[4-(aminooxy)butyl](methyl)amino}methyl)oxolane …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-8-ethenyl-9H-purin-9-yl)-5-({[4-(aminooxy)butyl](methyl)amino}methyl)oxolane …
Technetium Tc-99m albumin colloid
Approved
Experimental
Matched Products: … Pulmolite, Kit for the Preparation of Technetium Tc99m Albumin Aggregated …
Trabectedin
Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate Ecteinascidia turbinata and now produced synthetically. Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair...
Approved
Investigational
Matched Description: … It is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma ... and ovarian cancer. ... and DNA repair machinery. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … YONDELIS 1MG FOR INJECTION ... YONDELIS Powder for Injection 1mg/vial …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … YONDELIS 1MG FOR INJECTION ... YONDELIS Powder for Injection 1mg/vial …
Entinostat
Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic Therapy.
Investigational
Matched Synonyms: … N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester …
Matched Iupac: … (pyridin-3-yl)methyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate …
Matched Description: … Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers ... , and Normal Volunteers. ... Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic Therapy. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … (pyridin-3-yl)methyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate …
Matched Description: … Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers ... , and Normal Volunteers. ... Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic Therapy. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Linagliptin
Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding . Linagliptin was approved by...
Approved
Matched Synonyms: … (R)-8-(3-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methylquinazolin-2-ylmethyl)-3,7-dihydro-purine …
Matched Iupac: … 8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,3,6,7 …
Matched Description: … that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and ... Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and linagliptin ... linagliptin and empagliflozin ... metformin, linagliptin and empagliflozin ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … 8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,3,6,7 …
Matched Description: … that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and ... Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and linagliptin ... linagliptin and empagliflozin ... metformin, linagliptin and empagliflozin ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Human cytomegalovirus immune globulin
Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label].
Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to infections which are followed by life-long...
Approved
Matched Description: … antibody for cytomegalovirus (CMV). ... Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of ... CMV infection can lead to a high fever and severe organ-specific damage with significant morbidity and …
Matched Categories: … Antiinfectives for Systemic Use ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … MEGALOTECT CP SOLUTION FOR INFUSION 100 U/ML …
Matched Categories: … Antiinfectives for Systemic Use ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … MEGALOTECT CP SOLUTION FOR INFUSION 100 U/ML …
Pyrophosphoric acid
Approved
Experimental
Matched Products: … TECHNESCAN PYP, KIT FOR RADIOPHARMACEUTICAL PREPARATION, 20MG/VIAL …
Cangrelor
Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion...
Approved
Matched Synonyms: … 3,3,3-trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl …
Matched Iupac: … trifluoropropyl)sulfanyl]-9H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl})methyl …
Matched Description: … ) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset and ... An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel ... Cangrelor was approved by the FDA in June 2015 for intravenous application. …
Matched Categories: … Blood and Blood Forming Organs ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … trifluoropropyl)sulfanyl]-9H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl})methyl …
Matched Description: … ) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset and ... An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel ... Cangrelor was approved by the FDA in June 2015 for intravenous application. …
Matched Categories: … Blood and Blood Forming Organs ... Nucleic Acids, Nucleotides, and Nucleosides …
AB-8939
Investigational
Matched Synonyms: … 1-(4-(2-(5-ethoxymethyl-2-methyl-phenylamino)-oxazol-5-yl)-phenyl)-imidazolidin-2-one …
Valaciclovir
Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Synonyms: … L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine …
Matched Description: … This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900 ... treat various herpes infections for more than 2 decades. ... Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Acyclovir and prodrug ... Amino Acids, Peptides, and Proteins …
Matched Description: … This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900 ... treat various herpes infections for more than 2 decades. ... Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Acyclovir and prodrug ... Amino Acids, Peptides, and Proteins …
Cinacalcet
Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Approved
Matched Synonyms: … (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine …
Matched Description: … and as Mimpara® in Europe. ... Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia …
Matched Categories: … Sex Hormones and Insulins ... Calcium-Regulating Hormones and Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … and as Mimpara® in Europe. ... Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia …
Matched Categories: … Sex Hormones and Insulins ... Calcium-Regulating Hormones and Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Pioglitazone
Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.[L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert in vivo with little consequence. The thiazolidinedione class...
Approved
Investigational
Matched Synonyms: … (±)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione …
Matched Iupac: … 5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione …
Matched Description: … safer and more effective alternatives for patients with type 2 diabetes mellitus. ... affect numerous metabolic processes, most notably lipid and glucose homeostasis. ... Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications …
Matched Mixtures name: … Pioglitazone and metformin ... Pioglitazone and Glimepiride ... Pioglitazone and Glimepiride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and pioglitazone ... pioglitazone and alogliptin ... glimepiride and pioglitazone ... pioglitazone and sitagliptin …
Matched Iupac: … 5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione …
Matched Description: … safer and more effective alternatives for patients with type 2 diabetes mellitus. ... affect numerous metabolic processes, most notably lipid and glucose homeostasis. ... Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications …
Matched Mixtures name: … Pioglitazone and metformin ... Pioglitazone and Glimepiride ... Pioglitazone and Glimepiride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and pioglitazone ... pioglitazone and alogliptin ... glimepiride and pioglitazone ... pioglitazone and sitagliptin …
Coffee bean
Coffee bean allergenic extract is used in allergenic testing.
Approved
Matched Products: … Coffee for Diagnostic Use Only …
Anthrax vaccine
Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to Bacillus anthracis. It is subcutaneously or intramuscularly administered. It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis...
Approved
Matched Description: … [L47561]
There are currently 2 anthrax vaccines approved by the FDA: BioThrax in August 15, 2016 and ... Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high ... an Anthrax terrorist attack or for pre-exposure prophylaxis of personnel going to specific arenas around …
Matched Products: … BioThrax (Anthrax Vaccine Adsorbed) Supension for Injection 50?g/dose (nominal) …
Matched Products: … BioThrax (Anthrax Vaccine Adsorbed) Supension for Injection 50?g/dose (nominal) …
Fomepizole
Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Approved
Vet approved
Matched Iupac: … 4-methyl-1H-pyrazole …
Matched Description: … alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and …
Matched Products: … Fomepizole for Injection …
Matched Description: … alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and …
Matched Products: … Fomepizole for Injection …
Chlorzoxazone
A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched International brands: … Strifon Forte DSC …
Matched Description: … is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and …
Matched Mixtures name: … Extra Strength Tylenol Aches and Strains ... Parafon Forte ... Acetazone Forte …
Matched Categories: … Benzoxazoles and derivatives ... Oxazol, Thiazine, and Triazine Derivatives …
Matched Products: … Parafon Forte ... Parafon Forte DSC ... PARAFLEX FORTE TABLET 500 MG, 20 ADET …
Matched Description: … is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and …
Matched Mixtures name: … Extra Strength Tylenol Aches and Strains ... Parafon Forte ... Acetazone Forte …
Matched Categories: … Benzoxazoles and derivatives ... Oxazol, Thiazine, and Triazine Derivatives …
Matched Products: … Parafon Forte ... Parafon Forte DSC ... PARAFLEX FORTE TABLET 500 MG, 20 ADET …
Fremanezumab
Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for the prevention of migraine headaches. It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. Along with other recently approved anti-CGRP therapies such as galcanezumab, erenumab, and the oral CGRP antagonist...
Approved
Investigational
Matched Description: … Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for ... [L11749] It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. ... [L11779] Along with other recently approved anti-CGRP therapies such as [galcanezumab], [erenumab], and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5ML …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5ML …
Methylnaltrexone
Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Matched Iupac: … (1S,4R,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-4-methyl-14-oxo-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸ …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Constipation …
Matched Products: … Relistor Solution For Injection 12mg/0.6mL …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Constipation …
Matched Products: … Relistor Solution For Injection 12mg/0.6mL …
Displaying drugs 1601 - 1625 of 2395 in total