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Displaying drugs 226 - 250 of 12187 in total
An antibiotic derived from penicillin similar to carbenicillin in action.
Approved
Investigational
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 ... ]heptane-2-carboxylic acid …
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-carboxy-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 ... ]heptane-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ebola virus (EBOV) remains an important human pathogen within the Ebolavirus genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%. Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid...
Approved
Matched Description: … [A222078] The chief surface target of EBOV particles is the GP1,2 glycoprotein, which also ... All three mAbs bind to a distinct portion of the GP1,2 glycoprotein and collectively provide …
Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. It is a semisynthetic analog of the doxorubicin, which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.
Approved
Matched Synonyms: … (8S, 10S)-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido ... 2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino] ... hexopyranosyl}oxy)-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethyl pentanoate …
Matched Iupac: … -2-yl]oxy}-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethyl pentanoate ... 2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-4-{[(2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)oxan …
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Synonyms: … (+)-cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H) ... (2S-cis)-3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin- ... (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin …
Matched Iupac: … (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3- …
Matched Salts cas: … 144604-00-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … KAFİZEM %2 KREM , 30 G ... Diltiarec %2 Krem, 30 G ... LOCAFEN % 2 KREM, 30 GRAM …
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … [3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane ... -2-carboxylic acid …
Matched Salts cas: … 1173-88-2 ... 7240-38-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … OXACILINA 1 G ... OXACILINA 1 G POLVO ESTERIL PARA SOLUCION INYECTABLE. ... OXACILINA 1 G POLVO ESTÉRIL PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),4,10,12-pentaen-8-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ZADITEN SRO FILM TABLET 2 MG, 30 ADET ... KETOTIFENO 1 MG ... KETEN TABLET 1 mg …
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Synonyms: … (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine ... (-)-2'-Deoxy-3'-thiacytidine ... 2',3'-Dideoxy-3'-thiacytidine …
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). …
Matched Mixtures name: … TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Synonyms: … 4-chloro-1-hydroxy-3,5-dimethylbenzene ... 2-Chloro-m-xylenol ... 2-chloro-5-hydroxy-m-xylene …
Matched Mixtures name: … Multi-action Denorex 2-IN-1 Dandruff Shampoo + Conditioner …
Matched Products: … Ak-1 1% ... Pro Care Spectracare Liq 1% ... Derma 1 Healthcare Hand Wash …
Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Synonyms: … (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol …
Matched Description: … to be approved. indicated for managing diabetes mellitus type 2. ... Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor ... was originally approved by the FDA on Jan 08, 2014, to improve glycemic control in adults with type 2
Matched Salts cas: … 960404-48-2
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Matched Products: … DAPAGLEZE 10 MG FILM KAPLI TABLET, 90 ADET ... DAPAGLEZE 5 MG FILM KAPLI TABLET, 90 ADET ... CALİRA 10 MG FİLM KAPLI TABLET, 90 ADET …
Approved
Investigational
Matched Synonyms: … Pregna-1,4-diene-3,20-dione, 21-((cyclopropylcarbonyl)oxy)-6,9-difluoro-11-hydroxy-16,17-((1-methylethylidene …
Matched Iupac: … [10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-8-yl]-2-oxoethyl cyclopropanecarboxylate ... 2-[(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo …
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Synonyms: … 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine …
Matched Description: … Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase ... Etoricoxib is a new COX-2 selective inhibitor. ... enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Products: … ETROBAX 90 FILM COATED TABLETS 90 MG ... LACOSIB 90 ... COXIRON 90
Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic...
Approved
Vet approved
Withdrawn
Matched Synonyms: … N(1)-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide …
Matched Iupac: … 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide …
A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Approved
Matched Synonyms: … 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one ... 8-methoxy-2',3',6,7-furocoumarin ... 8-methoxy-[furano-3'.2':6.7-coumarin] …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Ultra Mop Lotion 1% ... VİTPSO %1 JEL 50 GR …
Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). It has been proposed that by interacting with the ETC, idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and...
Approved
Investigational
Matched Synonyms: … 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone ... 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone ... 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione …
Matched Iupac: … 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione …
Matched Mixtures name: … EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLET ... EVERON 90/5 MG FILM KAPLI TABLET ,100 TABLET ... SALPEZIL 90/10 MG FILM KAPLI TABLET ,TABLET, 28 ADET …
Matched Products: … IDEBEX 90 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET ... IDEBEX 45 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET ... IDEBEX 90 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 30 ADET …
Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.[A180163,L7084,L7087,L7090,L7093] Tiotropium is more specific for the subset of muscarinic receptors commonly found in the...
Approved
Matched Iupac: … (1R,2R,4S,5S,7R)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0 …
Matched Mixtures name: … SPIOLTO RESPIMAT 2.5 MCG/2.5 MCG INHALASYON ÇÖZELTISI,1 ADET ... ROPITAL 18/2 MCG INHALASYON IÇIN TOZ IÇEREN BLISTER , 60 DOZ ... ROPITAL 18/2 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL,60 KAPSÜL …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … SPIRIVA RESPIMAT 2.5 MCG/PUSKURTME INHALASYON COZELTISI 1 KARTUS ... BRONTİO 18 MCG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 90 ADET ... DAYTIO 18 MCG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 90 ADET …
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Synonyms: … 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one ... one4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one ... (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one …
Matched Iupac: … (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one …
Matched Description: … active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 1-Ring ... Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor …
Roflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor. PDE4 is a major cyclic-3',5′-adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells like those of the smooth muscle or epithelium. The resultant increase in intracellular cAMP induced by roflumilast's inhibition of PDE4...
Approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ROFLUNG 0,5 MG SAŞE ,90 SAŞE ... BROLUST 500 MCG TABLET, 90 TABLET ... DAXAS 500 MCG FILM TABLET, 90 ADET …
Approved
Matched Products: … MON.LUTEC 37 GBQ/ML RADYOFARMASÖTİK PREKÜRSÖR, ÇÖZELTİ, 1 ADET ... LUMARK 80 GBq/ML RADYOFARMASÖTİK PREKÜRSÖR, ÇÖZELTİ, 1 ADET …
Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs). This drug is prescribed in combination with other drugs for the management of HIV infection as well as for...
Approved
Investigational
Matched Iupac: … bis({[(propan-2-yloxy)carbonyl]oxy}methyl) {[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methanephosphonate …
Matched Salts cas: … 1453166-76-1
Matched Mixtures name: … STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 90 ADET …
Matched Products: … VIRSOEM 245 MG FILM TABLET, 90 ADET ... ZENTOVIR 245 MG FILM TABLET, 90 ADET ... DORO 245 MG FILM KAPLI TABLET, 90 ADET …
Colesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bile acids in the intestine. Bile acids are made when cholesterol is broken...
Approved
Matched Products: … COSELAM 1875 MG SAŞE, 90 SAŞE ... COSELAM 3750 MG SAŞE, 90 SAŞE ... KOVEL 625 MG FİLM KAPLI TABLET, 90 ADET …
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Synonyms: … (1-Amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide ... 3-(((2-((Diaminomethylene)amino)-4-thiazolyl)methyl)thio)-N(sup 2)-sulfamoylpropionamidine ... N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide …
Matched Iupac: … 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide …
Matched Description: … Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric ... [L11166] Compared to other H2 receptor antagonists, famotidine displays high selectivity towards …
Matched Mixtures name: … ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 2 ADET …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Zantac 360 1 per blister 6 blisters ... FABOS 20 MG/2 ML ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 2 ADET ... 2 ADET ÇÖZÜCÜ AMPUL …
Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of...
Approved
Illicit
Matched Salts cas: … 5965-15-1
Matched Products: … Codidol retard 90 mg - Filmtabletten ... Dehace retard 90 mg - Filmtabletten …
Hydroxycitronellal is a synthetic fragrance that is widely used in many cosmetics and hygiene products such as deodorants, soaps, antiseptics, and other household items. It has the smell of lilac, lily, and lily of the valley . Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and...
Approved
Experimental
Matched Synonyms: … 3,7-dimethyl-7-hydroxyoctan-1-al …
Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Iupac: … 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … ARİPA 2 MG TABLET, 2 ADET ... ARİPA 2 MG TABLET, 7 ADET ... ARİPA 2 MG TABLET, 28 ADET …
Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary...
Approved
Matched Synonyms: … endo-8,8-Dimethyl-3-((1-oxo-2-propylpentyl)oxy)-8-azoniabicyclo(3.2.1)octane bromide ... 8-Methyltropinium bromide 2-propylvalerate ... 8-Methyltropinium bromide 2-propylpentanoate …
Matched Iupac: … 8,8-dimethyl-3-[(2-propylpentanoyl)oxy]-8-azabicyclo[3.2.1]octan-8-ium bromide …
Displaying drugs 226 - 250 of 12187 in total