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Displaying drugs 2476 - 2500 of 15224 in total
Poractant alfa
Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. It is used to treat Respiratory Distress Syndrome (RDS) in premature infants with an endogenous pulmonary surfactant deficiency. Poractant alfa is an extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids)...
Approved
Matched Description: … Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. ... 1% hydrophobic low molecular weight proteins (surfactant associated proteins SP-B and SP-C). ... an extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids) and …
Aluminum oxide
Aluminum oxide has a chemical formula Al2O3. It is amphoteric in nature, and is used in various chemical, industrial and commercial applications. It is considered an indirect additive used in food contact substances by the FDA.
Approved
Matched Description: … It is amphoteric in nature, and is used in various chemical, industrial and commercial applications. …
Cat dander extract
Cat dander extract is either subcutaneously or intracutaneously administered and contains dry cat dander or dry defatted cat pelt. It is used in the diagnosis and treatment (immunotherapy) of patients with a history of allergy to cats. An allergic reaction to cats is induced by the presence of antigen-specific IgE...
Approved
Matched Description: … Cat dander extract is either subcutaneously or intracutaneously administered and contains dry cat dander ... It is used in the diagnosis and treatment (immunotherapy) of patients with a history of allergy to cats ... The allergy diagnostic process involves assessing allergy history, clinical evaluation, and skin test …
Tripelennamine
A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.
Approved
Vet approved
Matched Description: … It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. …
Tizanidine
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an...
Approved
Investigational
Matched Description: … Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition. …
Pipotiazine
Pipotiazine has actions similar to those of other phenothiazines. Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics. However, it produces a high incidence of extra pyramidal reactions. It is...
Approved
Investigational
Matched Description: … for causing hypotension or potentiating the effects of CNS depressants and anesthetics. ... Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity ... Symptoms of overdose include severe extrapyramidal manifestations, hypotension, lethargy and sedation …
Lutetium Lu-177 vipivotide tetraxetan
Lutetium Lu-177 vipivotide tetraxetan is a radioligand therapeutic agent. It consists of a radionuclide, lutetium Lu-177, linked to a moiety that binds to PSMA, a transmembrane protein that is expressed in prostate cancer. Lutetium Lu-177 vipivotide tetraxetan was first approved by the FDA on March 23, 2022 as a treatment...
Approved
Nitrous oxide
Nitrous oxide, commonly known as "laughing gas", is a chemical compound with the chemical formula N2O. At room temperature, it is a colorless non-flammable gas, with a pleasant, slightly sweet odor and taste. It is used in surgery and dentistry for its anesthetic and analgesic effects. It is known as...
Approved
Vet approved
Matched Description: … It is used in surgery and dentistry for its anesthetic and analgesic effects. ... At room temperature, it is a colorless non-flammable gas, with a pleasant, slightly sweet odor and taste …
Tacrine
A centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. Tacrine has been discontinued for the United States market.
Approved
Investigational
Withdrawn
Matched Description: … in the treatment of Alzheimer's disease and other central nervous system disorders. ... inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and …
Repotrectinib
Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...
Approved
Investigational
Matched Description: … [A262056] ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ... compact macrocyclic structure that both limits adverse interactions with resistance mutation hotspots and ... resistance to multiple TKI has been reported, including [crizotinib], [lorlatinib], [taletrectinib], and …
Etafedrine
Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin and Dalmacol . It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued .
Ethylephedrine is...
Approved
Matched Description: … with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis …
Temoporfin
Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and neck [FDA Label]. It was first authorized for market by the European Medicines Agency in October 2001. It is currently available under the brand name Foscan.
Approved
Investigational
Matched Description: … Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Isoxsuprine
A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
Approved
Withdrawn
Matched Description: … It is used in the treatment of peripheral vascular disease and in premature labor. ... A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. …
Favipiravir
Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza.[A191688,A191721] The antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and replication of viral genomes.[A191688,A191772,A191775]
Not only does favipiravir inhibit...
Approved
Investigational
Matched Description: … [A191688,A191772,A191775]
Not only does favipiravir inhibit replication of influenza A and B, but ... the drug has shown promise in the treatment of avian influenza, and may be an alternative option for ... antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and …
Benziodarone
Benziodarone is a uricostatic and a uricosuric agent which is sold also under the name Amplivex-Labaz. It is used in the treatment of gout . It was withdrawn from France markets and British markets due to its effects causing Jaundice in patients [T487, A175636].
Approved
Withdrawn
Matched Description: … Benziodarone is a uricostatic and a uricosuric agent which is sold also under the name Amplivex-Labaz ... It was withdrawn from France markets and British markets due to its effects causing Jaundice in patients …
Cefamandole nafate
Approved
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Amitriptylinoxide
Amitriptylinoxide has been used in trials studying Major Depression.
Approved
Investigational
Methoxamine
An alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system.
Approved
Investigational
Matched Categories: … Adrenergic and Dopaminergic Agents …
Fenoldopam
A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Approved
Matched Categories: … Adrenergic and Dopaminergic Agents …
Pirbuterol
Pirbuterol is a beta-2 adrenergic bronchodilator. In vitro studies and in vivo pharmacologic studies have demonstrated that pirbuterol has a preferential effect on beta-2 Adrenergic receptors compared with isoproterenol. While it is recognized that beta-2 adrenergic receptors are the predominant receptors in bronchial smooth muscle, data indicate that there is...
Approved
Matched Description: … In vitro studies and in vivo pharmacologic studies have demonstrated that pirbuterol has a preferential ... Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release …
Tenapanor
Tenapanor is a novel, small molecule medication approved in September 2019 for the treatment of constipation-predominant irritable bowel-syndrome (IBS-C). It was first designed and synthesized in 2012. As an inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3) transporter, it is the first and currently only medication within its class[A185489,A185492,A185495] and...
Approved
Investigational
Matched Description: … [L8558] It was first designed and synthesized in 2012. ... currently only medication within its class[A185489,A185492,A185495] and therefore exists as a novel ... A185492] As an inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3) transporter, it is the first and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Categories: … Alimentary Tract and Metabolism …
Foreskin fibroblast (neonatal)
Foreskin fibroblast-like stromal cells (FDSCs) are progenitors isolated from human tissue that can differentiate into various cell types .
Also known as Dermagraft, this device is a cryopreserved human fibroblast-derived dermal substitute. Composed of fibroblasts, extracellular matrix, and a bioabsorbable scaffold, it effectively supports wound healing .
Dermagraft has only...
Approved
Matched Description: … , as well as New Zealand and Australia. ... The impact of diabetic foot ulcers (DFU) on individuals and society is devastating. ... Composed of fibroblasts, extracellular matrix, and a bioabsorbable scaffold, it effectively supports …
Yellow fever vaccine
Yellow fever vaccine prevents against Yellow Fever, a viral hemorrhagic disease caused by the transmission of a flavivirus through the bite of an infected mosquito. Symptoms of Yellow fever can range from asymptomatic, to mild flu-like illness, to more severe symptoms such as shock, jaundice, internal bleeding, and organ failure...
Approved
Investigational
Matched Description: … of yellow fever in pediatric patients 9 months of age and older. ... Interestingly, Yellow fever got its name from the characteristic yellowing of the skin and eyes that ... Vaccination with Yellow Fever vaccine is therefore considered to be the most important and effective …
Kinetin
Kinetin is a cytokinin which are plant hormones promotes cell division and plant growth. It was shown to naturally exist in DNA of organisms including humans and various plants. While kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an anti-aging...
Approved
Matched Description: … Kinetin is a cytokinin which are plant hormones promotes cell division and plant growth. ... It was shown to naturally exist in DNA of organisms including humans and various plants. …
Displaying drugs 2476 - 2500 of 15224 in total