Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 2526 - 2550 of 3255 in total
A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Synonyms: … 2-Methyl-alpha-propylaminopropionanilide ... alpha-n-Propylamino-2-methylpropionanilide ... o-Methyl-alpha-propylaminopropionanilide …
Matched Mixtures name: … Prilocaine Hydrochloride with Epinephrine ... Lidocaine and Prilocaine ... Lidocaine and Prilocaine …
Matched Salts name: … Prilocaine hydrochloride
Matched Products: … Prilocaine Hydrochloride ... Dentsply 4% Prilocaine Hydrochloride Dental Injection …
Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Salts name: … Nalmefene hydrochloride ... Nalmefene hydrochloride dihydrate …
Matched Products: … Nalmefene Hydrochloride
Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and
Matched Salts name: … Isoprenaline hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Products: … Isoproterenol Hydrochloride ... Isoproterenol hydrochloride ... Isoproterenol Hydrochloride Injection USP …
A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and
Matched Mixtures name: … Meperidine Hydrochloride and Promethazine Hydrochloride ... Meperidine Hcl and Promethazine Hcl …
Matched Salts name: … Meperidine hydrochloride
Matched Categories: … pethidine and antispasmodics ... Acids, Heterocyclic ... Isonipecotic Acids
Matched Products: … Meperidine Hydrochloride ... Meperidine Hydrochloride Injection USP ... DBL PETHIDINE HYDROCHLORIDE INJECTION BP 50mg/ml …
Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin-1-yl]- 2-oxo-ethyl]amino]acetate
Matched Iupac: … 2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin-1-yl]-2-oxoethyl]amino}acetate
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and
Matched Categories: … Blood and Blood Forming Organs …
Experimental
Matched Synonyms: … UDP-4-fluoro-4-deoxy-alpha-D-glucose …
Matched Name: … Uridine-5'-diphosphate-4-deoxy-4-fluoro-alpha-D-galactose …
Matched Iupac: … ,4R,5S,6R)-5-fluoro-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphinic acid
Approved
Investigational
Matched Synonyms: … alpha-Narcotine …
Matched Salts name: … Noscapine hydrochloride
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin and Dalmacol . It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued . Ethylephedrine is...
Approved
Matched Synonyms: … alpha-(1-(ethylmethylamino)ethyl)benzyl alcohol …
Matched Description: … It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. …
Matched Salts name: … Etafedrine hydrochloride
Pimasertib is under investigation in clinical trial NCT01378377 (Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus).
Investigational
Matched Synonyms: … N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide …
Matched Iupac: … N-[(2S)-2,3-dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]pyridine-4-carboxamide …
Matched Salts name: … Pimasertib hydrochloride
Matched Categories: … Acids, Heterocyclic ... Nicotinic Acids
Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Description: … [A178159] In the treatment of benign prostate hyperplasia, alpha-blockers such as [tamsulosin] and [terazosin ... Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase ... first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and
Matched Mixtures name: … Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% ... Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% / Tretinoin 0.025% …
Matched Categories: … 5-alpha Reductase Inhibitors ... Adrenergic alpha-Antagonists ... doxazosin and finasteride ... alfuzosin and finasteride ... Skin and Mucous Membrane Agents …
Matched Products: … FOLIX 1 MG TABLETAS …
Durlobactam is a diazabicyclooctane non-beta-lactam, beta-lactamase inhibitor. It is typically given in combination with sulbactam to protect it from degradation by certain serine-beta-lactamases. The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023. It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial...
Approved
Investigational
Matched Synonyms: … SULFURIC ACID, MONO((2S,5R)-2-(AMINOCARBONYL)-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL) ESTER …
Matched Iupac: … [(1R,2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl]oxidanesulfonic acid
Matched Description: … [L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023 ... [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial …
Matched Salts name: … Durlobactam sodium
Investigational
Matched Synonyms: … Propanoic acid, 2-(((2,4,5,7-tetranitro-9h-fluoren-9-ylidene)amino)oxy)-, (4s)-10-((dimethylamino)methyl …
Matched Salts name: … Lipotecan hydrochloride
A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medication is classified as a Schedule V under the Controlled Substances Act...
Approved
Illicit
Matched Synonyms: … 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl ester …
Matched Description: … Its unesterified metabolite difenoxin has similar properties and is used similarly. ... Administration (FDA) and the DEA in the United States when used in preparations. ... This medication is classified as a Schedule V under the Controlled Substances Act by the Food and Drug …
Matched Mixtures name: … Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Salts name: … Diphenoxylate hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Isonipecotic Acids
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Matched Synonyms: … 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
Matched Description: … those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and ... thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release …
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and
Matched Salts name: … Doxorubicin hydrochloride
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Doxorubicin Hydrochloride ... DOXOrubicin Hydrochloride ... Doxorubicin hydrochloride
Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched Description: … Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and ... piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. ... for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. …
Matched Salts name: … Hydroxyzine hydrochloride
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride
An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Approved
Matched Synonyms: … DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid …
Matched Description: … An ethanolamine derivative that is an adrenergic alpha agonist. …
Matched Salts name: … Midodrine hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Midodrine Hydrochloride ... Midodrine hydrochloride
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Synonyms: … Glucagon-like peptide II (2-glycine) (human) …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant ... Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Various Alimentary Tract and Metabolism Products …
Experimental
Matched Name: … 2-Amino-3-(5-Tert-Butyl-3-(Phosphonomethoxy)-4-Isoxazolyl)Propionic Acid
Matched Iupac: … (2S)-2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-1,2-oxazol-4-yl]propanoic acid
Experimental
Matched Name: … {[(2,2-Dihydroxy-Ethyl)-(2,3,4,5-Tetrahydroxy-6-Phosphonooxy-Hexyl)-Amino]-Methyl}-Phosphonic Acid
Matched Iupac: … 2R,3R,4R,5R)-6-[(2,2-dihydroxyethyl)(phosphonomethyl)amino]-2,3,4,5-tetrahydroxyhexyl]oxy}phosphonic acid
Experimental
Matched Name: … Sulfamic Acid 2,3-O-(1-Methylethylidene)-4,5-O-Sulfonyl-Beta-Fructopyranose Ester …
Experimental
Matched Name: … 6-(2-Oxo-Hexahydro-Thieno[3,4-D]Imidazol-4-Yl)-Hexanoic Acid
Matched Iupac: … 6-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]hexanoic acid
Experimental
Matched Name: … 5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid
Matched Iupac: … 5-{[(4-{[(2S)-1-carboxy-3-oxobutan-2-yl]carbamoyl}phenyl)methyl]sulfamoyl}-2-hydroxybenzoic acid
Experimental
Matched Name: … 1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester …
Experimental
Matched Name: … Morpholine-4-Carboxylic Acid (1-(3-Benzenesulfonyl-1-Phenethylallylcarbamoyl)-3-Methylbutyl)-Amide …
Displaying drugs 2526 - 2550 of 3255 in total