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Displaying drugs 2526 - 2550 of 6875 in total
Experimental
Matched Name: … [(2r,3s,4r,5r)-5-(6-Amino-9h-Purin-9-Yl)-3,4-Dihydroxytetrahydro-2-Furanyl]Methyl Sulfamate …
Matched Iupac: … [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl sulfamate …
Nemtabrutinib is under investigation in clinical trial NCT05624554 (A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008)).
Investigational
Matched Synonyms: … D-erythro-hexitol, 1,5-anhydro-2-((5-(2-chloro-4-phenoxybenzoyl)-7h-pyrrolo(2,3-d)pyrimidin-4-yl)amino ... 1,5-Anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy-D-erythro-hexitol ... -d)pyrimidin-5-yl)methanone …
NS3728 is an orally active chloride channel blocker for the treatment of cancer.
Investigational
Matched Synonyms: … N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-N'-[3,5-bis(trifluoromethyl)phenyl]urea …
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …
Tagatose is a functional sweetener. It is a naturally occurring monosaccharide, specifically a hexose. It is commonly found in dairy with a similar texture and sweetened capacity to sucrose but with only a third of the calories. It is approved as a food additive as a low calorie sweetener. Additionally,...
Investigational
Experimental
Matched Synonyms: … 5,5-Dimethyl-3-(2-((7-methyl-2H-spiro[benzofuran-3,1'-cyclopropan]-4-yl)oxy)pyrimidin-5-yl)imidazolidine ... 5,5-dimethyl-3-[2-(7-methylspiro[2H-benzofuran-3,1'-cyclopropane]-4-yl)oxypyrimidin-5-yl]imidazolidine …
MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor.
Investigational
Matched Description: … MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). …
Investigational
Matched Synonyms: … 2-((1s)-1-((6-amino-5-cyano-4-pyrimidinyl)amino)ethyl)-3,4-dihydro-4-oxo-3-phenylpyrrolo(2,1-f)(1,2,4 ... Pyrrolo(2,1-f)(1,2,4)triazine-5-carbonitrile, 2-((1s)-1-((6-amino-5-cyano-4-pyrimidinyl)amino)ethyl)- ... )triazine-5-carbonitrile …
Matched Iupac: … 4-amino-6-{[(1S)-1-{5-cyano-4-oxo-3-phenyl-3H,4H-pyrrolo[2,1-f][1,2,4]triazin-2-yl}ethyl]amino}pyrimidine ... -5-carbonitrile …
Experimental
Investigational
Matched Synonyms: … 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4 …
Matched Iupac: … 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H,3H,4H-pyrido[3,2- …
Experimental
Matched Name: … 3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE …
Investigational
Matched Synonyms: … 5-(3,5-Dimethyl-4-hydroxybenzylamino)-3-(4-morpholin-4-yl-phenylamino)-1H-pyrazole-4-carboxylic acid …
Matched Iupac: … 5-{[(4-hydroxy-3,5-dimethylphenyl)methyl]amino}-3-{[4-(morpholin-4-yl)phenyl]amino}-1H-pyrazole-4-carboxamide …
Experimental
Matched Name: … (5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-[[(S)-(4-fluorophenyl)-(2H-tetrazol-5-yl)methyl]amino]-1,3- ... thiazol-4-one …
Matched Iupac: … }-4,5-dihydro-1,3-thiazol-4-one ... (5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-{[(S)-(4-fluorophenyl)(1H-1,2,3,4-tetrazol-5-yl)methyl]amino …
Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer under most conditions. It helps its virus evade the host immune system through selectively blocking and activating different receptors, preferentially...
Investigational
Matched Description: … protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. …
Lesopitron is an anxiolytic with pre- and post-synaptic 5-HT1A agonist activity, which is under development by Esteve.
Investigational
Matched Synonyms: … 2-(4-(4-(4-Chloropyrazol-1-yl)butyl)-1-piperazinyl)pyrimidine …
Matched Iupac: … 2-{4-[4-(4-chloro-1H-pyrazol-1-yl)butyl]piperazin-1-yl}pyrimidine …
Matched Description: … Lesopitron is an anxiolytic with pre- and post-synaptic 5-HT1A agonist activity, which is under development …
Investigational
Quercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
Experimental
Investigational
Matched Synonyms: … 3,3',4',5,7-pentahydroxyflavone ... 3,5,7,3',4'-Pentahydroxyflavone ... FLAVONE, 3,3',4',5,7-PENTAHYDROXY- …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one …
Selonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis).
Investigational
Matched Synonyms: … 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin ... BENZAMIDE, 5-(4-CYCLOPROPYL-1H-IMIDAZOL-1-YL)-2-FLUORO-4-METHYL-N-(6-(4-(1-METHYLETHYL)-4H-1,2,4-TRIAZOL ... 5-(4-Cyclopropyl-1H-imidazol-l-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide …
Matched Iupac: … 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin …
BBV152 is a vaccine candidate created by the Indian Council of Medical Research (ICMR). The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV-2 strain and a vero cell platform (CCL-81) with adjuncts of either aluminum hydroxide gel (Algel) or a novel TLR7/8 agonist adsorbed gel....
Investigational
Matched Description: … vero cell platform (CCL-81) with adjuncts of either aluminum hydroxide gel (Algel) or a novel TLR7/8 ... The formulation with the TLR7/8 adjuvant specifically induced significant Th1 biased antibody responses …
Experimental
Matched Iupac: … {4-[(2S)-2-{[(3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-phosphonophenyl …
Experimental
Matched Iupac: … ({4-[(2S)-2-{[(3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]phenyl …
Experimental
Matched Name: … 7-methyl-7,8-dihydroguanosine-5'-diphosphate …
Matched Iupac: … [({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-2-imino-7-methyl-3,7,8,9-tetrahydro-2H-purin-9-yl)oxolan …
DSP-5336 is a menin inhibitor.
Investigational
Matched Synonyms: … BENZAMIDE, 5-FLUORO-2-((4-(7-(((1S,3S,4R)-5-METHYLENE-2-AZABICYCLO(2.2.2)OCT-3-YL)CARBONYL)-2,7-DIAZASPIRO ... (3.5)NON-2-YL)-5-PYRIMIDINYL)OXY)-N,N-BIS(1-METHYLETHYL)- …
Matched Iupac: … 5-fluoro-2-[(4-{7-[(1S,3S,4R)-5-methylidene-2-azabicyclo[2.2.2]octane-3-carbonyl]-2,7-diazaspiro[3.5] ... nonan-2-yl}pyrimidin-5-yl)oxy]-N,N-bis(propan-2-yl)benzamide …
Investigational
Matched Synonyms: … (1s,3r)-3-(acetylamino)-n-(5-chloro-4-(5,6-dihydro-5,5-dimethyl-4h-pyrrolo(1,2-b)pyrazol-3-yl)-2-pyridinyl …
Experimental
Matched Name: … 4-CHLORO-3',3''-DIBROMOPHENOL-1,8-NAPHTHALEIN …
Matched Iupac: … 4,4-bis(3-bromo-4-hydroxyphenyl)-10-chloro-3-oxatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaen …
Experimental
Matched Name: … 4-Hydroxy-3,5-Dimethyl-5-(2-Methyl-Buta-1,3-Dienyl)-5h-Thiophen-2-One …
Matched Iupac: … (5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1,3-dien-1-yl]-2,5-dihydrothiophen-2-one …
Experimental
Matched Synonyms: … 5-Amino-2,4-dihydroxypyrimidine ... 5-aminopyrimidine-2,4(1H,3H)-dione …
Matched Name: … 5-Aminouracil …
Matched Iupac: … 5-amino-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Displaying drugs 2526 - 2550 of 6875 in total