Displaying drugs 2701 - 2725 of 3217 in total
Daclizumab
Humanized IgG1 Mab that binds to the human interleukin-2 receptor (anti-Tac or anti-CD25). Daclizumab is a composite of human (90%) and murine (10%) antibody sequences. The human sequences were derived from the constant domains of human IgG1 and the variable framework regions of the Eu myeloma antibody. The murine sequences...
Investigational
Withdrawn
Matched Description: … Humanized IgG1 Mab that binds to the human interleukin-2 receptor (anti-Tac or anti-CD25). ... The murine sequences were derived from the complementarity-determining regions of a murine anti-Tac antibody …
Peoniflorin
Peoniflorin is under investigation in clinical trial NCT02878863 (Paeoniflorin Combination of Hepatoprotective Drugs Versus Hepatoprotective Drugs Only for Auto-immune Hepatitis).
Investigational
Matched Categories: … Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal …
Caryophyllene
Investigational
Matched Categories: … Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal …
Enrofloxacin
Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant strains of Campylobacter, in September 2005, the FDA withdrew the approval of enrofloxacin for its use in water to treat...
Vet approved
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Piromidic acid
Experimental
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Urinary …
Zotarolimus
Zotarolimus is an immunosuppressant under investigation for use in drug-eluting stents.
Investigational
Matched Categories: … Anti-Bacterial Agents …
Chlorproguanil
Chlorproguanil has been used in trials studying the treatment of MALARIA. It is a dichloro-derivative of chloroguanide.
Investigational
Matched Categories: … Anti-Infective Agents …
IQP-0528
IQP-0528 is under investigation in clinical trial NCT03082690 (ImQuest (IQP) DuoGel Phase 1 Pharmacokinetic Study).
Investigational
Matched Categories: … Anti-HIV Agents …
Flumequine
Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
Withdrawn
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... Anti-Infective Agents, Urinary …
Ebselen
Ebselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus.
Investigational
Matched Categories: … Anti-Ulcer Agents ... Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal …
1D09C3
1D09C3, a monoclonal antibody against lymphoid cancers, is an anti-MHC (major histocompatibility complex) class II monoclonal antibody. The antibody was isolated in collaboration with MorphoSys from its HuCAL(R) library of human antibodies. 1D09C3 binds to certain cell surface receptors, selectively killing activated, proliferating MHC class II-positive tumor cells, which include...
Investigational
Matched Description: … 1D09C3, a monoclonal antibody against lymphoid cancers, is an anti-MHC (major histocompatibility complex …
CR665
CR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid receptor agonists. In preclinical studies, CR665 was highly selective for the peripheral kappa opioid receptor. Preclinical animal studies suggest that CR665 is a potent analgesic compound. In addition, unlike currently marketed opioids, CR665 does...
Investigational
Matched Description: … Preclinical studies also indicate that CR665 possesses anti-inflammatory activities. …
AP5346
AP5346 is designed to target a diaminocyclohexane platinum (Pt) moiety to tumors through pH-sensitive linkage to a 25 kDa hydroxypropylmethacrylamide polymer. It is being pursued by Access Pharmaceuticals, Inc.
Investigational
Natural Killer Cell
Natural Killer (NK) cells originate and differentiate from hematopoietic stem cells through various signalling pathways involving cytokines and interleukins. These cells arise from CD34+ lymphoid progenitors and comprise 10-15% of all lymphocytes in human peripheral blood. Once completely differentiated, NK cells lack B (CD19-) and T(CD3-) lymphocyte markers and carry...
Investigational
Formebolone
Formebolone, a derivative of androstane, is an anabolic androgenic steroid. It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened for in athletes. It is also classified by the US Drug Enforcement Administration as Schedule III drug in the Controlled Substances Act. It...
Experimental
Illicit
Matched Description: … It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened …
AT9283
AT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer. It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.
Investigational
Interferon Kappa
Interferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino acids and has 30% homology with others of the same class as it consists of a series of cysteine and a 27-amino acid signal peptide conserved in type I interferons. This gene encoding...
Investigational
MRx-4DP0004
MRx-4DP0004 is a lyophilised formulation of the Bifidobacterium breve strain of commensal bacteria. It is a live biotherapeutic derived from the microbiota of a healthy human infant.
Investigational
Cefminox
Cefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan.
Experimental
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Nigericin
A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)
Experimental
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Displaying drugs 2701 - 2725 of 3217 in total