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Displaying drugs 251 - 275 of 8783 in total

Alefacept

Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. Produced by CHO cells, mW is 91.4 kD.
Approved
Investigational
Withdrawn
Matched Description: … (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. ... protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 …
Matched Categories: … CD2-directed LFA-3/Fc Fusion Protein …

Leniolisib

Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). The FDA approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3-kinase delta syndrome (APDS). APDS is a primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby increasing the activity of...
Approved
Investigational
Matched Iupac: … 1-[(3S)-3-({6-[6-methoxy-5-(trifluoromethyl)pyridin-3-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-yl}amino …
Matched Description: … Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). ... approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3- …

Bismuth subsalicylate

Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Description: … Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. …

Bacillus calmette-guerin substrain russian BCG-I live antigen

Bacillus Calmette-Guerin (BCG) substrain Russian BCG-I is a live BCG vaccine administered directly into the bladder for the adjuvant treatment of papillary urothelial cell carcinoma of the bladder. Live BCG vaccines administered intravesically have been a gold standard therapy in the adjuvant treatment of non-muscle-invasive bladder cancers for decades, used...
Approved

Teplizumab

Teplizumab (teplizumab-mzwv) is a humanized IgG1 kappa CD3-directed monoclonal antibody used to delay the onset of type 1 diabetes (T1D).[A241480,A241045,A241475,L44091] T1D is an autoimmune condition in which T cell-mediated destruction of pancreatic β cells leads to loss of insulin production, impaired glycemic control, and reliance on exogenous insulin. Anti-CD3 therapy...
Approved
Investigational

Cabozantinib

Cabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. It was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer. In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal...
Approved
Investigational
Matched Salts cas: … 1140909-48-3 …

Icosapent

Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Approved
Nutraceutical
Matched Description: … It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. …
Matched Mixtures name: … Animi-3 ... BP Vit 3 ... Super Omega 3 …
Matched Categories: … Fatty Acids, Omega-3 …

Relatlimab

Relatlimab is a human IgG4 monoclonal antibody and novel immune checkpoint inhibitor that targets lymphocyte activation gene-3 (LAG-3).[A246165,L41265] It was the first commercially developed anti-LAG-3 antibody, entering clinical trials in 2013, and has garnered interest in the treatment of a variety of cancers, including leukemia and melanoma. As immune checkpoint...
Approved
Investigational
Matched Description: … (LAG-3). ... [L41265,L41300] It was the first anti-LAG-3 antibody to demonstrate benefit in a Phase 3 study, as well ... IgG4 monoclonal antibody and novel immune checkpoint inhibitor that targets lymphocyte activation gene-3 …
Matched Categories: … Lymphocyte Activation Gene-3 Blocker …

Everolimus

Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and...
Approved
Matched Iupac: … ,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3- …
Matched Products: … AFINITOR (3 MG DISPERSIBLE TABLETS) …

Pegvisomant

Pegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly. Unlike dopamine or somatostatin analogs (which inhibit growth hormone secretion), this drug actually blocks the hepatic (GH-mediated) production of insulin like growth factor (IGF-1), which is the main mediator of growth hormone activity.
Approved

Lenacapavir

HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens.[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy in vitro, little to no cross-resistance...
Approved
Investigational
Matched Iupac: … N-[(1S)-1-{3-[4-chloro-3-methanesulfonamido-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-(3-methanesulfonyl ... -3-methylbut-1-yn-1-yl)pyridin-2-yl}-2-(3,5-difluorophenyl)ethyl]-2-[(2S,4R)-5,5-difluoro-9-(trifluoromethyl …

Amrinone

Amrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.
Approved
Matched Description: … Amrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. …
Matched Categories: … Phosphodiesterase 3 Inhibitors …

Adenine

A purine base and a fundamental unit of adenine nucleotides.
Approved
Nutraceutical
Matched Salts cas: … 2922-28-3 …
Matched Mixtures name: … As 3 ... Additive Solution Formula 3 As-3 ... As-3 …

Chloroxylenol

Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Products: … Ultradex Liq 3% ... Suite Scrub Foam Liq 3% ... Suite Scrub 1000 Liq 3% …

Cladosporium sphaerospermum

Cladosporium sphaerospermum is a fungus which can provoke allergic reactions. Cladosporium sphaerospermum extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 3 ... Mold Mix 3 ... Mold Mix 3 …

Xanthium strumarium pollen

Xanthium strumarium pollen is the pollen of the Xanthium strumarium plant. Xanthium strumarium pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 3 Weed Mix ... 3 Weed Mix ... 3 Weed Mix …

Spectinomycin

An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Approved
Investigational
Vet approved
Matched Salts cas: … 23312-56-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …

Aspergillus niger var. niger

Aspergillus niger var. niger is a fungus which can provoke allergic reactions. Aspergillus niger var. niger extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 3 ... Mold Mix 3 ... Mold Mix 3 …

Efbemalenograstim alfa

Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Matched Description: … This approval was contingent on positive results observed in two pivotal Phase 3 Studies GC-627-04 and …

Benzalkonium

Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA Label]. This salt is used in a great variety of international pharmaceutical products such...
Approved
Investigational
Matched Mixtures name: … Refill 3 ... 3-Step First Aid Kit ... 3 Step First Aid Kit …
Matched Products: … 3 Pack Scented Hand Sanitizer ... ISSENGARD 24 HAND SANITIZER 3 oz ... Tsum Tsum 3 Pack Hand Sanitizer TT0051WA …

Capivasertib

Hormone receptor (HR) positive, especially estrogen receptor-positive, HER2-negative breast cancer is the most common subtype of metastatic breast cancer, resulting in more than 400,000 deaths annually. Although endocrine-based therapy is the first line of treatment, resistance eventually emerges, leaving chemotherapy the only but often ineffective treatment left. Therefore, significant research...
Approved
Investigational
Matched Iupac: … 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidine-4-carboxamide …

Nitazoxanide

Nitazoxanide belongs to the class of drugs known as thiazolides. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria, in addition to viruses. This drug is effective in the treatment of...
Approved
Investigational
Vet approved

Glycerin

A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Mixtures name: … REFRESH Optive Mega-3 ... REFRESH Optive Mega-3 ... Xoul Cell Illuminating 3 Step Mask …
Matched Products: … SRB 3 Lighting White Nutri ... 3 en 1 Cleanser. Deep Cleansing ... Eros Extended Love 3 Top Level …

Acer saccharinum pollen

Acer saccharinum pollen is the pollen of the Acer saccharinum plant. Acer saccharinum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 3 Maple Pollen Mix ... 3 Maple Pollen Mix ... 3 Maple Pollen Mix …

Dihydrocodeine

Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of...
Approved
Illicit
Matched Salts cas: … 84824-87-3 …
Displaying drugs 251 - 275 of 8783 in total