Displaying drugs 2726 - 2750 of 7137 in total
ABT-751
ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.
Investigational
Matched Synonyms: … N-[2-(4-hydroxyanilino)-3-pyridinyl]-4-methoxybenzenesulfonamide ... N-[2-(4-hydroxyanilino)pyridin-3-yl]-4-methoxybenzenesulfonamide ... N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide …
Matched Iupac: … N-{2-[(4-hydroxyphenyl)amino]pyridin-3-yl}-4-methoxybenzene-1-sulfonamide …
Matched Iupac: … N-{2-[(4-hydroxyphenyl)amino]pyridin-3-yl}-4-methoxybenzene-1-sulfonamide …
GTX-758
GTX-758 is under investigation in clinical trial NCT01420861 (GTx-758 on Serum Prostate-specific Antigen (PSA) in Men With Castrate Resistant Prostate Cancer).
Investigational
Matched Iupac: … 3-fluoro-N-(4-fluorophenyl)-4-hydroxy-N-(4-hydroxyphenyl)benzamide …
PRI-724
PRI-724 is under investigation in clinical trial NCT03620474 (Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis).
Investigational
Matched Iupac: … (4-{[(6S,9S,9aS)-1-(benzylcarbamoyl)-2,9-dimethyl-4,7-dioxo-8-[(quinolin-8-yl)methyl]-octahydro-1H-pyrazino …
Pyridoxal
The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. [PubChem]
Experimental
Nutraceutical
Matched Synonyms: … 2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine ... 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde ... 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde …
Matched Iupac: … 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde …
Matched Description: … The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme …
Matched Salts cas: … 65-22-5 …
Matched Iupac: … 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde …
Matched Description: … The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme …
Matched Salts cas: … 65-22-5 …
APPD
Investigational
Matched Synonyms: … -L-TALO-HEPTOFURANURONAMIDE, 5-O-(5-AMINO-5-DEOXY-.BETA. ... -D-RIBOFURANOSYL)-1,6-DIDEOXY-1-(3,4-DIHYDRO-2,4-DIOXO-1(2H)-PYRIMIDINYL)-6-((4-OXO-4-(((4-(4-(4-(TRIFLUOROMETHOXY …
Matched Iupac: … 5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]ethyl]amino}-N-[(4-{4-[4- ... 4-{[(1S,2S)-2-{[(2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy}-1-carbamoyl-2-[(2S,3S,4R, …
Matched Iupac: … 5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]ethyl]amino}-N-[(4-{4-[4- ... 4-{[(1S,2S)-2-{[(2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy}-1-carbamoyl-2-[(2S,3S,4R, …
Alrizomadlin
Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Investigational
Matched Synonyms: … (3'r,4's,5'r)-4-((6-chloro-2-oxo-1,2-dihydro-spiro(indole-3,3'-pyrrolidin)e-4'-(3-chloro-2-fluoro -phenyl ... Bicyclo(2.2.2)octane-1-carboxylic acid, 4-((((3'r,4's,5'r)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1' ... 4-((3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine …
Matched Iupac: … 4-{[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane ... -1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid …
Matched Iupac: … 4-{[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane ... -1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid …
Vactosertib
Vactosertib is under investigation in clinical trial NCT03724851 (Vactosertib in Combination With Pembrolizumab in Metastatic Colorectal or Gastric Cancer).
Investigational
Matched Synonyms: … 2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl] …
Matched Iupac: … 2-fluoro-N-{[5-(6-methylpyridin-2-yl)-4-{[1,2,4]triazolo[1,5-a]pyridin-6-yl}-1H-imidazol-2-yl]methyl} …
Matched Iupac: … 2-fluoro-N-{[5-(6-methylpyridin-2-yl)-4-{[1,2,4]triazolo[1,5-a]pyridin-6-yl}-1H-imidazol-2-yl]methyl} …
Paxalisib
GDC-0084 is under investigation in clinical trial NCT03696355 (Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas).
Investigational
Matched Synonyms: … 5-(6,6-dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[3,4-e]purin-2-yl)pyrimidin-2-amine …
Matched Iupac: … 5-[6,6-dimethyl-4-(morpholin-4-yl)-6H,8H,9H-[1,4]oxazino[3,4-h]purin-2-yl]pyrimidin-2-amine …
Matched Iupac: … 5-[6,6-dimethyl-4-(morpholin-4-yl)-6H,8H,9H-[1,4]oxazino[3,4-h]purin-2-yl]pyrimidin-2-amine …
NM-004
Investigational
Matched Synonyms: … 5-(4-carboxymethyl-phenylazo)-2-hydroxy-benzoic acid ... 5-((e)-(4-(carboxymethyl)phenyl)azo)-2-hydroxy-benzoic acid ... Benzeneacetic acid, 4-(2-(3-carboxy-4-hydroxyphenyl)diazenyl)- …
Matched Iupac: … 5-[(1E)-2-[4-(carboxymethyl)phenyl]diazen-1-yl]-2-hydroxybenzoic acid …
Matched Iupac: … 5-[(1E)-2-[4-(carboxymethyl)phenyl]diazen-1-yl]-2-hydroxybenzoic acid …
WNT-974
WNT974 has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
Investigational
Matched Synonyms: … (2,4'-bipyridine)-5-acetamide, 2',3-dimethyl-N-(5-(2-pyrazinyl)-2-pyridinyl)- …
Matched Iupac: … 2-{2',3-dimethyl-[2,4'-bipyridine]-5-yl}-N-[5-(pyrazin-2-yl)pyridin-2-yl]acetamide …
Matched Iupac: … 2-{2',3-dimethyl-[2,4'-bipyridine]-5-yl}-N-[5-(pyrazin-2-yl)pyridin-2-yl]acetamide …
F-15599
Investigational
Matched Synonyms: … (3-chloro-4-fluorophenyl)-(4-fluoro-4-(((5-methylpyrimidin-2-ylmethyl)amino)methyl)piperidin-1-yl)methanone ... 4-piperidinemethanamine, 1-(3-chloro-4-fluorobenzoyl)-4-fluoro-n-((5-methyl-2-pyrimidinyl)methyl)- ... 3-chloro-4-fluorophenyl-(4-fluoro-4-(((5-methylpyrimidin-2-ylmethyl)amino)methyl)piperidin-1yl)methanone …
Matched Iupac: … {[1-(3-chloro-4-fluorobenzoyl)-4-fluoropiperidin-4-yl]methyl}[(5-methylpyrimidin-2-yl)methyl]amine …
Matched Categories: … Serotonin 5-HT1 Receptor Agonists …
Matched Iupac: … {[1-(3-chloro-4-fluorobenzoyl)-4-fluoropiperidin-4-yl]methyl}[(5-methylpyrimidin-2-yl)methyl]amine …
Matched Categories: … Serotonin 5-HT1 Receptor Agonists …
NEO-212
Investigational
Matched Synonyms: … Carbamic acid, n-((3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazin-8-yl)carbonyl)-, ((4s)-4 …
Matched Iupac: … [(4S)-4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]methyl N-{3-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine …
Matched Iupac: … [(4S)-4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]methyl N-{3-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine …
2,4-Diamino-5-phenyl-6-ethylpyrimidine
Experimental
Matched Synonyms: … 2,4-Diamino-6-ethyl-5-phenylpyrimidine …
Matched Name: … 2,4-Diamino-5-phenyl-6-ethylpyrimidine …
Matched Iupac: … 6-ethyl-5-phenylpyrimidine-2,4-diamine …
Matched Name: … 2,4-Diamino-5-phenyl-6-ethylpyrimidine …
Matched Iupac: … 6-ethyl-5-phenylpyrimidine-2,4-diamine …
Icaritin
Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
Investigational
Matched Iupac: … 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one …
4-butyl-5-propyl-1,3-selenazol-2-amine
Experimental
Matched Synonyms: … 2-amino-4-butyl-5-propylselenazole …
Matched Name: … 4-butyl-5-propyl-1,3-selenazol-2-amine …
Matched Iupac: … 4-butyl-5-propyl-1,3-selenazol-2-amine …
Matched Name: … 4-butyl-5-propyl-1,3-selenazol-2-amine …
Matched Iupac: … 4-butyl-5-propyl-1,3-selenazol-2-amine …
Castanospermine
Experimental
Ethyl (4R)-4-{[(2R,5S)-2-(4-fluorobenzyl)-6-methyl-5-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-4-oxoheptanoyl]amino}-5-[(3S)-2-oxo-3-pyrrolidinyl]pentanoate
Experimental
Matched Name: … Ethyl (4R)-4-{[(2R,5S)-2-(4-fluorobenzyl)-6-methyl-5-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-4-oxoheptanoyl ... ]amino}-5-[(3S)-2-oxo-3-pyrrolidinyl]pentanoate …
Matched Iupac: … ethyl (4R)-4-[(2S,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[(5-methyl-1,2-oxazol-3-yl)formamido]-4-oxoheptanamido ... ]-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate …
Matched Iupac: … ethyl (4R)-4-[(2S,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[(5-methyl-1,2-oxazol-3-yl)formamido]-4-oxoheptanamido ... ]-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate …
SGS-742
SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease.
Investigational
RTA 744
RTA 744 is a novel anthracycline derivative that crosses the blood-brain barrier and shows significant potential for the treatment of primary and metastatic brain cancers. Anthracyclines are one of the most broadly used and effective classes of cancer therapies; however, they are not used to treat brain cancers because current...
Investigational
AT-7519
AT7519 is a selective inhibitor of certain Cyclin Dependent Kinases (CDKs) leading to tumour regression. It is developed by Astex for the treatment of solid tumours and haematological malignancies.
Investigational
Matched Synonyms: … 4-{[(2,6-dichlorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamide …
Matched Iupac: … 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide …
Matched Iupac: … 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide …
MK-7145
MK-7145 has been used in trials studying the treatment of Hypertension and Renal Insufficiency.
Investigational
Matched Iupac: … 5-[(1R)-1-hydroxy-2-{4-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-1,3-dihydro-2-benzofuran-5-yl)ethyl]piperazin ... -1-yl}ethyl]-4-methyl-1,3-dihydro-2-benzofuran-1-one …
AEE-788
AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.
Investigational
Matched Iupac: … 6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine …
ABP-700
ABP-700 is under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy).
Investigational
Matched Iupac: … 1-(methoxycarbonyl)cyclopropyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate …
Displaying drugs 2726 - 2750 of 7137 in total