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Displaying drugs 2776 - 2800 of 3129 in total
Natural Killer Cell
Natural Killer (NK) cells originate and differentiate from hematopoietic stem cells through various signalling pathways involving cytokines and interleukins. These cells arise from CD34+ lymphoid progenitors and comprise 10-15% of all lymphocytes in human peripheral blood. Once completely differentiated, NK cells lack B (CD19-) and T(CD3-) lymphocyte markers and carry...
Investigational
Basifungin
Basifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , .
Experimental
Matched Categories: … Anti-Infective Agents …
Lenzilumab
Lenzilumab is under investigation in clinical trial NCT02546284 (Study of Lenzilumab in Previously Treated Patients With Chronic Myelomonocytic Leukemia (CMML)).
Investigational
Matched Categories: … Anti-Inflammatory Agents …
Solithromycin
Solithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.
Investigational
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Ethenzamide
Experimental
Matched Categories: … Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal …
Berbamine
Investigational
Matched Categories: … Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal …
scAAV9.U7.ACCA
scAAV9.U7.ACCA is a non-replicating recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding RNA. Developed by Nationwide Children’s Hospital, it is being investigated for the treatment of Duchenne muscular dystrophy.
Investigational
Formebolone
Formebolone, a derivative of androstane, is an anabolic androgenic steroid. It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened for in athletes. It is also classified by the US Drug Enforcement Administration as Schedule III drug in the Controlled Substances Act. It...
Experimental
Illicit
Matched Description: … It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened …
Nangibotide
Nangibotide is under investigation in clinical trial NCT04055909 (Efficacy, Safety and Tolerability of Nangibotide in Patients With Septic Shock).
Investigational
Matched Categories: … Anti-Inflammatory Agents …
Vesatolimod
Vesatolimod has been used in trials studying the treatment of Hepatitis B and Chronic Hepatitis B.
Investigational
Matched Categories: … Anti-Infective Agents …
Melarsoprol
Melarsoprol is under investigation in clinical trial NCT00330148 (Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis).
Investigational
Matched Categories: … Anti-Infective Agents …
Chlorine dioxide
Chlorine Dioxide has been used in trials studying the treatment of Halitosis.
Investigational
Matched Categories: … Anti-Infective Agents …
Andrographolide
Andrographolide (HMPL-004) is a botanical product extracted from a herb that occurs naturally in China. The herb has an extensive history of use in TCM for the treatment of upper respiratory tract infections and other inflammatory and infectious diseases.
Investigational
Matched Categories: … Anti-Infective Agents ... Anti-Inflammatory Agents …
Octenidine
Octenidine is under investigation in clinical trial NCT02697162 (Antiseptic-coated Intermittent Urinary Catheter).
Investigational
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Local …
SC-236
SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
Experimental
Investigational
Matched Categories: … Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal …
OSI-7836
OSI-7836 is a member of the nucleoside class of cytotoxic drugs of which gemcitabine is the market leader. OSI Pharmaceuticals develops OSI-7836 as a next-generation gemcitabine. The anti-tumor activity of OSI-7836 appeares to be less schedule dependent than gemcitabine. It is also more active than ara-C (another clinically used nucleoside...
Investigational
Matched Description: … The anti-tumor activity of OSI-7836 appeares to be less schedule dependent than gemcitabine. …
Olokizumab
Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation, energy and bone metabolism, and the acute phase response of the innate immune system. IL-6 pathway dysregulation is associated with chronic inflammation and lymphoproliferation, including in autoimmune conditions such as rheumatoid arthritis, Castleman disease, and cytokine release syndrome....
Investigational
Matched Description: … [A241185, A241175] Olokizumab is a humanized anti-IL-6 IgG4κ antibody that directly blocks gp130 binding …
Vilobelimab
Vilobelimab is a chimeric monoclonal immunoglobulin G4 (IgG4) antibody that binds to the soluble form of human C5a with high affinity. It consists of mouse anti-human complement factor 5a (C5a) monoclonal binding sites (variable regions of heavy and light chain regions) and human gamma 4 heavy chain and light kappa...
Investigational
Matched Description: … It consists of mouse anti-human complement factor 5a (C5a) monoclonal binding sites (variable regions …
Lucanthone
One of the schistosomicides, it has been replaced largely by hycanthone and more recently praziquantel. (From Martindale The Extrapharmacopoeia, 30th ed., p46). It is currently being tested as a radiation sensitizer.
Investigational
Matched Categories: … Anti-Infective Agents …
Displaying drugs 2776 - 2800 of 3129 in total