Displaying drugs 2801 - 2825 of 3071 in total
(E)-(4S,6S)-6-((S)-2-{(S)-2-[(FURAN-2-CARBONYL)-AMINO]-3-METHYL-BUTYRYLAMINO}-3-METHYL-BUTYRYLAMINO)-8-METHYL-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID ETHYL ESTER
Experimental
Matched Name: … METHYL-BUTYRYLAMINO}-3-METHYL-BUTYRYLAMINO)-8-METHYL-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID …
Cyclo(prolylglycyl)
NA-831 (Traneurocin), is under investigation in two clinical trials: NCT03538522 (completed, for mild cognitive impairment and Alzheimer’s disease) and NCT04452565 (unknown status, combination therapy with Atazanavir and Dexamethasone for COVID-19).
Experimental
Matched Synonyms: … (S)-Hexahydropyrrolo(1,2-a)pyrazine-1,4-dione-4-17O …
Matched Iupac: … (8aS)-octahydropyrrolo[1,2-a]pyrazine-1,4-dione …
Matched Description: … Alzheimer’s disease) and NCT04452565 (unknown status, combination therapy with Atazanavir and Dexamethasone ... is under investigation in two clinical trials: NCT03538522 (completed, for mild cognitive impairment and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (8aS)-octahydropyrrolo[1,2-a]pyrazine-1,4-dione …
Matched Description: … Alzheimer’s disease) and NCT04452565 (unknown status, combination therapy with Atazanavir and Dexamethasone ... is under investigation in two clinical trials: NCT03538522 (completed, for mild cognitive impairment and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
R107474
Investigational
Matched Synonyms: … 3-(2-(3,4-Dihydrobenzofuro(3,2-c)pyridin-2(1H)-yl)ethyl)-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one ... 3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one …
Inavolisib
Inavolisib (GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer).
Investigational
Matched Synonyms: … (2S)-2-((2-((4S)-4-(difluoromethyl)-2-oxo-3-oxazolidinyl)-5,6-dihydroimidazo(1,2-D)(1,4)benzoxazepin- ... propanamide, 2-((2-((4S)-4-(difluoromethyl)-2-oxo-3-oxazolidinyl)-5,6-dihydroimidazo(1,2-D)(1,4)benzoxazepin …
Matched Description: … GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and ... Endocrine and Targeted Therapies in Participants With Breast Cancer). ... Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With …
Matched Description: … GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and ... Endocrine and Targeted Therapies in Participants With Breast Cancer). ... Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With …
Telacebec
Investigational
Matched Synonyms: … 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperdinyl)phenyl)methyl)-imidazo(1,2-a)pyridine ... Imidazo(1,2-a)pyridine-3-carboxamide, 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperidinyl …
Matched Iupac: … 6-chloro-2-ethyl-N-[(4-{4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}phenyl)methyl]imidazo[1,2-a]pyridine …
Matched Iupac: … 6-chloro-2-ethyl-N-[(4-{4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}phenyl)methyl]imidazo[1,2-a]pyridine …
NNZ-2591
NNZ-2591 (cyclo-L-glycyl-L-2-allylproline) is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been chemically modified to increase its half-life, stability, and oral bioavailability. It is currently under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and...
Investigational
Matched Synonyms: … Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-8a-(2-propenyl)-, (8aR)- …
Matched Iupac: … (8aR)-8a-(prop-2-en-1-yl)-octahydropyrrolo[1,2-a]pyrazine-1,4-dione …
Matched Description: … insulin-like growth factor 1 (IGF-1), that has been chemically modified to increase its half-life, stability, and ... under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and ... It was granted Orphan Drug Designation by the FDA in October 2019[L11103] and was granted a patent by …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (8aR)-8a-(prop-2-en-1-yl)-octahydropyrrolo[1,2-a]pyrazine-1,4-dione …
Matched Description: … insulin-like growth factor 1 (IGF-1), that has been chemically modified to increase its half-life, stability, and ... under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and ... It was granted Orphan Drug Designation by the FDA in October 2019[L11103] and was granted a patent by …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Olutasidenib
Olutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved by the FDA in December 2022.[L44256,L44261] It is indicated for the treatment of relapsed or refractory acute myeloid leukemia (AML) in patients with a susceptible IDH1 mutation as determined by an FDA-approved test. IDH1 mutations are common in...
Approved
Investigational
Matched Synonyms: … (s)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2- ... 2-pyridinecarbonitrile, 5-(((1s)-1-(6-chloro-1,2-dihydro-2-oxo-3-quinolinyl)ethyl)amino)-1,6-dihydro- ... 5-(((1s)-1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2 …
Matched Iupac: … 5-{[(1S)-1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl]amino}-1-methyl-6-oxo-1,6-dihydropyridine-2 …
Matched Description: … Olutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved ... and gliomas (NCT03684811). ... in different types of cancer, such as gliomas, AML, intrahepatic cholangiocarcinoma, chondrosarcoma, and …
Matched Iupac: … 5-{[(1S)-1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl]amino}-1-methyl-6-oxo-1,6-dihydropyridine-2 …
Matched Description: … Olutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved ... and gliomas (NCT03684811). ... in different types of cancer, such as gliomas, AML, intrahepatic cholangiocarcinoma, chondrosarcoma, and …
Atorvastatin
Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Iupac: … 4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid …
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid ... lipid levels, and ultimately reduce the risk of cardiovascular disease. ... inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium …
Matched Salts name: … Atorvastatin calcium ... Atorvastatin calcium trihydrate …
Matched Categories: … atorvastatin and acetylsalicylic acid ... atorvastatin, acetylsalicylic acid and ramipril ... atorvastatin, acetylsalicylic acid and perindopril ... Fatty Acids ... Heptanoic Acids …
Matched Products: … Atorvastatin Calcium ... Atorvastatin calcium ... Atorvastatin Calcium (Amorphous) …
Matched Description: … hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid ... lipid levels, and ultimately reduce the risk of cardiovascular disease. ... inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium …
Matched Salts name: … Atorvastatin calcium ... Atorvastatin calcium trihydrate …
Matched Categories: … atorvastatin and acetylsalicylic acid ... atorvastatin, acetylsalicylic acid and ramipril ... atorvastatin, acetylsalicylic acid and perindopril ... Fatty Acids ... Heptanoic Acids …
Matched Products: … Atorvastatin Calcium ... Atorvastatin calcium ... Atorvastatin Calcium (Amorphous) …
1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine
Experimental
Matched Synonyms: … 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine …
Matched Name: … 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine …
Matched Iupac: … (2-aminoethoxy)[(2R)-2,3-bis(hexadecanoyloxy)propoxy]phosphinic acid …
Matched Categories: … Phosphatidic Acids …
Matched Name: … 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine …
Matched Iupac: … (2-aminoethoxy)[(2R)-2,3-bis(hexadecanoyloxy)propoxy]phosphinic acid …
Matched Categories: … Phosphatidic Acids …
1,2-Docosahexanoyl-sn-glycero-3-phosphoserine
Experimental
Matched Name: … 1,2-Docosahexanoyl-sn-glycero-3-phosphoserine …
Matched Iupac: … }oxy)propanoic acid ... 4,7,10,13,16,19-hexaenoyloxy]-2-[(4Z,7Z,10Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyloxy]propoxy](hydroxy)phosphoryl …
Matched Salts name: … 1,2-docosahexanoyl-sn-glycero-3-phosphoserine calcium …
Matched Iupac: … }oxy)propanoic acid ... 4,7,10,13,16,19-hexaenoyloxy]-2-[(4Z,7Z,10Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyloxy]propoxy](hydroxy)phosphoryl …
Matched Salts name: … 1,2-docosahexanoyl-sn-glycero-3-phosphoserine calcium …
1,2-icosapentoyl-sn-glycero-3-phosphoserine
Approved
Experimental
Matched Name: … 1,2-icosapentoyl-sn-glycero-3-phosphoserine …
Matched Iupac: … )oxy]propanoic acid ... 6,9,12,15,18-pentaenoyloxy]-3-[(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyloxy]propoxy}(hydroxy)phosphoryl …
Matched Salts name: … 1,2-icosapentoyl-sn-glycero-3-phosphoserine calcium …
Matched Iupac: … )oxy]propanoic acid ... 6,9,12,15,18-pentaenoyloxy]-3-[(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyloxy]propoxy}(hydroxy)phosphoryl …
Matched Salts name: … 1,2-icosapentoyl-sn-glycero-3-phosphoserine calcium …
ST-101
ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease.
Investigational
Matched Synonyms: … ST-101 (D-AMINO ACID PEPTIDE) …
Matched Description: … ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ... ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease. …
Matched Description: … ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ... ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease. …
BQ-788
Investigational
Matched Synonyms: … (((2r,6s)-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)-d-tryptophyl-, sodium …
Matched Iupac: … sodium (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … sodium (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cefadroxil
Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Approved
Vet approved
Withdrawn
Matched Iupac: … amino-2-(4-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Salts name: … Cefadroxil sodium ... Cefadroxil monohydrate …
Matched Products: … CEFADROXIL MONOHYDRATE …
Matched Salts name: … Cefadroxil sodium ... Cefadroxil monohydrate …
Matched Products: … CEFADROXIL MONOHYDRATE …
(1S)-1-C-{(2R)-6-[(2R)-2-Butanyl]-5,10-dihydroxy-4-oxo-1,2,3,4-tetrahydro-2-anthracenyl}-5-deoxy-1-O-methyl-D-xylulose
Experimental
Matched Synonyms: … 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYDROXY-7-(SEC-BUTYL)-ANTHRACENE …
Hexestrol
A synthetic estrogen that has been used as a hormonal antineoplastic agent.
Withdrawn
Matched Synonyms: … 4,4'-(1,2-diethylethylene)diphenol …
Matched Salts name: … Hexestrol diphosphate sodium …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Salts name: … Hexestrol diphosphate sodium …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Soraprazan
Investigational
Matched Synonyms: … (7r,8r,9r)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7,8,9,10-tetrahydroimidazo(1,2-h)(1,7)naphtyridin …
Matched Iupac: … (7R,8R,9R)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7H,8H,9H,10H-imidazo[1,2-h]1,7-naphthyridin-8-ol …
Matched Iupac: … (7R,8R,9R)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7H,8H,9H,10H-imidazo[1,2-h]1,7-naphthyridin-8-ol …
Amprenavir
Amprenavir is a protease inhibitor used to treat HIV infection.
Approved
Investigational
Matched Synonyms: … furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamate …
Matched Iupac: … oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2-yl]carbamate …
Matched Categories: … Amprenavir and Prodrugs ... Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2-yl]carbamate …
Matched Categories: … Amprenavir and Prodrugs ... Acids, Acyclic ... Carboxylic Acids …
N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid
Experimental
Matched Name: … carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid …
Matched Iupac: … -5-[(phosphonooxy)methyl]oxolan-2-yl]-1H-imidazol-5-yl}prop-2-enamido]phenyl}formamido)pentanedioic acid …
Matched Iupac: … -5-[(phosphonooxy)methyl]oxolan-2-yl]-1H-imidazol-5-yl}prop-2-enamido]phenyl}formamido)pentanedioic acid …
TTI-101
Investigational
Matched Synonyms: … Benzenesulfonamide, n-(1',2-dihydroxy(1,2'-binaphthalen)-4'-yl)-4-methoxy- …
Matched Iupac: … N-{1',2-dihydroxy-[1,2'-binaphthalen]-4'-yl}-4-methoxybenzene-1-sulfonamide …
Matched Iupac: … N-{1',2-dihydroxy-[1,2'-binaphthalen]-4'-yl}-4-methoxybenzene-1-sulfonamide …
Dolutegravir
Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity. Dolutegravir was developed by ViiV Healthcare...
Approved
Matched Description: … The effect of this drug has no homology in human host cells, which gives it excellent tolerability and ... [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013. …
Matched Salts name: … Dolutegravir sodium …
Matched Categories: … lamivudine and dolutegravir ... dolutegravir and rilpivirine ... lamivudine, abacavir and dolutegravir ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … DOLUTEGRAVIR SODIUM …
Matched Salts name: … Dolutegravir sodium …
Matched Categories: … lamivudine and dolutegravir ... dolutegravir and rilpivirine ... lamivudine, abacavir and dolutegravir ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … DOLUTEGRAVIR SODIUM …
Panax ginseng whole
Panax ginseng whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Hong Shen Whole ... Ren Shen Whole …
MK-4541
MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor.
Investigational
Matched Synonyms: … 9bS,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinolin-1-yl]carbamate …
Matched Iupac: … 6H,6aH,7H,8H,9H,9aH,9bH,10H,11H,11aH-indeno[5,4-f]quinolin-7-yl](2,2,2-trifluoroethoxy)carboximidic acid …
Matched Description: … MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). ... MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … 6H,6aH,7H,8H,9H,9aH,9bH,10H,11H,11aH-indeno[5,4-f]quinolin-7-yl](2,2,2-trifluoroethoxy)carboximidic acid …
Matched Description: … MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). ... MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Quinacrine
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Investigational
Matched Synonyms: … N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine …
Matched Description: … It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Description: … It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Bupivacaine
Bupivacaine is a widely used local anesthetic agent.
Approved
Investigational
Matched Mixtures name: … Bupivacaine Hydrochloride and Epinephrine ... Bupivacaine Hci and Epinephrine ... Bupivacaine Hydrochloride and Epinephrine …
Matched Categories: … bupivacaine and meloxicam …
Matched Products: … BUPIVACAINE HCL MONOHYDRATE …
Matched Categories: … bupivacaine and meloxicam …
Matched Products: … BUPIVACAINE HCL MONOHYDRATE …
Displaying drugs 2801 - 2825 of 3071 in total