Displaying drugs 2826 - 2850 of 3563 in total
Mavodelpar
Investigational
Matched Synonyms: … REN-001 free acid …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Chloroprocaine
Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Synonyms: … 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl ester …
Matched Description: … [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... [L43402] The pharmacological profile of chloroprocaine is characterized by a short latency and duration ... Both can be given as intrathecal injections for peripheral and central nerve block, but only the preservative-free …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
Matched Description: … [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... [L43402] The pharmacological profile of chloroprocaine is characterized by a short latency and duration ... Both can be given as intrathecal injections for peripheral and central nerve block, but only the preservative-free …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
RU85053
Experimental
Matched Synonyms: … Acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]propyl]-2-(carboxymethyl)benzoic acid …
Matched Iupac: … [1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl)benzoic acid …
Matched Iupac: … [1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl)benzoic acid …
Acrivastine
Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and tachycardia.
Acrivastine is...
Approved
Matched Synonyms: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... , edema, bronchoconstriction, and tachycardia. ... As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby …
Matched Categories: … Drugs that are Mainly Renally Excreted …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... , edema, bronchoconstriction, and tachycardia. ... As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby …
Matched Categories: … Drugs that are Mainly Renally Excreted …
Cianidanol
An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Approved
Withdrawn
Matched Synonyms: … Catechuic acid …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
NP-51
Investigational
Matched Synonyms: … (+/-)-o-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoxime …
Vipoglanstat
Investigational
Matched Synonyms: … dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2-difluoroethoxy)-1-methyl-1H-benzoimidazole-5-carboxylic acid …
Perindopril
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Synonyms: … 3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid …
Matched Iupac: … 3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and ... be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and …
Matched Mixtures name: … PRETERAX® ARG 2.5 MG ... Apo-perindopril-indapamide ... Apo-perindopril-indapamide …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... atorvastatin, acetylsalicylic acid and perindopril ... ACE Inhibitors and Diuretics ... perindopril and diuretics ... perindopril and bisoprolol …
Matched Products: … COVEREX-AS ... Ag-perindopril ... Apo-perindopril …
Matched Iupac: … 3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and ... be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and …
Matched Mixtures name: … PRETERAX® ARG 2.5 MG ... Apo-perindopril-indapamide ... Apo-perindopril-indapamide …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... atorvastatin, acetylsalicylic acid and perindopril ... ACE Inhibitors and Diuretics ... perindopril and diuretics ... perindopril and bisoprolol …
Matched Products: … COVEREX-AS ... Ag-perindopril ... Apo-perindopril …
Trioxsalen
Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative obtained from several plants, mainly Psoralea corylifolia. Like other psoralens it causes photosensitization of the skin. It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of...
Approved
Matched Synonyms: … 6-hydroxy-β,2,7-trimethyl-5-benzofuranacrylic acid, δ-lactone …
Matched Description: … Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative ... light) for phototherapy treatment of vitiligo and hand eczema. ... In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage …
Matched Description: … Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative ... light) for phototherapy treatment of vitiligo and hand eczema. ... In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage …
Indoximod
Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.
Investigational
Matched Synonyms: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Matched Description: … Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Matched Description: … Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Gavorestat
Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia).
Investigational
Matched Synonyms: … AT-007 ... Oxo-3-((5-(Trifluoromethyl)Benzo[D]Thiazol-2-Yl)Methyl)-3,4-Dihydrothieno[3,4-D]Pyridazin-1-Yl)Acetic Acid …
Matched Iupac: … -oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3H,4H-thieno[3,4-d]pyridazin-1-yl)acetic acid …
Matched Description: … Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD ... Study of AT-007 in Pediatric Subjects With Classic Galactosemia). …
Matched Iupac: … -oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3H,4H-thieno[3,4-d]pyridazin-1-yl)acetic acid …
Matched Description: … Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD ... Study of AT-007 in Pediatric Subjects With Classic Galactosemia). …
Desmopressin
Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body. Upon release from the...
Approved
Matched Synonyms: … 1-(3-mercaptopropionic acid)-8-D-arginine-vasopressin …
Matched Description: … a prolonged half-life and duration of action compared to endogenous ADH [A31661]. ... drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ... solution, intravenous solution, oral tablet and oral lyophilisate [A31662]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Apo-desmopressin …
Matched Description: … a prolonged half-life and duration of action compared to endogenous ADH [A31661]. ... drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ... solution, intravenous solution, oral tablet and oral lyophilisate [A31662]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Apo-desmopressin …
Repotrectinib
Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...
Approved
Investigational
Matched Synonyms: … (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN …
Matched Description: … [A262056] ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ... with resistance mutation hotspots and targets mutations in the solvent-front region. ... resistance to multiple TKI has been reported, including [crizotinib], [lorlatinib], [taletrectinib], and …
Matched Description: … [A262056] ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ... with resistance mutation hotspots and targets mutations in the solvent-front region. ... resistance to multiple TKI has been reported, including [crizotinib], [lorlatinib], [taletrectinib], and …
Dersimelagon
Investigational
Matched Synonyms: … pyrrolidine-3-carbonyl)-4-(methoxymethyl)pyrrolidin-3-yl)-5-(trifluoromethyl)phenyl)piperidine-4-carboxylic acid ... 4-piperidinecarboxylic acid, 1-(2-((3s,4r)-1-(((3r,4r)-1-cyclopentyl-3-fluoro-4-(4-methoxyphenyl)-3-pyrrolidinyl …
Matched Iupac: … pyrrolidine-3-carbonyl]-4-(methoxymethyl)pyrrolidin-3-yl]-5-(trifluoromethyl)phenyl}piperidine-4-carboxylic acid …
Matched Iupac: … pyrrolidine-3-carbonyl]-4-(methoxymethyl)pyrrolidin-3-yl]-5-(trifluoromethyl)phenyl}piperidine-4-carboxylic acid …
Fotemustine
Investigational
Matched Synonyms: … PHOSPHONIC ACID, (1-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)AMINO)ETHYL)-, DIETHYL ESTER ... PHOSPHONIC ACID, P-(1-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)AMINO)ETHYL)-, DIETHYL ESTER …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Terbinafine
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues ... Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. ... ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … Live Better Antifungal ... Lamisil At ... Lamisil AT …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … Live Better Antifungal ... Lamisil At ... Lamisil AT …
3'-Fluoro-3'-deoxythymidine 5'-monophosphate
Experimental
Matched Synonyms: … 5'-Thymidylic acid, 3'-deoxy-3'-fluoro- …
Matched Iupac: … ,5R)-3-fluoro-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid …
Matched Iupac: … ,5R)-3-fluoro-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid …
S-(N-hydroxy-N-iodophenylcarbamoyl)glutathione
Experimental
Matched Synonyms: … carboxymethylamino)-3-[(R)-hydroxy-(N-hydroxy-4-iodoanilino)methyl]sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid …
Matched Iupac: … carboxymethyl)carbamoyl]-2-{[(R)-hydroxy[hydroxy(4-iodophenyl)amino]methyl]sulfanyl}ethyl]carbamoyl}butanoic acid …
Matched Iupac: … carboxymethyl)carbamoyl]-2-{[(R)-hydroxy[hydroxy(4-iodophenyl)amino]methyl]sulfanyl}ethyl]carbamoyl}butanoic acid …
L-Saccharopine
Experimental
Matched Synonyms: … N-[(S)-5-Amino-5-carboxypentyl]-L-glutamic acid …
Matched Iupac: … (2S)-2-{[(5S)-5-amino-5-carboxypentyl]amino}pentanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Matched Iupac: … (2S)-2-{[(5S)-5-amino-5-carboxypentyl]amino}pentanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Carindacillin
Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Approved
Investigational
Matched Synonyms: … 6β-{2-[(2,3-dihydro-1H-inden-5-yloxy)carbonyl]-2-phenylacetamido}-2,2-dimethylpenam-3α-carboxylic acid …
Matched Iupac: … yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … Pfizer as Geocillin. ... Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of [carbenicillin] marketed by …
Matched Iupac: … yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … Pfizer as Geocillin. ... Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of [carbenicillin] marketed by …
NNC-55-0396 free base
NNC-55-0396 is a T-type Ca(2+) channel inhibitor.
Investigational
Matched Synonyms: … Cyclopropanecarboxylic acid, (1s,2s)-2-(2-((3-(1h-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro …
Matched Description: … NNC-55-0396 is a T-type Ca(2+) channel inhibitor.[A253047] …
Matched Description: … NNC-55-0396 is a T-type Ca(2+) channel inhibitor.[A253047] …
Sivopixant
Investigational
Matched Synonyms: … 1,3,5-triazine-1(2h)-propanoic acid, 3-((4-chlorophenyl)methyl)tetrahydro-.alpha. …
TBI-223
TBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis).
Investigational
Matched Synonyms: … CARBAMIC ACID, N-(((5S)-3-(3-FLUORO-4-(2-OXA-6-AZASPIRO(3.3)HEPT-6-YL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL …
Displaying drugs 2826 - 2850 of 3563 in total