Displaying drugs 2851 - 2875 of 3652 in total
Aztreonam
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Synonyms: … thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid ... {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene]amino}oxy)-2-methylpropanoic acid …
Matched Description: … It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges ... , bladder, and kidneys. ... A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. …
Matched Categories: … beta-Lactams …
Matched Description: … It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges ... , bladder, and kidneys. ... A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. …
Matched Categories: … beta-Lactams …
MK-4541
MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor.
Investigational
Matched Synonyms: … 9bS,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinolin-1-yl]carbamate …
Matched Iupac: … 6H,6aH,7H,8H,9H,9aH,9bH,10H,11H,11aH-indeno[5,4-f]quinolin-7-yl](2,2,2-trifluoroethoxy)carboximidic acid …
Matched Description: … MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase ... MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … 6H,6aH,7H,8H,9H,9aH,9bH,10H,11H,11aH-indeno[5,4-f]quinolin-7-yl](2,2,2-trifluoroethoxy)carboximidic acid …
Matched Description: … MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase ... MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
1-O-[O-Nitrophenyl]-Beta-D-Galactopyranose
Includes ortho-, meta-, and para-nitrophenylgalactosides. [PubChem]
Experimental
Matched Name: … 1-O-[O-Nitrophenyl]-Beta-D-Galactopyranose …
Matched Description: … Includes ortho-, meta-, and para-nitrophenylgalactosides. [PubChem] …
Matched Description: … Includes ortho-, meta-, and para-nitrophenylgalactosides. [PubChem] …
Gamma-Arsono-Beta, Gamma-Methyleneadenosine-5'-Diphosphate
Adenylic acid. Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. [PubChem]
Experimental
Matched Name: … Gamma-Arsono-Beta, Gamma-Methyleneadenosine-5'-Diphosphate …
Matched Iupac: … 9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[(arsonomethyl)(hydroxy)phosphoryl]oxy})phosphinic acid …
Matched Description: … Adenylic acid. …
Matched Iupac: … 9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[(arsonomethyl)(hydroxy)phosphoryl]oxy})phosphinic acid …
Matched Description: … Adenylic acid. …
Beta-1,2,3,4,6-Penta-O-Galloyl-D-Glucopyranose
Experimental
Matched Name: … Beta-1,2,3,4,6-Penta-O-Galloyl-D-Glucopyranose …
N-acetyl-N'-beta-D-glucopyranosyl urea
Experimental
Matched Name: … N-acetyl-N'-beta-D-glucopyranosyl urea …
[4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE]
Experimental
Matched Name: … [4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE] …
Matched Iupac: … (2S,4aR,6R,7S,8R,8aS)-6,7,8-trihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxine-2-carboxylic acid …
Matched Iupac: … (2S,4aR,6R,7S,8R,8aS)-6,7,8-trihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxine-2-carboxylic acid …
PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE
Experimental
Matched Name: … PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE …
Dinoprostone
Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Matched Synonyms: … (5Z,11α,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid ... (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid ... (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Description: … As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce …
Matched Categories: … Genito Urinary System and Sex Hormones ... Fatty Acids ... Fatty Acids, Unsaturated …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Description: … As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce …
Matched Categories: … Genito Urinary System and Sex Hormones ... Fatty Acids ... Fatty Acids, Unsaturated …
MALP-2
Investigational
Matched Synonyms: … -aspartyl-l-.alpha. ... -glutamyl-l-seryl-l-asparaginyl-l-isoleucyl-l-seryl-l-phenylalanyl-l-lysyl-l-.alpha.-glutamyl- ... L-lysine, s-((2r)-2,3-bis((1-oxohexadecyl)oxy)propyl)-l-cysteinylglycyl-l-asparaginyl-l-asparaginyl-l-.alpha …
Matched Iupac: … methylpentanamido]-3-hydroxypropanamido]-3-phenylpropanamido]hexanamido]-4-carboxybutanamido]hexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … methylpentanamido]-3-hydroxypropanamido]-3-phenylpropanamido]hexanamido]-4-carboxybutanamido]hexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Teniposide
Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic...
Approved
Matched Synonyms: … 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside) …
Matched Description: … Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... Teniposide acts primarily in the G2 and S phases of the cycle. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... Teniposide acts primarily in the G2 and S phases of the cycle. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
FG-2216
A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.
Investigational
Matched Synonyms: … (((1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl)amino)acetic acid …
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid …
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid …
THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE
Experimental
Matched Name: … THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL] …
Matched Iupac: … N-[(3S)-2-oxo-1-({1H-pyrrolo[2,3-c]pyridin-2-yl}methyl)pyrrolidin-3-yl]thieno[3,2-b]pyridine-2-sulfonamide …
Matched Iupac: … N-[(3S)-2-oxo-1-({1H-pyrrolo[2,3-c]pyridin-2-yl}methyl)pyrrolidin-3-yl]thieno[3,2-b]pyridine-2-sulfonamide …
Cyclic adenosine monophosphate
Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
Experimental
Matched Synonyms: … Cyclic adenylic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Tagetitoxin
Tagetitoxin is a bacterial phytotoxin. It preferentially inhibits eukaryotic RNA polymerase.
Experimental
Matched Synonyms: … Acetoxy-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Iupac: … acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Cerulenin
Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Matched Synonyms: … (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide …
Matched Iupac: … (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboximidic acid …
Matched Description: … and sterols. ... It is also shown to inhibit feeding and induce dramatic weight loss in mice. ... In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. …
Matched Categories: … Fatty Acid Synthesis Inhibitors …
Matched Iupac: … (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboximidic acid …
Matched Description: … and sterols. ... It is also shown to inhibit feeding and induce dramatic weight loss in mice. ... In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. …
Matched Categories: … Fatty Acid Synthesis Inhibitors …
Magnesium phosphate
Experimental
Matched Synonyms: … Phosphoric acid, magnesium salt (2:3) …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Acids ... Acids, Noncarboxylic ... Phosphoric Acids …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Acids ... Acids, Noncarboxylic ... Phosphoric Acids …
C-(1-Azido-Alpha-D-Glucopyranosyl) Formamide
Experimental
Matched Name: … C-(1-Azido-Alpha-D-Glucopyranosyl) Formamide …
5beta-dihydrotestosterone
Experimental
Matched Synonyms: … 5-beta-DHT ... etiocholan-17-beta-ol-3-one …
Matched Categories: … Testosterone and derivatives …
Matched Categories: … Testosterone and derivatives …
Molibresib
Molibresib is under investigation in clinical trial NCT01943851 (A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and Clinical Activity of GSK525762 in Subjects With Relapsed, Refractory Hematologic Malignancies).
Investigational
Matched Synonyms: … Bet inhibitor gsk525762 …
Matched Description: … NCT01943851 (A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and …
Matched Description: … NCT01943851 (A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and …
Ganciclovir
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Salts name: … Ganciclovir sodium …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … GANCICLOVIR SODIUM FOR INJECTION …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … GANCICLOVIR SODIUM FOR INJECTION …
4-{2,4-Bis[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid
Experimental
Matched Name: … 4-{2,4-Bis[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid …
Matched Iupac: … 4-[2,4-bis(3-nitrobenzamido)phenoxy]benzene-1,2-dicarboxylic acid …
Matched Iupac: … 4-[2,4-bis(3-nitrobenzamido)phenoxy]benzene-1,2-dicarboxylic acid …
N-Pyridoxyl-7-Keto-8-Aminopelargonic Acid-5'-Monophosphate
Experimental
Matched Name: … N-Pyridoxyl-7-Keto-8-Aminopelargonic Acid-5'-Monophosphate …
Matched Iupac: … (8S)-8-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-7-oxononanoic acid …
Matched Iupac: … (8S)-8-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-7-oxononanoic acid …
4-oxo-4,5-dihydro-1,2,5-thiadiazole-3-carboxylic acid
Experimental
Matched Name: … 4-oxo-4,5-dihydro-1,2,5-thiadiazole-3-carboxylic acid …
Matched Iupac: … 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid …
Matched Iupac: … 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid …
6-phenyl-4(R)-(7-phenyl-heptanoylamino)-hexanoic acid
Experimental
Matched Name: … 6-phenyl-4(R)-(7-phenyl-heptanoylamino)-hexanoic acid …
Matched Iupac: … (4R)-6-phenyl-4-(7-phenylheptanamido)hexanoic acid …
Matched Iupac: … (4R)-6-phenyl-4-(7-phenylheptanamido)hexanoic acid …
Displaying drugs 2851 - 2875 of 3652 in total