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Displaying drugs 2851 - 2875 of 3348 in total

Insulin glulisine

Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … B3 is replaced by lysine and the lysine at position B29 is replaced by glutamic acid. ... a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening ... Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … APIDRA 100 Units/ml Solution for Injection in vial ... APIDRA 100 U/ML- SOLUTION FOR INJECTION IN VIAL ... Apidra SoloStar 100 Units/ml Solution for injection in a pre-filled pen …

Atracurium besylate

A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.
Approved
Matched Description: … Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for …
Matched Products: … Atracurium - (for Single Dose ) ... Atracurium Kabi 10mg/ml Solution for Injection USP ... ATRACURIUM LABATEC IV SOLUTION FOR INJECTION 10MG/ML …

Ixabepilone

Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer. Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. Ixabepilone is...
Approved
Investigational
Matched Description: … Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. ... It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … IXEMPRA FOR INJECTION 15 MG ... IXEMPRA (FOR INJECTION 15 MG) ... IXEMPRA FOR INJECTION 45 MG …

Fenthion

Fenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is listed as a restricted use compound by the United States Environmental Protection Agency due to its potential to cause cholinesterase...
Vet approved
Matched Synonyms: … Phosphorothioic acid, O,O-dimethyl O-(3-methyl-4-(methylthio)phenyl) ester …
Matched Description: … Fenthion is an _organothiophosphate_ drug used as an insecticide, avicide, and acaricide. ... States Environmental Protection Agency due to its potential to cause cholinesterase inhibition in humans and …

Pabinafusp alfa

Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … HUMAN-MUS MUSCULUS MONOCLONAL JR-141 .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …

Methoxy polyethylene glycol-epoetin beta

Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Mircera Solution for Injection 100mcg/0.3ml (Pre-filled Syringe) ... Mircera Solution for Injection 75mcg/0.3ml (Pre-filled Syringe) ... Mircera Solution for Injection 50mcg/0.3ml (Pre-filled Syringe) …

Clofarabine

Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic...
Approved
Investigational
Matched Description: … It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. ... Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … EVOLTRA 1 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION ... NUCLOFAR Clofarabine 1mg/mL Concentrate for Solution for Infusion ... Evoltra Concentrate Solution for Infusion 1mg/ml …

Azithromycin

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Description: … It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be ... used instead of other macrolides for some sexually transmitted and enteric infections. ... Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue …
Matched Categories: … cefixime and azithromycin ... Macrolides, Lincosamides and Streptogramins ... azithromycin, fluconazole and secnidazole ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Zithrolide 500mg Powder for Solution for Infusion ... Azithromycin powder for solution for injection 500mg ... ZITHROMAX IV POWDER FOR SOLUTION FOR INFUSION 500 mg/vial …

Dalosirvat

Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and Safety of SM04554 Topical Solution in Male Subjects With Androgenetic Alopecia).
Investigational
Matched Synonyms: … 1-(2,3-dihydro-benzo(1,4)dioxin-6-yl)-4-phenyl-butane-1,4-dione …
Matched Description: … Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and …

Bemiparin

Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower...
Approved
Investigational
Matched Description: … Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins ... tumors and diabetic foot ulcers [L1468, A7866]. ... These heparins have lower anti-thrombin activity than the traditional low molecular weight heparins and …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … HIBOR 2,500 IU ANTI XA/0.2ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGES ... HIBOR 10,000 IU ANTI XA/0.4 ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGES ... HIBOR 3,500 IU ANTI XA/0.2 ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGES …

Denosumab

Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … 215 amino acids and each heavy chain consisting of 448 amino acids with 4 intramolecular disulfides. ... receiving androgen deprivation therapy for non-metastatic prostate cancer and women at high risk for ... fracture receiving adjuvant aromatase inhibitor therapy for breast cancer in September 2011 and in men …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Drugs for Treatment of Bone Diseases …
Matched Products: … XGEVA 120mg Solution for Injection ... XGEVA Solution for Injection 120 mg/vial ... Prolia Solution for Injection 60mg Pre-filled Syringe …

Galcanezumab

Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP). Although several small-molecule CGRP receptor antagonists have been developed, humanized monoclonal antibodies like galcanezumab are specifically designed to selectively bind to CGRP entities with high potency. Given this target specificity, lack of...
Approved
Investigational
Matched Description: … [A33112] Galcanezumab was approved by the FDA in September 2018, and is indicated for the preventive ... promising safety and tolerability. ... Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED PEN 120 MG/ML ... Pontevia 120 mg solution for injection in pre-filled pen ... Pontevia 120 mg solution for injection in pre-filled syringe …

Cyclophosphamide

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects,...
Approved
Investigational
Matched Description: … in the liver to form the active aldophosphamide. ... It has been used in the treatment of lymphoma and leukemia. ... Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated …
Matched Mixtures name: … Procytox for Injection 2000mg Pws IV …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Cytoxan Pws for Inj 1000mg/vial ... Cytoxan Pws for Inj 2000mg/vial ... CYCRAM FOR INJECTION 1 g/vial …

Acetazolamide

One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched Description: … (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) ... It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures ... anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Acetazolamide 500mg Powder for Solution for Injection ... Acetazolamide for Injection USP ... Acetazolamide for Injection, USP …

Ferric derisomaltose

Iron deficiency is an extremely common condition and is the most frequent cause of anemia worldwide. Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells. Though it is generally considered non...
Approved
Matched Description: … is associated with other forms of injectable iron. ... [A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. ... [L11581,L11587] Clinical trials show that it is non-inferior to [iron sucrose], another form of iron …
Matched Products: … MONOFER® SOLUTION FOR INJECTION OR INFUSION 100 MG/ML ... Monofer 100 mg/ml solution for injection/infusion in vials ... Monofer 100mg/ml solution for injection/infusion in ampoules …

Burosumab

Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … (XLH), which is a rare, inherited form of rickets. ... It causes impaired bone growth and development in children and adolescents and issues with bone mineralization ... This is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Drugs for Treatment of Bone Diseases …
Matched Products: … CRYSVITA® SOLUTION FOR INJECTION 10 MG/ML ... CRYSVITA® SOLUTION FOR INJECTION 30 MG/ML ... CRYSVITA® SOLUTION FOR INJECTION 20 MG/ML …

Corifollitropin alfa

Corifollitropin alfa, also known as Elonva is used in women undergoing fertility treatment to stimulate the development of more than one mature egg (oocyte) at a time in the ovaries. This drug used together with a gonadotropin-releasing hormone (GnRH) antagonist, a type of medicine also used in fertility treatments. Elonva...
Approved
Investigational
Matched Description: … Multiple studies and a meta-analysis suggest that corifollitropin alfa is as efficacious as recombinant ... FDA for its New Drug Application for this drug. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Elonva Solution for Injection 150mcg/0.5ml ... Elonva Solution for Injection 100mcg/0.5ml ... Elonva (solution for injection 100mcg/0.5ml) …

Evolocumab

Evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen. It is a subcutaneous injection approved by the FDA for individuals on maximum statin therapy who still require additional LDL-cholesterol lowering. It is approved for both homozygous and heterozygous familial cholesterolemia as an adjunct to other first-line...
Approved
Matched Description: … It is approved for both homozygous and heterozygous familial cholesterolemia as an adjunct to other first-line ... Evolocumab is designed to bind to PCSK9 and inhibit PCSK9 from binding to LDL receptors on the liver ... Evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …
Matched Products: … REPATHA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 140MG/ML ... Repatha Solution for Injection in Pre-filled Syringe 140mg/mL (evolocumab) ... REPATHA SOLUTION FOR INJECTION IN PRE-FILLED AUTOINJECTOR 140MG/ML …

Fondaparinux

Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Iupac: … -hydroxy-6-methoxy-5-(sulfoamino)-2-[(sulfooxy)methyl]oxan-3-yl]oxy}-5-(sulfooxy)oxane-2-carboxylic acid …
Matched Description: … The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural ... Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and ... It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … ARIXTRA 12.5MG/ML SOLUTION FOR INJECTION ... ARIXTRA 2.5MG/0.5ML SOLUTION FOR INJECTION ... Arixtra Solution for Injection 7.5 mg/0.6 ml …

5-(6-Amino-9h-Purin-9-Yl)-4-Hydroxytetrahydrofuran-3-Yl Dihydrogen Phosphate

Experimental
Matched Name: … 5-(6-Amino-9h-Purin-9-Yl)-4-Hydroxytetrahydrofuran-3-Yl Dihydrogen Phosphate …
Matched Iupac: … {[(3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid …

Fulvestrant

Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. While it is used as monotherapy for the...
Approved
Investigational
Matched Description: … It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and ... While it is used as monotherapy for the treatment of breast cancers, it is also used in combination with ... [alpelisib] for the treatment of HR-positive, human epidermal growth factor receptor 2 (HER2)-negative …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FASLODEX SOLUTION FOR INJECTION 250MG/5 ML ... FEMCORD SOLUTION FOR INJECTION 250 MG/5 ML ... Faslodex Solution For Injection 250 mg/5ml …

Dexmedetomidine

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … ICUNES® 100mcg/ml Concentrate for Solution for Infusion ... PRECEDEX CONCENTRATE FOR SOLUTION FOR INFUSION 100 mcg/ml (Vial) ... Dexmedetomidine Hydrochloride for Injection …

Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate

Tetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.
Approved
Matched Description: … copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for …
Matched Products: … Kit for the Preparation of Technetium Tc99m Sestamibi ... Stamicis Kit for Radiopharmaceutical Preparation 1mg ... STAMICIS 1 mg Kit for Radiopharmaceutical Preparation …

Pemetrexed

Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for...
Approved
Investigational
Matched Iupac: … )-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioic acid …
Matched Description: … Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the ... It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural ... mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative surgery …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Matched Products: … Pemirex powder for concentrate for solution for infusion 500mg ... Pemirex powder for concentrate for solution for infusion 100mg ... PODOXRED POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 500MG …

Busulfan

Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Alkanesulfonic Acids ... Sulfur Acids ... Sulfonic Acids …
Matched Products: … Busulfan Kabi Injection 6mg/ml Concentrate for Solution for Infusion ... Busulfan for Injection ... CANBUSUL- Busulfan Injection 6 mg/ml Concentrate for Solution for Infusion …
Displaying drugs 2851 - 2875 of 3348 in total