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Displaying drugs 276 - 300 of 8872 in total

Olopatadine

Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Iupac: … 2-[(2Z)-2-[3-(dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen …
Matched Categories: … Heterocyclic Compounds, 3-Ring …

Calcitriol

Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to DB00169 (vitamin D3)...
Approved
Nutraceutical
Matched Description: … D3. ... Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred ... to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin …
Matched Products: … SILKIS OINTMENT 3 mcg/g …

Nebivolol

Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Description: … [A182594] Nebivolol was granted FDA approval on 17 December 2007.[L7985] …

Aclidinium

Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Approved
Matched Iupac: … (3R)-3-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azabicyclo[2.2.2]octan-1-ium …

Pramipexole

Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). It is a non-ergot dopamine agonist drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) . It was first approved by the FDA in 1997 . Parkinson's Disease is...
Approved
Investigational
Matched Products: … PEXA XR 3 MG UZATILMIŞ SALIMLI TABLET, 30 ADET ... PEXOLA ER 3 MG UZATILMIS SALIMLI TABLET, 30 ADET ... PARKİPEX ER 3 MG UZATILMIŞ SALIMLI TABLET, 30 ADET …

Ergosterol

A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
Approved
Experimental
Matched Iupac: … (1R,3aR,7S,9aR,9bS,11aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-9a,11a-dimethyl-1H,2H,3H,3aH,6H,7H …

Nomifensine

Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Description: … Merital capsules were removed from the market for safety reasons (see the Federal Register of June 17 …

Valproic acid

Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational

Human thrombin

Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. This transformation mimics the final coagulation cascade step which involves the clotting mass...
Approved

Estradiol benzoate

Estradiol Benzoate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream...
Approved
Investigational
Vet approved

Rezafungin

Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational

Pimethixene

Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. It is an anticholinergic used in the treatment of bronchitis.
Approved
Matched Categories: … Heterocyclic Compounds, 3-Ring …

Ketoconazole

Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Products: … KETORAL 400 MG VAJİNAL SUPOZİTUVAR, 3 ADET …

Soybean oil

Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated fatty acids. It is a complex mixture of triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g of monounsaturated fat, and 58 g of polyunsaturated fat. The...
Approved
Matched Description: … The major component fatty acids are linoleic (48% - 58%), oleic (17% - 30%), palmitic (9% -13%), linolenic …

Dimetotiazine

Dimetotiazine has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions.
Approved
Matched Categories: … Heterocyclic Compounds, 3-Ring …

Mirabegron

Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence. It is unique amongst overactive bladder treatment options in that, unlike other treatments such as solifenacin and darifenacin, it lacks significant antimuscarinic activity, which is...
Approved
Matched Description: … Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of …
Matched Categories: … Adrenergic beta-3 Receptor Agonists ... Selective Beta 3-adrenergic Agonists …

Ethanol

A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Approved
Matched Mixtures name: … 3 Hand Sanitizers ... 3 Hand Sanitizers ... 3 Hand Sanitizers …
Matched Products: … Alpha E-3 ... Bortek E-3 ... Lewcizer 3 …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Products: … ENGERIX-B ERİŞKİN 20 MCG/ 1ML ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTOR, 3 DOZ …

Ivosidenib

Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. IDH1 is an enzyme that is often mutated and overexpressed in some cancers, leading to aberrant cell growth and proliferation. Ivosidenib inhibits mutated IDH1, blocking the enzymatic activity and further differentiation of cancer cells. Ivosidenib was granted accelerated approval by the FDA...
Approved
Investigational
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-{1-[(2S)-1-(4-cyanopyridin-2-yl)-5-oxopyrrolidin-2-yl]-N-(5-fluoropyridin-3- …

Doxercalciferol

Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment...
Approved
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden …
Matched Description: … disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 …

Metixene

Metixene (or methixene) is a anticholinergic used as an antiparkinsonian agent.
Approved
Matched Iupac: … 1-methyl-3-[(9H-thioxanthen-9-yl)methyl]piperidine …
Matched Categories: … Heterocyclic Compounds, 3-Ring …

Penicillium chrysogenum var. chrysogenum

Penicillium chrysogenum var. chrysogenum is a fungus which can provoke allergic reactions. Penicillium chrysogenum var. chrysogenum extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 3 ... Mold Mix 3 ... Mold Mix 3 …

Cetalkonium

Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in different types of formulations. It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi. Cetalkonium is approved by the FDA for its use...
Approved

Benzylpenicillin

Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may also be used in some cases as prophylaxis against susceptible organisms. Natural penicillins are considered...
Approved
Vet approved
Matched Mixtures name: … SENTINA 6:3:3 ENJEKTABL TOZ İÇEREN FLAKON IM, 1ADET ... SENTINA 6:3:3 ENJEKTABL TOZ İÇEREN FLAKON IM, 1ADET …

Butaperazine

Butaperazine was approved in 1967 , and possibly discontinued in the 1980s .
Approved
Matched Iupac: … 1-{10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazin-2-yl}butan-1-one …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Displaying drugs 276 - 300 of 8872 in total