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Displaying drugs 2976 - 3000 of 3129 in total
Bindarit
Bindarit has been used in trials studying the prevention and treatment of Coronary Restenosis and Diabetic Nephropathy.
Investigational
Matched Categories: … Anti-Inflammatory Agents …
Tranilast
Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. In 1982, it was approved in Japan and South Korea for the management of bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis...
Investigational
Matched Categories: … Anti-Allergic Agents ... Anti-Inflammatory Agents …
Stepronin
Strepronin is a mucolytic drug. A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties. The viscosity of mucous secretions in the lungs is dependent upon the concentrations of mucoprotein as well as the presence of disulfide bonds between these macromolecules and DNA.
Experimental
Matched Categories: … Anti-Infective Agents …
Halofuginone
Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S....
Investigational
Vet approved
Matched Categories: … Anti-Infective Agents …
Ciglitazone
Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class.
Ciglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones. Several analogues were later developed, some of which—such as pioglitazone and troglitazone—made it to the market....
Experimental
Matched Description: … It is also an anti-hyperglycemic agent in the ob/ob murine model in vivo. …
Fentiazac
Experimental
Matched Categories: … Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal …
Sparfosic acid
Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen atom. This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein.
Experimental
Matched Categories: … Anti-Infective Agents …
Doxofylline
Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does...
Experimental
Matched Description: … The anti-asthmatic effects of doxophylline are mediated by other mechanisms, primarily through inhibiting …
Matched Categories: … Anti-Asthmatic Agents …
Matched Categories: … Anti-Asthmatic Agents …
CYT006-AngQb
CYT006-AngQb is a therapeutic vaccine in development for treatment of hypertension. It is designed to instruct the patient’s immune system to produce an antibody response against angiotensin II, a small peptide that causes blood vessels to narrow and results in increased blood pressure. It is a unique treatment modality that...
Investigational
Patupilone
Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol.
Experimental
Investigational
Matched Categories: … Anti-Bacterial Agents …
Amonafide
Amonafide is a substance that is being studied in the treatment of cancer. It belongs to the families of drugs called topoisomerase inhibitors and intercalating agents.
Investigational
Matched Categories: … Anti-Infective Agents …
Azidocillin
Azidocillin is a penicillin antibiotic similir to ampicillin.
Experimental
Matched Categories: … Anti-Bacterial Agents …
Colforsin
Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.
Experimental
Investigational
Matched Categories: … Anti-Asthmatic Agents …
Cefroxadine
Cefroxadine is an orally available cephalosporin antibiotic. As part of its drug class, it shares structural properties to cefalexin as well as its activity spectrum. It was used in Italy but has since been withdrawn.
Withdrawn
Matched Categories: … Anti-Bacterial Agents …
Oltipraz
Oltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease.
Investigational
Matched Categories: … Anti-Infective Agents …
Acteoside
Acteoside is under investigation in clinical trial NCT02662283 (Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy).
Investigational
Matched Categories: … Anti-Infective Agents …
Displaying drugs 2976 - 3000 of 3129 in total