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Displaying drugs 3076 - 3100 of 3158 in total
Wortmannin
Wortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
Experimental
Matched Categories: … Anti-Infective Agents …
Dithiazanine
Dithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms and whipworms. However, its use is severely limited due to its toxicity. Dithiazanine iodide was associated with eight fatal cases of severe acidosis and shock between 1961 and 1964. Dithiazanine iodide has been withdrawn from...
Vet approved
Withdrawn
Matched Categories: … Anti-Infective Agents …
Sagopilone
Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to combat several forms of cancer. Epothilones are 16-member ring macrolides...
Investigational
Matched Categories: … Anti-Bacterial Agents …
Irsogladine
Irsogladine is under investigation in clinical trial NCT02581696 (The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers).
Investigational
Matched Categories: … Anti-Ulcer Agents …
TMC-310911
TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 infections. TMC-310911 has shown marked activity against a variety of HIV-1 strains, including multi-PI-resistant strains, and may be less likely to...
Investigational
Matched Categories: … Anti-HIV Agents …
Roxatidine acetate
Roxatidine acetate is a specific and competitive H2 receptor antagonist. It is currently approved in South Africa under the tradename Roxit.
Experimental
Matched Categories: … Anti-Ulcer Agents …
Tandospirone
Tandospirone has been used in trials studying the treatment of Schizophrenia.
Investigational
Matched Categories: … Anti-Anxiety Agents …
Technetium Tc-99m ciprofloxacin
99mTc-Ciprofloxacin is a new formulation of ciprofloxacin (INFECTON), being investigated as a radioimaging agent for the potential diagnosis of infection, including fever of unknown origin, osteomyelitis, wound infection, abdominal abscess, pneumonia, appendicitis and tuberculosis. INFECTON combines the widely used antibiotic, ciprofloxacin, with Technetium ((99m)Tc), the most commonly used radioisotope in...
Investigational
Matched Categories: … Anti-Bacterial Agents …
GS-441524
GS-441524 is an adenosine nucleotide analog antiviral, similar to remdesivir.[A203057,L13239] This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent.[A203057,A203057] GS-441524 continues to be studied in the treatment of Feline...
Experimental
Matched Categories: … Anti-Infective Agents …
Adrenomedullin
Adrenomedullin is under investigation in clinical trial NCT06072118 (Adrenomedullin for CADASIL).
Investigational
Matched Categories: … Anti-Asthmatic Agents …
Homidium
Homidium is a group II compound with trypanocidal effects.
Investigational
Matched Categories: … Anti-Infective Agents …
Bergapten
Bergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis).
Investigational
Matched Categories: … Anti-Inflammatory Agents …
Seratrodast
Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
Experimental
Matched Categories: … Anti-Asthmatic Agents ... Anti-Inflammatory Agents …
Molnupiravir
Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of N4-hydroxycytidine.[A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed in vivo, and distributes into tissues where it becomes the active 5’-triphosphate form. The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as...
Investigational
Matched Categories: … Anti-Infective Agents …
Fludiazepam
Fludiazepam is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a scheduled drug in the U.S., but is approved for use in Japan.
Experimental
Illicit
Matched Categories: … Anti-Anxiety Agents …
Lisofylline
Lisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
Investigational
Matched Categories: … Anti-Inflammatory Agents …
Displaying drugs 3076 - 3100 of 3158 in total