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Displaying drugs 3126 - 3150 of 9620 in total
Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Investigational
Matched Synonyms: … 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1h-1,3-benzimidazole ... 1h-benzimidazole, 5,6-dibromo-1-(1-methylethyl)-4-nitro-2-(4-piperidinyl)- ... 5,6-dibromo-1-(1-methylethyl)-4-nitro-2-(4-piperidinyl)-1h-benzimidazole …
Matched Iupac: … 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1H-1,3-benzodiazole …
Perillyl alcohol is under investigation in clinical trial NCT02704858 (Safety and Efficacy Study in Recurrent Grade IV Glioma).
Investigational
Matched Synonyms: … P-MENTHA-1,8-DIEN-7-OL ... (±)-1-CYCLOHEXENE-1-METHANOL, 4-(1-METHYLETHENYL)- ... 1-CYCLOHEXENE-1-METHANOL, 4-(1-METHYLETHENYL)- …
Matched Iupac: … [(4S)-4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]methanol …
Investigational
Matched Synonyms: … 5,5,11-trioxo-n-((2-(trifluoromethyl)-1,3-thiazol-5-yl)methyl)-10,11-dihydro-5h- 5.lambda.6-dibenzo(b …
Investigational
Matched Synonyms: … Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2.beta.,3.beta.,5.beta.,22r)- …
Matched Iupac: … (1S,3aS,5aR,7R,8S,9aR,9bR,11aR)-3a,7,8-trihydroxy-9a,11a-dimethyl-1-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan …
Cadisegliatin is under investigation in clinical trial NCT06334133 (Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes).
Investigational
Matched Synonyms: … 2-((2-(3-cyclohexyl-3-((1r,4r)-4-propoxycyclohexyl)ureido)thiazol-5-yl)thio)acetic acid ... [(2-{[cyclohexyl(trans-4-propoxycyclohexyl)carbamoyl]amino}-1,3-thiazol-5-yl)sulfanyl]acetic acid …
Matched Description: … Cadisegliatin is under investigation in clinical trial NCT06334133 (Cadisegliatin as Adjunctive Therapy in Type 1
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Investigational
Matched Synonyms: … 3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine ... 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Investigational
Matched Synonyms: … Cyclopropanecarboxamide, N-[5-[[5-[[(3R)-hexahydro-3-methyl-4-(1-oxo-2-propen-1-yl)-1H-1,4-diazepin-1 ... ]-1,3-thiazol-2-yl}cyclopropanecarboxamide ... N-{5-[(5-{[(3R)-4-(prop-2-enoyl)-3-methyl-1,4-diazepan-1-yl]carbonyl}-4-methoxy-2-methylphenyl)sulfanyl …
Tozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).
Investigational
Matched Synonyms: … N6.27-(6-(2-(7-(1,1-DIMETHYL-3-(4-SULFONATOBUTYL)-1H-BENZO(E)INDOL-1-IUM-2-YL)HEPTA-2,4,6-TRIENYLIDENE ... )-1,1-DIMETHYL-1,2-DIHYDRO-3H-BENZO(E)INDOL-3-YL)HEXANOYL)(15-ARGININE(K>R),23-ARGININE(K>R))CHLOROTOXIN …
Investigational
Matched Synonyms: … Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal …
H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine . It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no such preferential targeting . H3B-8800 was granted orphan drug status by the FDA in August 2017 and...
Investigational
Matched Synonyms: … )-1-METHYL-5-(2-PYRIDINYL)-1,3-HEXADIEN-1-YL)-12-OXOOXACYCLODODEC-4-EN-6-YL ESTER ... 3,7-dimethyl-12-oxo-2-[(2E,4E,6R)-6-(2-pyridinyl)-2,4-heptadien-2-yl]oxacyclododec-4-en-6-yl 4-methyl-1- ... 12-Oxo-2-[(2E,4E,6R)-6-(Pyridin-2-Yl)Hepta-2,4-Dien-2-Yl]Oxacyclododec-4-En-6-Yl 4-Methylpiperazine-1- …
Matched Iupac: … oxacyclododec-4-en-6-yl 4-methylpiperazine-1-carboxylate ... 3S,4E,6S,7R,10R)-7,10-dihydroxy-3,7-dimethyl-12-oxo-2-[(4E,6R)-6-(pyridin-2-yl)hepta-2,4-dien-2-yl]-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Synonyms: … L-glutamic acid, n-(4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo(1,5-f)pteridin-8(9h)-yl)benzoyl)- …
Matched Iupac: … (2S)-2-[(4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic …
Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria. Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans.
Experimental
Vet approved
Matched Synonyms: … -1,5:8,4-dipyranos-1-yl)-2-deoxy-D-streptamine ... 4-O-((8R)-2-amino-8-O-(4-amino-4-deoxy-α-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo …
Matched Iupac: … ]oxy}-4-hydroxy-3-(methylamino)-octahydropyrano[3,2-b]pyran-2-yl]oxy}-5-amino-6-(hydroxymethyl)oxane- ... (2R,3R,4S,5S,6S)-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl …
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 ... ALL-P-AMBO-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5 ... ')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-O-METHYL-P-THIOGUANYLYL …
Matched Description: … Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients …
Matched Salts cas: … 1613607-40-1
Investigational
Matched Synonyms: … expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, Flt3 ligand, IL-7, …
Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
Investigational
Matched Synonyms: … (5R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin ... (5R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one ... 2-oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl) …
Matched Iupac: … (5R)-3-[3-fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Synonyms: … methyl (R)-4-((3S,5R,7R,8R,9S,10S,13R,14S,17R)-7-hydroxy-10,13-dimethyl-3-((4-((pyridin-3- ylmethyl)amino ... .-(1-methylethyl)-, cyano(3-phenoxyphenyl)methyl ester ... Cyano(3-phenoxyphenyl)methyl 4-chloro-.alpha.-(1-methylethyl)benzeneacetate …
Matched Iupac: … cyano(3-phenoxyphenyl)methyl 2-(4-chlorophenyl)-3-methylbutanoate …
Investigational
Matched Synonyms: … -, cyclic (2->7)-disulfide ... H-(4-amino-3-iodo)-d-phe-c(cys-(3-iodo)-tyr-d-trp-lys-val-cys)-thr-nh2 ... H-(4-amino-3-iodo)-D-Phe-c[Cys-(3-iodo)-Tyr-D-Trp-Lys-Val-Cys]-Thr-NH2 …
Matched Iupac: … )-16-[(4-hydroxy-3-iodophenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-7-(propan-2-yl ... (2S,3R)-2-{[(4R,7S,10S,13R,16S,19R)-19-[(2R)-2-amino-3-(4-amino-3-iodophenyl)propanamido]-10-(4-aminobutyl ... )-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]formamido}-3-hydroxybutanamide …
Investigational
Matched Synonyms: … Benzamide, N-(6-(2,6-dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo(3,4-B)pyridin-3-yl)-4-(3,3-dimethyl-1- …
Zelpultide alfa is a recombinant human surfactant protein D.
Investigational
Matched Synonyms: … HUMAN PULMONARY SURFACTANT-ASSOCIATED PROTEIN D (PSPD, SURFACTANT PROTEIN D, SP-D, COLLECTIN-7, SURFACTANT …
Investigational
Matched Synonyms: … -CHAIN, DIMER, THIOETHER WITH N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOH ... IMMUNOGLOBULIN G1, ANTI-(HUMAN B7 HOMOLOG 3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .GAMMA ... .1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .KAPPA. …
Experimental
Investigational
Matched Mixtures name: … SIMFLAT 40MG/80 MG FİLM KAPLI TABLET, 90 ADET ... DOLOSPAS 40 MG/80 MG FİLM KAPLI TABLET, 90 ADET …
Matched Products: … EKSPAZ 40 MG FILM TABLET, 90 ADET ... SPADIS 40 MG TABLET, 90 ADET ... PENSOTIL 40 MG FILM TABLET,90 ADET …
Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.
Investigational
Matched Description: … Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. …
Matched Salts cas: … 150821-03-7
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … PRANLUX 100 MG SAŞE, 90 SAŞE ... PRANLUX 50 MG SAŞE, 90 SAŞE ... PRANLUX 70 MG SAŞE, 90 SAŞE …
Investigational
PEN-866 is under investigation in clinical trial NCT03221400 (PEN-866 in Patients With Advanced Solid Malignancies).
Investigational
Matched Iupac: … 21),2,4,6,8,10,15(20)-heptaen-7-yl 4-[2-(5-{3-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-5-oxo-4,5-dihydro ... -1H-1,2,4-triazol-4-yl}-1H-indol-1-yl)ethyl]piperidine-1-carboxylate ... diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1( …
Displaying drugs 3126 - 3150 of 9620 in total