Displaying drugs 301 - 325 of 10304 in total
Simeprevir
Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Iupac: … (1R,4R,6R,7Z,15R,17R)-N-(cyclopropanesulfonyl)-17-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol ... -2-yl]quinolin-4-yl}oxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.0^{4,6}]octadec-7-ene-4-carboxamide …
Matched Description: … Simeprevir is also used in treatment of HCV genotype 4 patients with or without cirrhosis and is taken ... sofosbuvir treatment for genotype 1 or PEG-Interferon/ribavirin combination therapy for genotype 1 or 4. …
Matched Description: … Simeprevir is also used in treatment of HCV genotype 4 patients with or without cirrhosis and is taken ... sofosbuvir treatment for genotype 1 or PEG-Interferon/ribavirin combination therapy for genotype 1 or 4. …
Influenza A virus A/Victoria/210/2009 X-187 (H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Influenza A virus A/Victoria/210/2009 X-187 (H3N2) antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Influenza A virus A/Victoria/2570/2019 IVR-215 (H1N1) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Influenza A virus A/Victoria/2570/2019 IVR-215 (H1N1) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Dexibuprofen
Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a...
Approved
Investigational
Matched Synonyms: … (2S)-2-(4-isobutylphenyl)propanoic acid ... (S)-α-methyl-4-(2-methylpropyl)benzeneacetic acid …
Matched Iupac: … (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Iupac: … (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Dacomitinib
Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. Dacomitinib was developed by Pfizer Inc and approved by the FDA on...
Approved
Investigational
Matched Iupac: … (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide …
Matched Description: … Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sertindole
Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one …
Matched Iupac: … 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Serdolect 4 mg - Filmtabletten ... SERDOLECT 4 MG FILM KAPLI TABLET, 30 ADET …
Matched Iupac: … 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Serdolect 4 mg - Filmtabletten ... SERDOLECT 4 MG FILM KAPLI TABLET, 30 ADET …
Influenza A virus A/Brisbane/59/2007 (H1N1) hemagglutinin antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Investigational
Naldemedine
Naldemedine is an opioid receptor antagonist [FDA Label]. It is a modified form of DB00704 to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier. Naldemedine was approved in 2017 in both the US and...
Approved
Investigational
Matched Iupac: … (1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,14,17-trihydroxy-N-[2-(3-phenyl-1,2,4-oxadiazol-5-yl)propan- ... 2-yl]-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7,9,11(18),14-tetraene-15-carboxamide …
Matched Salts cas: … 1345728-04-2 …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Salts cas: … 1345728-04-2 …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Nitroprusside
Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Products: … NITROPRUSIATO DE SODIO 50 MG/2 ML INYECTABLE ... NITROPRUSIATO DE SODIO SOLUCION INYECTABLE POR 2 ML ... Nitroprussid-Natrium AraMed 50 mg/2 ml Infusionslösung …
Polyquaternium-10 (400 cps at 2%)
Polyquaternium-10 is a quaternized hydroxyethyl cellulose and a polycationic polymer. It is commonly found in cosmetics and personal care products to mainly reduce static electricity and form films.
Approved
Matched Name: … Polyquaternium-10 (400 cps at 2%) …
Methyldopa
Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading...
Approved
Matched Iupac: … (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid …
Matched Description: … Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading to the inhibition …
Matched Salts cas: … 2508-79-4 …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Description: … Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading to the inhibition …
Matched Salts cas: … 2508-79-4 …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Vilazodone
Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Iupac: … 5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide …
Matched Salts cas: … 163521-08-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 163521-08-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lurasidone
Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Iupac: … (1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}-4-azatricyclo …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Antagonists …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Antagonists …
Ziprasidone
Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Iupac: … 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-2,3-dihydro-1H-indol-2-one …
Buspirone
Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspirone does...
Approved
Investigational
Matched Synonyms: … 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione …
Matched Iupac: … 8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione …
Matched Salts cas: … 33386-08-2 …
Matched Iupac: … 8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione …
Matched Salts cas: … 33386-08-2 …
Thiethylperazine
A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
Approved
Withdrawn
Matched Synonyms: … 2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Iupac: … 2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Iupac: … 2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Drostanolone propionate
Approved
Illicit
Emtricitabine
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Synonyms: … (−)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one ... (2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone ... 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one …
Matched Iupac: … 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Description: … [L9019] Emtricitabine was granted FDA approval on 2 July 2003.[L9019] …
Matched Iupac: … 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Description: … [L9019] Emtricitabine was granted FDA approval on 2 July 2003.[L9019] …
Glimepiride
First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Iupac: … 3-ethyl-4-methyl-2-oxo-N-(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)- …
Matched Description: … Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by ... Sulfonylureas are one of the insulin secretagogues widely used for the management of type 2 diabetes ... glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 …
Matched Mixtures name: … AMARYL®M 4 MG/ 1000 MG ... DUERID 30/4 MG TABLET, 30 ADET ... DUERID 30/4 MG TABLET, 90 ADET …
Matched Products: … GLUVAS 4 ... ANPIRIDE 4 ... DIAVERSA 4 …
Matched Description: … Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by ... Sulfonylureas are one of the insulin secretagogues widely used for the management of type 2 diabetes ... glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 …
Matched Mixtures name: … AMARYL®M 4 MG/ 1000 MG ... DUERID 30/4 MG TABLET, 30 ADET ... DUERID 30/4 MG TABLET, 90 ADET …
Matched Products: … GLUVAS 4 ... ANPIRIDE 4 ... DIAVERSA 4 …
Olanzapine
Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Synonyms: … 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine …
Matched Iupac: … 5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),5,8,10,12 …
Matched Iupac: … 5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),5,8,10,12 …
Vardenafil
Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Iupac: … 2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propyl-1H,4H-imidazo[4,3-f][1,2,4]triazin ... -4-one …
Matched Products: … VAREKSİL 20 MG FİLM KAPLI TABLET, 2 ADET ... LEVITRA 20 MG FILM KAPLI TABLET, 2 ADET ... LOVİTREC 20 MG FİLM KAPLI TABLET, 2 ADET …
Matched Products: … VAREKSİL 20 MG FİLM KAPLI TABLET, 2 ADET ... LEVITRA 20 MG FILM KAPLI TABLET, 2 ADET ... LOVİTREC 20 MG FİLM KAPLI TABLET, 2 ADET …
Flucloxacillin
Antibiotic analog of cloxacillin.
Approved
Investigational
Matched Synonyms: … -4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... 3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin ... (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Salts cas: … 34214-51-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Flucloxacillin WABO 2 g Pulver zur Herstellung einer Injektions-/Infusionslösung ... Flucloxacillin WABO 4 g Pulver zur Herstellung einer Injektions-/Infusionslösung …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Salts cas: … 34214-51-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Flucloxacillin WABO 2 g Pulver zur Herstellung einer Injektions-/Infusionslösung ... Flucloxacillin WABO 4 g Pulver zur Herstellung einer Injektions-/Infusionslösung …
Domperidone
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Synonyms: … 5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone ... 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2 ... 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2 …
Matched Iupac: … 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3 ... -benzodiazol-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3 ... -benzodiazol-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 301 - 325 of 10304 in total